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Division of Endocrinology and Metabolism, Department of Medicine, Georgetown University, Washington, District of Columbia, USA
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Introduction Diurnal variations in the serum concentration of steroid hormones and their metabolism, as assessed by urinary excretion, have long been known for cortisol and testosterone ( 1 , 2 , 3 ). Less information exists for the other up
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that can increase the incidence as well as tumor aggressiveness ( 8 , 9 , 10 ). Sexual steroid hormones acting through their receptors regulate signaling pathways related to cell proliferation, epithelial–mesenchymal transition, apoptosis, cell
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KORA Study Centre, University Hospital of Augsburg, Augsburg, Augsburg, Germany
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German Centre for Cardiovascular Research (DZHK), Partner site Munich Heart Alliance, Munich, Germany
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German Heart Centre Munich, Technical University of Munich, Munich, Germany
Institute of Epidemiology and Medical Biometry, University of Ulm, Ulm, Germany
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German Centre for Cardiovascular Research (DZHK), Partner Site Hamburg/Kiel/Lübeck, Hamburg, Germany
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Introduction Steroid hormones are signaling molecules involved in regulation of electrolyte concentrations, blood pressure, reproductive functions, and metabolism ( 1 ). A lack or an excess of steroids results from enzyme defects, adenomas, or
Department of Medical Sciences, Occupational and Environmental Medicine, Uppsala University, Uppsala, Sweden
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ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, Utah, USA
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Department of Chemistry – BMC, Analytical Chemistry, Uppsala University, Uppsala, Sweden
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are very few studies aimed on measurement of bioactive sex hormones and their precursors in elderly apparently healthy individuals ( 21 ) and individuals with pathology ( 22 , 23 ). Accurate quantification of the low concentrations of sex steroids
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. The art of measuring steroids: principles and practice of current hormonal steroid analysis . Journal of Steroid Biochemistry and Molecular Biology 2018 179 88 – 103 . ( https://doi.org/10.1016/j.jsbmb.2017.09.003 ) 25 Mosteller RD Simplified
Sahlgrenska Osteoporosis Centre, Center for Bone and Arthritis Research (CBAR), Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden
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Sahlgrenska Osteoporosis Centre, Center for Bone and Arthritis Research (CBAR), Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden
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Sahlgrenska Osteoporosis Centre, Center for Bone and Arthritis Research (CBAR), Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden
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Department of Endocrinology, Skaraborg Central Hospital, Skövde, Sweden
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Introduction Sex steroid hormones are predominantly produced from cholesterol by the gonads and the adrenal glands. Then, the sex steroids are distributed to target tissues through the circulation. In addition, many tissues and organs
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regulation of precursors of androgens and other steroid hormones within the steroid metabolome encompassing glucocorticoids, mineralocorticoids and estrogens is largely unknown in PCOS. Although PCOS has frequently been reported in adolescents, the
Department of Pediatrics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Reproduction & Development Research Institute, de Boelelaan, Amsterdam, The Netherlands
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Department of Pediatrics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Reproduction & Development Research Institute, de Boelelaan, Amsterdam, The Netherlands
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Department of Pediatrics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Reproduction & Development Research Institute, de Boelelaan, Amsterdam, The Netherlands
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and thawed only once just before analysis. After placement in a salivette, the pad was centrifuged at 1900 g for 5 min, enabling the extraction of urine. Urinary steroids were determined using quantitative data produced by gas chromatography
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Division of Medicine, Akershus University Hospital, Lørenskog, Norway
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Department of Clinical Medicine, University of Bergen, Bergen, Norway
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K.G. Jebsen-Center for Autoimmune Diseases, University of Bergen, Bergen, Norway
Department of Medicine, Haukeland University Hospital, Bergen, Norway
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K.G. Jebsen-Center for Autoimmune Diseases, University of Bergen, Bergen, Norway
Department of Medicine, Haukeland University Hospital, Bergen, Norway
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(CAH due to steroid 21-hydroxylase deficiency) consistently timed hormone measurements relative to medication schedule and time of day is recommended ( 1 ). Drug fasting morning values of androstenedione and testosterone should be in the normal range
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better ratio of muscle growth vs side effects. Although this claim is far from being supported by clinical trials, SARMs are promoted as a safer, albeit more expensive, alternative to steroidal androgens. Thyroid hormone, clenbuterol and dinitrophenol