Ayana Suzuki
Ayana Suzuki
Department of Diagnostic Pathology and Cytology, Kuma Hospital, Kobe, Japan
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Mitsuyoshi Hirokawa
Mitsuyoshi Hirokawa
Department of Diagnostic Pathology and Cytology, Kuma Hospital, Kobe, Japan
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Izumi Otsuka
Izumi Otsuka
Secretary Section, Kuma Hospital, Kobe, Japan
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Akihiro Miya
Akihiro Miya
Department of Surgery, Kuma Hospital, Kobe, Japan
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Akira Miyauchi
Akira Miyauchi
Department of Surgery, Kuma Hospital, Kobe, Japan
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Takashi Akamizu
Takashi Akamizu
Department of Internal Medicine, Kuma Hospital, Kobe, Japan
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length of the whole tumor and the solid area in three directions on ultrasound images using the formula ( Fig. 1 ). Whole tumor diameter (WTD; Fig. 1D ) and solid area diameter (SAD; Fig. 1A ) were defined as the maximum diameter in the three
Camila Aparecida Moma
Camila Aparecida Moma
Endocrinology Division, Department of Internal Medicine, Faculty of Medical Sciences, University of Campinas, Campinas, São Paulo, Brazil
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Icléia Siqueira Barreto
Icléia Siqueira Barreto
Department of Pathology, Faculty of Medical Sciences, University of Campinas, Campinas, São Paulo, Brazil
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Ligia Vera Montali Assumpção
Ligia Vera Montali Assumpção
Endocrinology Division, Department of Internal Medicine, Faculty of Medical Sciences, University of Campinas, Campinas, São Paulo, Brazil
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Denise Engelbrecht Zantut-Wittmann
Denise Engelbrecht Zantut-Wittmann
Endocrinology Division, Department of Internal Medicine, Faculty of Medical Sciences, University of Campinas, Campinas, São Paulo, Brazil
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methods and environmental risk factors such as obesity ( 3 , 4 , 5 , 6 ). Papillary thyroid carcinoma can occur multifocally, with about 30% corresponding to microcarcinomas (tumor diameter ≤ 1 cm), and most metastases arise in regional lymph nodes
Maria Luisa Garo
Maria Luisa Garo
Mathsly Research, Roma, Italy
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Désirée Deandreis
Désirée Deandreis
Division of Nuclear Medicine, Department of Medical Sciences, AOU Città della Salute e della Scienza, University of Turin, Turin, Italy
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Alfredo Campennì
Alfredo Campennì
Nuclear Medicine Unit, Department of Biomedical and Dental Sciences and Morpho-Functional Imaging, University of Messina, Messina, Italy
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Alexis Vrachimis
Alexis Vrachimis
Department of Nuclear Medicine, German Oncology Center, University Hospital of the European University, Limassol, Cyprus
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Petra Petranovic Ovcaricek
Petra Petranovic Ovcaricek
Department of Oncology and Nuclear Medicine, University Hospital Center Sestre Milosrdnice, Zagreb, Croatia
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Luca Giovanella
Luca Giovanella
Clinic for Nuclear Medicine and Molecular Imaging, Imaging Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland
Clinic for Nuclear Medicine, University Hospital of Zürich, Zürich, Switzerland
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Clinic for Nuclear Medicine, University Hospital of Zürich, Zürich, Switzerland
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) Age, sex, family history, histological variants (mixed vs follicular vs classic), T staging (T4 vs T3 vs T2 vs T1), N staging (N1b vs N1a vs N0/Nx), tumor number (multiple vs solitary), maximal tumor diameter, capsule invasion, perineuronal invasion
Ya Zhang
Ya Zhang
Endocrine and Diabetes Center, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
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Xiaoqiu Chu
Xiaoqiu Chu
Endocrine and Diabetes Center, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
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Yuling Liu
Yuling Liu
Department of Endocrinology, Zaozhuang Municipal Hospital, Zaozhuang, China
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Yueting Zhao
Yueting Zhao
Endocrine and Diabetes Center, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
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Xue Han
Xue Han
Endocrine and Diabetes Center, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
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Xin Hu
Xin Hu
Endocrine and Diabetes Center, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
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Pingping Xiang
Pingping Xiang
Endocrine and Diabetes Center, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
Key Laboratory of TCM Syndrome and Treatment of Yingbing (Thyroid Disease) of State Administration of Traditional Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
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Key Laboratory of TCM Syndrome and Treatment of Yingbing (Thyroid Disease) of State Administration of Traditional Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
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Guofang Chen
Guofang Chen
Endocrine and Diabetes Center, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
Key Laboratory of TCM Syndrome and Treatment of Yingbing (Thyroid Disease) of State Administration of Traditional Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
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Key Laboratory of TCM Syndrome and Treatment of Yingbing (Thyroid Disease) of State Administration of Traditional Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
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Chao Liu
Chao Liu
Endocrine and Diabetes Center, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
Key Laboratory of TCM Syndrome and Treatment of Yingbing (Thyroid Disease) of State Administration of Traditional Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
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Key Laboratory of TCM Syndrome and Treatment of Yingbing (Thyroid Disease) of State Administration of Traditional Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
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Shuhang Xu
Shuhang Xu
Endocrine and Diabetes Center, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
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ablation was performed to fully cover the whole thyroid nodule. In the EA group, after cystic fluid was aspirated, 98% alcohol was injected into the thyroid nodule under the guidance of ultrasound for three times of irrigation. Absolute alcohol
Yuntao Song
Yuntao Song
Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education/Beijing, Department of Head and Neck Surgery, Peking University Cancer Hospital and Institute, Beijing, China
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Jiaxin Wang
Jiaxin Wang
Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education/Beijing, Department of Head and Neck Surgery, Peking University Cancer Hospital and Institute, Beijing, China
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Yanli Zhu
Yanli Zhu
Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education/Beijing, Department of Pathology, Peking University Cancer Hospital and Institute, Beijing, China
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Guohui Xu
Guohui Xu
Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education/Beijing, Department of Head and Neck Surgery, Peking University Cancer Hospital and Institute, Beijing, China
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Tianxiao Wang
Tianxiao Wang
Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education/Beijing, Department of Head and Neck Surgery, Peking University Cancer Hospital and Institute, Beijing, China
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Bin Zhang
Bin Zhang
Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education/Beijing, Department of Head and Neck Surgery, Peking University Cancer Hospital and Institute, Beijing, China
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), regardless of tumor size ( 5 ). Recently published randomized controlled trials found no benefit of prophylactic CND on locoregional or biochemical recurrence in patients with clinically free central LNs but confirmed a higher risk of permanent
