Zheng Chen
Zheng Chen
Department of Endocrinology and Metabolism, The Second Affiliated Hospital of Nanchang University, Nanchang, China
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Haixia Zeng
Haixia Zeng
Department of Endocrinology and Metabolism, The Second Affiliated Hospital of Nanchang University, Nanchang, China
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Qiulan Huang
Qiulan Huang
Department of Endocrinology and Metabolism, The Second Affiliated Hospital of Nanchang University, Nanchang, China
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Cuiping Lin
Cuiping Lin
Department of Endocrinology and Metabolism, The Second Affiliated Hospital of Nanchang University, Nanchang, China
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Xuan Li
Xuan Li
Department of Endocrinology and Metabolism, The Second Affiliated Hospital of Nanchang University, Nanchang, China
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Shaohua Sun
Shaohua Sun
Department of Endocrinology and Metabolism, The Second Affiliated Hospital of Nanchang University, Nanchang, China
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Jian-ping Liu
Jian-ping Liu
Department of Endocrinology and Metabolism, The Second Affiliated Hospital of Nanchang University, Nanchang, China
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tumors, such as breast, prostate, and lung cancers; hence, CLU overexpression may serve as a prognostic biomarker for aggressive tumors, and CLU inhibition may be an effective treatment to reduce metastasis risk and increase tumor sensitivity to
Panagiotis Anagnostis
Panagiotis Anagnostis
Unit of Reproductive Endocrinology, 1st Department of Obstetrics and Gynecology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece
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Irene Lambrinoudaki
Irene Lambrinoudaki
2nd Department of Obstetrics and Gynecology, National and Kapodistrian University of Athens, Medical School, Athens, Greece
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John C Stevenson
John C Stevenson
National Heart and Lung Institute, Imperial College London, Royal Brompton and Harefield Hospitals, Guy’s and St Thomas’ NHS Foundation Trust, London, UK
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Dimitrios G Goulis
Dimitrios G Goulis
Unit of Reproductive Endocrinology, 1st Department of Obstetrics and Gynecology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece
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disorders (thyroid dysfunction) augment CVD risk in women around menopause ( 2 ). Whether this increased risk is translated into an equivalent risk of CVD events in postmenopausal women, irrespective of the effect of chronological aging, has not been
Christos Tsatsanis
Christos Tsatsanis
Department of Clinical Chemistry, School of Medicine, University of Crete, Heraklion, Crete, Greece
Molecular Reproductive Research Group, Department of Translational Medicine, Lund University, Malmö, Sweden
Institute of Molecular Biology and Biotechnology, FORTH, Heraklion, Greece
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Molecular Reproductive Research Group, Department of Translational Medicine, Lund University, Malmö, Sweden
Institute of Molecular Biology and Biotechnology, FORTH, Heraklion, Greece
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Angel Elenkov
Angel Elenkov
Molecular Reproductive Research Group, Department of Translational Medicine, Lund University, Malmö, Sweden
Reproductive Medicine Centre, Skåne University Hospital Malmö, Malmö, Sweden
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Reproductive Medicine Centre, Skåne University Hospital Malmö, Malmö, Sweden
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Irene Leijonhufvud
Irene Leijonhufvud
Reproductive Medicine Centre, Skåne University Hospital Malmö, Malmö, Sweden
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Katerina Vaporidi
Katerina Vaporidi
Molecular Reproductive Research Group, Department of Translational Medicine, Lund University, Malmö, Sweden
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Åsa Tivesten
Åsa Tivesten
Wallenberg Laboratory for Cardiovascular and Metabolic Research, Institute of Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
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Aleksander Giwercman
Aleksander Giwercman
Molecular Reproductive Research Group, Department of Translational Medicine, Lund University, Malmö, Sweden
Reproductive Medicine Centre, Skåne University Hospital Malmö, Malmö, Sweden
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Reproductive Medicine Centre, Skåne University Hospital Malmö, Malmö, Sweden
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; TM, transgender men; TSH, thyroid-stimulating hormone; TW, transgender women. A group of 30 age-matched healthy CM and 26 age-matched healthy CW was also included in the study as control comparison groups. They were recruited among healthy
Małgorzata Kałużna
Małgorzata Kałużna
Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland
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Pola Kompf
Pola Kompf
Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland
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Katarzyna Wachowiak-Ochmańska
Katarzyna Wachowiak-Ochmańska
Heliodor Święcicki Clinical Hospital, Poznan, Poland
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Jerzy Moczko
Jerzy Moczko
Department of Computer Science and Statistics, Poznan University of Medical Sciences, Poznan, Poland
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Aleksandra Królczyk
Aleksandra Królczyk
Chair and Department of Gastroenterology, Dietetics and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland
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Adam Janicki
Adam Janicki
Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland
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Karol Szapel
Karol Szapel
Department of Physiotherapy, Poznan University of Medical Sciences, Poznan, Poland
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Marian Grzymisławski
Marian Grzymisławski
Chair and Department of Gastroenterology, Dietetics and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland
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Marek Ruchała
Marek Ruchała
Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland
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Katarzyna Ziemnicka
Katarzyna Ziemnicka
Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland
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of an infection preceding symptoms or exposure to medications causing similar GI disturbances. Patients’ family history of IBS, celiac disease and colorectal cancer should also be assessed ( 9 ). The fluctuating nature of the IBS and lack of a
Mette Bøgehave
Mette Bøgehave
Department of Clinical Biochemistry, Hospital South West Jutland, University Hospital of Southern Denmark, Esbjerg, Denmark
Unit for Thrombosis Research, Department of Regional Health Research, University of Southern Denmark, Denmark
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Unit for Thrombosis Research, Department of Regional Health Research, University of Southern Denmark, Denmark
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Dorte Glintborg
Dorte Glintborg
Department of Endocrinology, Odense University Hospital, Odense, Denmark
Department of Clinical Research, University of Southern Denmark, Odense, Denmark
OPEN, Open Patient data Explorative Network, Odense University Hospital, Region of Southern Denmark, Odense, Denmark
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Department of Clinical Research, University of Southern Denmark, Odense, Denmark
OPEN, Open Patient data Explorative Network, Odense University Hospital, Region of Southern Denmark, Odense, Denmark
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Jørgen Brodersen Gram
Jørgen Brodersen Gram
Department of Clinical Biochemistry, Hospital South West Jutland, University Hospital of Southern Denmark, Esbjerg, Denmark
Unit for Thrombosis Research, Department of Regional Health Research, University of Southern Denmark, Denmark
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Unit for Thrombosis Research, Department of Regional Health Research, University of Southern Denmark, Denmark
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Else-Marie Bladbjerg
Else-Marie Bladbjerg
Department of Clinical Biochemistry, Hospital South West Jutland, University Hospital of Southern Denmark, Esbjerg, Denmark
Unit for Thrombosis Research, Department of Regional Health Research, University of Southern Denmark, Denmark
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Unit for Thrombosis Research, Department of Regional Health Research, University of Southern Denmark, Denmark
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Marianne Skovsager Andersen
Marianne Skovsager Andersen
Department of Endocrinology, Odense University Hospital, Odense, Denmark
Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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Johannes Jakobsen Sidelmann
Johannes Jakobsen Sidelmann
Department of Clinical Biochemistry, Hospital South West Jutland, University Hospital of Southern Denmark, Esbjerg, Denmark
Unit for Thrombosis Research, Department of Regional Health Research, University of Southern Denmark, Denmark
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Unit for Thrombosis Research, Department of Regional Health Research, University of Southern Denmark, Denmark
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Introduction Opioid medications are widely used to treat chronic non-cancer pain ( 1 ). Male hypogonadism, characterized by low concentrations of testosterone and luteinizing hormone (LH), is one of the most well-described hormonal adverse
Alan D Rogol
Alan D Rogol
Department of Pediatrics, University of Virginia, Charlottesville, Virginia, USA
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thyroid disease ( 49 ). Davis and colleagues measured AMH levels, a marker of ovarian reserve for it reflects the primordial follicle pool ( 43 ). It is produced by the granulosa cells of the maturing follicles and thus is an index of the remaining
Yan-yu Zhang
Yan-yu Zhang
Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China
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Xian Zhang
Xian Zhang
Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China
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Shao-yang Bu
Shao-yang Bu
Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China
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Wei-wei Zhang
Wei-wei Zhang
Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China
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Tian-xiu Li
Tian-xiu Li
Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China
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De-cai Zheng
De-cai Zheng
Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China
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Ze-xiang Huang
Ze-xiang Huang
Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China
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Qian Wang
Qian Wang
Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China
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teleosts ( 3 ). Furthermore, kisspeptin system is also involved in modulating certain cancers and vascular dynamics ( 4 ). Kisspeptin is encoded by one gene ( KISS1 / Kiss1 ) in mammals, whereas two paralogous genes, kiss1 and kiss2 , have been
Veronica Astro
Veronica Astro
Biological and Environmental Science and Engineering Division, King Abdullah University of Science and Technology, Thuwal, Saudi Arabia
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Elisabetta Fiacco
Elisabetta Fiacco
Biological and Environmental Science and Engineering Division, King Abdullah University of Science and Technology, Thuwal, Saudi Arabia
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Kelly Johanna Cardona-Londoño
Kelly Johanna Cardona-Londoño
Biological and Environmental Science and Engineering Division, King Abdullah University of Science and Technology, Thuwal, Saudi Arabia
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Ilario De Toma
Ilario De Toma
Sequentia Biotech SL, Barcelona, Spain
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Hams Saeed Alzahrani
Hams Saeed Alzahrani
Department of Genetic Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
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Jumana Alama
Jumana Alama
Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia
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Amal Kokandi
Amal Kokandi
Department of Dermatology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
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Taha Abo-Almagd Abdel-Meguid Hamoda
Taha Abo-Almagd Abdel-Meguid Hamoda
Department of Urology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
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Majed Felemban
Majed Felemban
Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia
Center of Innovation in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
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Center of Innovation in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
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Antonio Adamo
Antonio Adamo
Biological and Environmental Science and Engineering Division, King Abdullah University of Science and Technology, Thuwal, Saudi Arabia
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developing cardiac abnormalities, metabolic disorders, type-2 diabetes, osteoporosis, and cancers ( 9 ). Despite being a highly prevalent chromosomal male aneuploidy, there is still a significant gap in knowledge about treatments, care management of patients
Xinyuan Zhang
Xinyuan Zhang
Laboratory of Genetic Disease and Perinatal Medicine, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China
School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, Sichuan, China
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School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, Sichuan, China
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Suiyan Li
Suiyan Li
School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, Sichuan, China
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Hongwei Liu
Hongwei Liu
Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China
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Huai Bai
Huai Bai
Laboratory of Genetic Disease and Perinatal Medicine, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China
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Qingqing Liu
Qingqing Liu
Laboratory of Genetic Disease and Perinatal Medicine, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China
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Chunyi Yang
Chunyi Yang
Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China
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Ping Fan
Ping Fan
Laboratory of Genetic Disease and Perinatal Medicine, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China
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resistance, heightened oxidative stress, low-grade chronic inflammation, dyslipidemia, increased risks of complications during pregnancy, type 2 diabetes, cardiocerebrovascular disease, anxiety and depression, obstructive sleep apnea, and endometrial cancer
