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Clinical Research Centre, Medical University of Bialystok, Bialystok, Poland
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-to-severe GO ( 21 , 22 , 23 ). Lastly, a second course of ivGC treatment or teleradiotherapy in combination with i.v. or oral steroids may be of benefit in selected patients as a second line of therapy. Nevertheless, studies provide only limited evidence to
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. detected a circRNA expression profile in serum exosomes from GD patients, which implicated hsa_circRNA_000102 in the development of GD via a virus infection signalling pathway ( 9 ). To date, the functions of other circRNAs in GD remain unclear, and more
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the true increase of PTC incidence ( 3 ). Although the mortality rate of PTC is very low ( 4 ), its prognostic factors deserve attention because of the large population base of incidence. 25(OH)D, a kind of steroid hormone mainly produced in skin
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GO group. We excluded all patients treated with steroids, thyroid surgery, or radiotherapy from the present study. Patients were diagnosed with GO based upon European Group on Graves’ Orbitopathy (EUGOGO) Guidelines, with GO CAS scores being evaluated
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Department of Endocrinology, The Affiliated Hospital of Guilin Medical University, Guilin, China
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that this is related to the difference in muscle reserve caused by the different sex hormone profiles of men and women, as well as a greater frequency of moderate to intense physical activity by males than by females in the long term. Harman et al
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patients scored significantly higher on the depression subscale of the Profile of Mood States (POMS) as opposed to negligible to mild GO patients ( 80 ). However, no significant difference in GO severity was noted regarding the anxiety subscale of the POMS