Lilit Egshatyan
Lilit Egshatyan
‘Research of Age and Age-Associated Conditions’ Department, Laboratory of Bioinformatics, The ‘Russian Clinical Research Center for Gerontology’, ‘Chronic Noncommunicable Diseases Primary Prevention in the Healthcare System’ Department, Moscow Institute of Physics and Technology, National Research Centre for Preventive Medicine, National Research Centre for Preventive Medicine, Building 10, Petroverigskiy Lane, Moscow RF 101000, Russian Federation
Search for other papers by Lilit Egshatyan in
Google Scholar
PubMed
Search for other papers by Lilit Egshatyan in
Google Scholar
PubMed
Daria Kashtanova
Daria Kashtanova
‘Research of Age and Age-Associated Conditions’ Department, Laboratory of Bioinformatics, The ‘Russian Clinical Research Center for Gerontology’, ‘Chronic Noncommunicable Diseases Primary Prevention in the Healthcare System’ Department, Moscow Institute of Physics and Technology, National Research Centre for Preventive Medicine, National Research Centre for Preventive Medicine, Building 10, Petroverigskiy Lane, Moscow RF 101000, Russian Federation
Search for other papers by Daria Kashtanova in
Google Scholar
PubMed
Search for other papers by Daria Kashtanova in
Google Scholar
PubMed
Anna Popenko
Anna Popenko
‘Research of Age and Age-Associated Conditions’ Department, Laboratory of Bioinformatics, The ‘Russian Clinical Research Center for Gerontology’, ‘Chronic Noncommunicable Diseases Primary Prevention in the Healthcare System’ Department, Moscow Institute of Physics and Technology, National Research Centre for Preventive Medicine, National Research Centre for Preventive Medicine, Building 10, Petroverigskiy Lane, Moscow RF 101000, Russian Federation
Search for other papers by Anna Popenko in
Google Scholar
PubMed
Search for other papers by Anna Popenko in
Google Scholar
PubMed
Olga Tkacheva
Olga Tkacheva
‘Research of Age and Age-Associated Conditions’ Department, Laboratory of Bioinformatics, The ‘Russian Clinical Research Center for Gerontology’, ‘Chronic Noncommunicable Diseases Primary Prevention in the Healthcare System’ Department, Moscow Institute of Physics and Technology, National Research Centre for Preventive Medicine, National Research Centre for Preventive Medicine, Building 10, Petroverigskiy Lane, Moscow RF 101000, Russian Federation
Search for other papers by Olga Tkacheva in
Google Scholar
PubMed
Search for other papers by Olga Tkacheva in
Google Scholar
PubMed
Alexander Tyakht
Alexander Tyakht
‘Research of Age and Age-Associated Conditions’ Department, Laboratory of Bioinformatics, The ‘Russian Clinical Research Center for Gerontology’, ‘Chronic Noncommunicable Diseases Primary Prevention in the Healthcare System’ Department, Moscow Institute of Physics and Technology, National Research Centre for Preventive Medicine, National Research Centre for Preventive Medicine, Building 10, Petroverigskiy Lane, Moscow RF 101000, Russian Federation
Search for other papers by Alexander Tyakht in
Google Scholar
PubMed
Search for other papers by Alexander Tyakht in
Google Scholar
PubMed
Dmitry Alexeev
Dmitry Alexeev
‘Research of Age and Age-Associated Conditions’ Department, Laboratory of Bioinformatics, The ‘Russian Clinical Research Center for Gerontology’, ‘Chronic Noncommunicable Diseases Primary Prevention in the Healthcare System’ Department, Moscow Institute of Physics and Technology, National Research Centre for Preventive Medicine, National Research Centre for Preventive Medicine, Building 10, Petroverigskiy Lane, Moscow RF 101000, Russian Federation
Search for other papers by Dmitry Alexeev in
Google Scholar
PubMed
Search for other papers by Dmitry Alexeev in
Google Scholar
PubMed
Natalia Karamnova
Natalia Karamnova
‘Research of Age and Age-Associated Conditions’ Department, Laboratory of Bioinformatics, The ‘Russian Clinical Research Center for Gerontology’, ‘Chronic Noncommunicable Diseases Primary Prevention in the Healthcare System’ Department, Moscow Institute of Physics and Technology, National Research Centre for Preventive Medicine, National Research Centre for Preventive Medicine, Building 10, Petroverigskiy Lane, Moscow RF 101000, Russian Federation
Search for other papers by Natalia Karamnova in
Google Scholar
PubMed
Search for other papers by Natalia Karamnova in
Google Scholar
PubMed
Elena Kostryukova
Elena Kostryukova
‘Research of Age and Age-Associated Conditions’ Department, Laboratory of Bioinformatics, The ‘Russian Clinical Research Center for Gerontology’, ‘Chronic Noncommunicable Diseases Primary Prevention in the Healthcare System’ Department, Moscow Institute of Physics and Technology, National Research Centre for Preventive Medicine, National Research Centre for Preventive Medicine, Building 10, Petroverigskiy Lane, Moscow RF 101000, Russian Federation
‘Research of Age and Age-Associated Conditions’ Department, Laboratory of Bioinformatics, The ‘Russian Clinical Research Center for Gerontology’, ‘Chronic Noncommunicable Diseases Primary Prevention in the Healthcare System’ Department, Moscow Institute of Physics and Technology, National Research Centre for Preventive Medicine, National Research Centre for Preventive Medicine, Building 10, Petroverigskiy Lane, Moscow RF 101000, Russian Federation
‘Research of Age and Age-Associated Conditions’ Department, Laboratory of Bioinformatics, The ‘Russian Clinical Research Center for Gerontology’, ‘Chronic Noncommunicable Diseases Primary Prevention in the Healthcare System’ Department, Moscow Institute of Physics and Technology, National Research Centre for Preventive Medicine, National Research Centre for Preventive Medicine, Building 10, Petroverigskiy Lane, Moscow RF 101000, Russian Federation
Search for other papers by Elena Kostryukova in
Google Scholar
PubMed
‘Research of Age and Age-Associated Conditions’ Department, Laboratory of Bioinformatics, The ‘Russian Clinical Research Center for Gerontology’, ‘Chronic Noncommunicable Diseases Primary Prevention in the Healthcare System’ Department, Moscow Institute of Physics and Technology, National Research Centre for Preventive Medicine, National Research Centre for Preventive Medicine, Building 10, Petroverigskiy Lane, Moscow RF 101000, Russian Federation
‘Research of Age and Age-Associated Conditions’ Department, Laboratory of Bioinformatics, The ‘Russian Clinical Research Center for Gerontology’, ‘Chronic Noncommunicable Diseases Primary Prevention in the Healthcare System’ Department, Moscow Institute of Physics and Technology, National Research Centre for Preventive Medicine, National Research Centre for Preventive Medicine, Building 10, Petroverigskiy Lane, Moscow RF 101000, Russian Federation
Search for other papers by Elena Kostryukova in
Google Scholar
PubMed
Vladislav Babenko
Vladislav Babenko
‘Research of Age and Age-Associated Conditions’ Department, Laboratory of Bioinformatics, The ‘Russian Clinical Research Center for Gerontology’, ‘Chronic Noncommunicable Diseases Primary Prevention in the Healthcare System’ Department, Moscow Institute of Physics and Technology, National Research Centre for Preventive Medicine, National Research Centre for Preventive Medicine, Building 10, Petroverigskiy Lane, Moscow RF 101000, Russian Federation
Search for other papers by Vladislav Babenko in
Google Scholar
PubMed
Search for other papers by Vladislav Babenko in
Google Scholar
PubMed
Maria Vakhitova
Maria Vakhitova
‘Research of Age and Age-Associated Conditions’ Department, Laboratory of Bioinformatics, The ‘Russian Clinical Research Center for Gerontology’, ‘Chronic Noncommunicable Diseases Primary Prevention in the Healthcare System’ Department, Moscow Institute of Physics and Technology, National Research Centre for Preventive Medicine, National Research Centre for Preventive Medicine, Building 10, Petroverigskiy Lane, Moscow RF 101000, Russian Federation
Search for other papers by Maria Vakhitova in
Google Scholar
PubMed
Search for other papers by Maria Vakhitova in
Google Scholar
PubMed
Sergey Boytsov
Sergey Boytsov
‘Research of Age and Age-Associated Conditions’ Department, Laboratory of Bioinformatics, The ‘Russian Clinical Research Center for Gerontology’, ‘Chronic Noncommunicable Diseases Primary Prevention in the Healthcare System’ Department, Moscow Institute of Physics and Technology, National Research Centre for Preventive Medicine, National Research Centre for Preventive Medicine, Building 10, Petroverigskiy Lane, Moscow RF 101000, Russian Federation
Search for other papers by Sergey Boytsov in
Google Scholar
PubMed
Search for other papers by Sergey Boytsov in
Google Scholar
PubMed
then thawed; the DNA was extracted from each sample; sequencing of the variable V3–V4 16S rRNA gene regions was performed (after the total DNA isolation and library preparation) by using an MiSeq Reagent Kit v2 (300 cycles) and MiSDefault (Illumina, San
Niels B Dalsgaard
Niels B Dalsgaard
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Search for other papers by Niels B Dalsgaard in
Google Scholar
PubMed
Search for other papers by Niels B Dalsgaard in
Google Scholar
PubMed
Lærke S Gasbjerg
Lærke S Gasbjerg
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Search for other papers by Lærke S Gasbjerg in
Google Scholar
PubMed
Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Search for other papers by Lærke S Gasbjerg in
Google Scholar
PubMed
Laura S Hansen
Laura S Hansen
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Search for other papers by Laura S Hansen in
Google Scholar
PubMed
Search for other papers by Laura S Hansen in
Google Scholar
PubMed
Dennis S Nielsen
Dennis S Nielsen
Department of Food Science, Faculty of Science, University of Copenhagen, Copenhagen, Denmark
Search for other papers by Dennis S Nielsen in
Google Scholar
PubMed
Search for other papers by Dennis S Nielsen in
Google Scholar
PubMed
Torben S Rasmussen
Torben S Rasmussen
Department of Food Science, Faculty of Science, University of Copenhagen, Copenhagen, Denmark
Search for other papers by Torben S Rasmussen in
Google Scholar
PubMed
Search for other papers by Torben S Rasmussen in
Google Scholar
PubMed
Filip K Knop
Filip K Knop
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Steno Diabetes Center Copenhagen, Gentofte, Denmark
Search for other papers by Filip K Knop in
Google Scholar
PubMed
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Steno Diabetes Center Copenhagen, Gentofte, Denmark
Search for other papers by Filip K Knop in
Google Scholar
PubMed
course with the alpha-glucosidase inhibitor, acarbose, on GM profiles (evaluated by 16S rRNA gene-based high-throughput sequencing) in Caucasian individuals with metformin-treated T2D. Materials and methods Ethics and study approvals This
Emmi Naskali
Emmi Naskali
Department of Dermatology, Allergology and Venereology, University of Helsinki, and Helsinki University Central Hospital, Helsinki, Finland
Search for other papers by Emmi Naskali in
Google Scholar
PubMed
Search for other papers by Emmi Naskali in
Google Scholar
PubMed
Katja Dettmer
Katja Dettmer
Institute of Functional Genomics, University of Regensburg, Regensburg, Germany
Search for other papers by Katja Dettmer in
Google Scholar
PubMed
Search for other papers by Katja Dettmer in
Google Scholar
PubMed
Peter J Oefner
Peter J Oefner
Institute of Functional Genomics, University of Regensburg, Regensburg, Germany
Search for other papers by Peter J Oefner in
Google Scholar
PubMed
Search for other papers by Peter J Oefner in
Google Scholar
PubMed
Pedro A B Pereira
Pedro A B Pereira
Institute of Biotechnology, DNA Sequencing and Genomics Laboratory, University of Helsinki, Helsinki, Finland
Search for other papers by Pedro A B Pereira in
Google Scholar
PubMed
Search for other papers by Pedro A B Pereira in
Google Scholar
PubMed
Kai Krohn
Kai Krohn
Clinical Research Institute HUCH Ltd, Biomedicum Helsinki 1, Helsinki, Finland
Search for other papers by Kai Krohn in
Google Scholar
PubMed
Search for other papers by Kai Krohn in
Google Scholar
PubMed
Petri Auvinen
Petri Auvinen
Institute of Biotechnology, DNA Sequencing and Genomics Laboratory, University of Helsinki, Helsinki, Finland
Search for other papers by Petri Auvinen in
Google Scholar
PubMed
Search for other papers by Petri Auvinen in
Google Scholar
PubMed
Annamari Ranki
Annamari Ranki
Department of Dermatology, Allergology and Venereology, University of Helsinki, and Helsinki University Central Hospital, Helsinki, Finland
Search for other papers by Annamari Ranki in
Google Scholar
PubMed
Search for other papers by Annamari Ranki in
Google Scholar
PubMed
Nicolas Kluger
Nicolas Kluger
Department of Dermatology, Allergology and Venereology, University of Helsinki, and Helsinki University Central Hospital, Helsinki, Finland
Search for other papers by Nicolas Kluger in
Google Scholar
PubMed
Search for other papers by Nicolas Kluger in
Google Scholar
PubMed
), anthranilic acid (AA), 3-hydroxyanthranilic acid (HAA), 5-hydroxyindole-3-acetic acid (HIAA), indole-3-lactic acid (ILA), indole-3-acetic acid (IAA) and indole-3-propionic acid (IPA). Gut microbiome Stool specimens for 16S rRNA-based gut microbiome
Yao Su
Yao Su
Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Search for other papers by Yao Su in
Google Scholar
PubMed
Search for other papers by Yao Su in
Google Scholar
PubMed
Li Chen
Li Chen
Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Search for other papers by Li Chen in
Google Scholar
PubMed
Search for other papers by Li Chen in
Google Scholar
PubMed
Dong-Yao Zhang
Dong-Yao Zhang
Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Search for other papers by Dong-Yao Zhang in
Google Scholar
PubMed
Search for other papers by Dong-Yao Zhang in
Google Scholar
PubMed
Xu-Pei Gan
Xu-Pei Gan
Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Search for other papers by Xu-Pei Gan in
Google Scholar
PubMed
Search for other papers by Xu-Pei Gan in
Google Scholar
PubMed
Yan-Nan Cao
Yan-Nan Cao
Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Search for other papers by Yan-Nan Cao in
Google Scholar
PubMed
Search for other papers by Yan-Nan Cao in
Google Scholar
PubMed
De-Cui Cheng
De-Cui Cheng
Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Search for other papers by De-Cui Cheng in
Google Scholar
PubMed
Search for other papers by De-Cui Cheng in
Google Scholar
PubMed
Wen-Yu Liu
Wen-Yu Liu
Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Search for other papers by Wen-Yu Liu in
Google Scholar
PubMed
Search for other papers by Wen-Yu Liu in
Google Scholar
PubMed
Fei-Fei Li
Fei-Fei Li
Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Search for other papers by Fei-Fei Li in
Google Scholar
PubMed
Search for other papers by Fei-Fei Li in
Google Scholar
PubMed
Xian-Ming Xu
Xian-Ming Xu
Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Search for other papers by Xian-Ming Xu in
Google Scholar
PubMed
Search for other papers by Xian-Ming Xu in
Google Scholar
PubMed
Hong-Kun Wang
Hong-Kun Wang
Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Search for other papers by Hong-Kun Wang in
Google Scholar
PubMed
Search for other papers by Hong-Kun Wang in
Google Scholar
PubMed
extraction kit, and the quality of the extracted DNA was detected using a Qubit dsDNA HS Assay Kit (Carlsbad, CA, USA). After eliminating the samples that did not meet the test standard, the V3–V4 variable region of the 16S rRNA was specifically amplified by
Ling Zhou
Ling Zhou
Department of Gynecology of Traditional Chinese Medicine, Changhai Hospital, Naval Medical University, Shanghai, China
Search for other papers by Ling Zhou in
Google Scholar
PubMed
Search for other papers by Ling Zhou in
Google Scholar
PubMed
Zhexin Ni
Zhexin Ni
Department of Gynecology of Traditional Chinese Medicine, Changhai Hospital, Naval Medical University, Shanghai, China
Search for other papers by Zhexin Ni in
Google Scholar
PubMed
Search for other papers by Zhexin Ni in
Google Scholar
PubMed
Wen Cheng
Wen Cheng
Department of Gynecology of Traditional Chinese Medicine, Changhai Hospital, Naval Medical University, Shanghai, China
Search for other papers by Wen Cheng in
Google Scholar
PubMed
Search for other papers by Wen Cheng in
Google Scholar
PubMed
Jin Yu
Jin Yu
Department of Gynecology of Traditional Chinese Medicine, Changhai Hospital, Naval Medical University, Shanghai, China
Search for other papers by Jin Yu in
Google Scholar
PubMed
Search for other papers by Jin Yu in
Google Scholar
PubMed
Shuai Sun
Shuai Sun
Department of Gynecology of Traditional Chinese Medicine, Changhai Hospital, Naval Medical University, Shanghai, China
Search for other papers by Shuai Sun in
Google Scholar
PubMed
Search for other papers by Shuai Sun in
Google Scholar
PubMed
Dongxia Zhai
Dongxia Zhai
Department of Gynecology of Traditional Chinese Medicine, Changhai Hospital, Naval Medical University, Shanghai, China
Search for other papers by Dongxia Zhai in
Google Scholar
PubMed
Search for other papers by Dongxia Zhai in
Google Scholar
PubMed
Chaoqin Yu
Chaoqin Yu
Department of Gynecology of Traditional Chinese Medicine, Changhai Hospital, Naval Medical University, Shanghai, China
Search for other papers by Chaoqin Yu in
Google Scholar
PubMed
Search for other papers by Chaoqin Yu in
Google Scholar
PubMed
Zailong Cai
Zailong Cai
Department of Biochemistry and Molecular Biology, Naval Medical University, Shanghai, China
Search for other papers by Zailong Cai in
Google Scholar
PubMed
Search for other papers by Zailong Cai in
Google Scholar
PubMed
Polycystic ovary syndrome (PCOS) is a chronic endocrine and metabolic disease. Gut microbiota is closely related to many chronic diseases. In this study, we conducted a cross-sectional study and recruited 30 obese (OG) and 30 non-obese (NG) women with PCOS, 30 healthy women (NC) and 11 healthy but obese women (OC) as controls to investigate the characteristic gut microbiota and its metabolic functions in obese and non-obese patients with PCOS. The blood and non-menstrual faecal samples of all the participants were collected and analysed. As a result, the Hirsutism score, LH/FSH and serum T level in NG and OG both increased significantly compared with their controls (P < 0.05). High-throughput 16S rRNA gene sequencing revealed that the abundance and diversity of the gut microbiota changed in patients with PCOS. The linear discriminant analysis (LDA) indicated that Lactococcus was the characteristic gut microbiota in NG, while Coprococcus_2 in OG. Correlation heatmap analysis revealed that the sex hormones and insulin levels in human serum were closely related to the changes in the gut microbiota of NG and OG. Functional prediction analysis demonstrated that the citrate cycle pathway enriched both in NG and OG, and other 12 gut bacterial metabolic pathways enriched in NG. This study highlighted significant differences in the gut microbiota and predictive functions of obese and non-obese women with PCOS, thereby providing insights into the role and function of the gut microbiota that may contribute to the occurrence and development of PCOS in obese and non-obese women.
Mengxue Yang
Mengxue Yang
Department of Endocrinology, The Fifth People’s Hospital of Shanghai, Fudan University, Shanghai, China
Department of Endocrinology, Zunyi Medical University, Zunyi, China
Search for other papers by Mengxue Yang in
Google Scholar
PubMed
Department of Endocrinology, Zunyi Medical University, Zunyi, China
Search for other papers by Mengxue Yang in
Google Scholar
PubMed
Bowen Sun
Bowen Sun
Department of Endocrinology, Zunyi Medical University, Zunyi, China
Search for other papers by Bowen Sun in
Google Scholar
PubMed
Search for other papers by Bowen Sun in
Google Scholar
PubMed
Jianhui Li
Jianhui Li
Department of Endocrinology, Ningbo No. 2 Hospital, Ningbo, China
Search for other papers by Jianhui Li in
Google Scholar
PubMed
Search for other papers by Jianhui Li in
Google Scholar
PubMed
Bo Yang
Bo Yang
Department of Endocrinology, Zunyi Medical University, Zunyi, China
Search for other papers by Bo Yang in
Google Scholar
PubMed
Search for other papers by Bo Yang in
Google Scholar
PubMed
Jie Xu
Jie Xu
School of Public Health, Zunyi Medical University, Zunyi, China
Search for other papers by Jie Xu in
Google Scholar
PubMed
Search for other papers by Jie Xu in
Google Scholar
PubMed
Xue Zhou
Xue Zhou
Department of Endocrinology, Zunyi Medical University, Zunyi, China
Search for other papers by Xue Zhou in
Google Scholar
PubMed
Search for other papers by Xue Zhou in
Google Scholar
PubMed
Jie Yu
Jie Yu
School of Public Health, Zunyi Medical University, Zunyi, China
Search for other papers by Jie Yu in
Google Scholar
PubMed
Search for other papers by Jie Yu in
Google Scholar
PubMed
Xuan Zhang
Xuan Zhang
Department of Endocrinology, Zunyi Medical University, Zunyi, China
Search for other papers by Xuan Zhang in
Google Scholar
PubMed
Search for other papers by Xuan Zhang in
Google Scholar
PubMed
Qun Zhang
Qun Zhang
Department of Endocrinology, Ningbo No. 2 Hospital, Ningbo, China
Search for other papers by Qun Zhang in
Google Scholar
PubMed
Search for other papers by Qun Zhang in
Google Scholar
PubMed
Shan Zhou
Shan Zhou
Department of Endocrinology, Ningbo No. 2 Hospital, Ningbo, China
Search for other papers by Shan Zhou in
Google Scholar
PubMed
Search for other papers by Shan Zhou in
Google Scholar
PubMed
Xiaohua Sun
Xiaohua Sun
Department of Endocrinology, Ningbo No. 2 Hospital, Ningbo, China
Search for other papers by Xiaohua Sun in
Google Scholar
PubMed
Search for other papers by Xiaohua Sun in
Google Scholar
PubMed
targets, and sample-specific barcode sequences were used for PCR amplification of the variable regions of the 16S rRNA gene (Q5 HiFi DNA polymerase; NEB, Ipswich, MA, USA). The amplification products were subjected to 2% agarose gel electrophoresis, and
Ying Pei
Ying Pei
Research Centre of Basic Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China
Search for other papers by Ying Pei in
Google Scholar
PubMed
Search for other papers by Ying Pei in
Google Scholar
PubMed
Rui Wang
Rui Wang
School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China
Search for other papers by Rui Wang in
Google Scholar
PubMed
Search for other papers by Rui Wang in
Google Scholar
PubMed
Wanyu Chen
Wanyu Chen
Research Centre of Basic Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China
Search for other papers by Wanyu Chen in
Google Scholar
PubMed
Search for other papers by Wanyu Chen in
Google Scholar
PubMed
Shulin Yi
Shulin Yi
Research Centre of Basic Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China
Search for other papers by Shulin Yi in
Google Scholar
PubMed
Search for other papers by Shulin Yi in
Google Scholar
PubMed
Chen Huang
Chen Huang
Research Centre of Basic Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China
Search for other papers by Chen Huang in
Google Scholar
PubMed
Search for other papers by Chen Huang in
Google Scholar
PubMed
Shaochan Liang
Shaochan Liang
School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China
Search for other papers by Shaochan Liang in
Google Scholar
PubMed
Search for other papers by Shaochan Liang in
Google Scholar
PubMed
Hongying Cao
Hongying Cao
School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China
Search for other papers by Hongying Cao in
Google Scholar
PubMed
Search for other papers by Hongying Cao in
Google Scholar
PubMed
Yifei Xu
Yifei Xu
Shenzhen Traditional Chinese Medicine Hospital, The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen, China
Search for other papers by Yifei Xu in
Google Scholar
PubMed
Search for other papers by Yifei Xu in
Google Scholar
PubMed
Bo Tan
Bo Tan
Research Centre of Basic Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China
Search for other papers by Bo Tan in
Google Scholar
PubMed
Search for other papers by Bo Tan in
Google Scholar
PubMed
.01 vs NFD group. # P < 0.05, ## P < 0.01 vs HGD group. Effects of HGD on the gut microbiota The composition of the gut microbiota was analyzed by bacterial 16S rRNA sequencing of the intestinal feces. After dereplication of unqualified
