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Lauren E Henke, John D Pfeifer, Thomas J Baranski, Todd DeWees and Perry W Grigsby

2014 – have demonstrated a clear difference in genetic profiles and clinical outcomes between the two, linking C-PTC to increased prevalence of thyroid capsule invasion, LNM, disease recurrence and mortality ( 11 , 12 , 13 ). However, pathologic

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Dario de Biase, Federica Torricelli, Moira Ragazzi, Benedetta Donati, Elisabetta Kuhn, Michela Visani, Giorgia Acquaviva, Annalisa Pession, Giovanni Tallini, Simonetta Piana and Alessia Ciarrocchi

subgroup ( Table 1 ). Lung was the most frequent metastatic site (54.1%, data not shown). Of 151 cases, 88 were diagnosed as ‘classic-PTC’ (C-PTC, 58.3%), 25 as ‘Tall-cell Variant-PTC’ (TCV-PTC, 16.6%), 17 as ‘Follicular Variant-PTC’ (FV-PTC, 11.3%), 3 as