Beijing Key Laboratory of Diabetes Research and Care, Beijing, China
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Beijing Key Laboratory of Diabetes Research and Care, Beijing, China
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Beijing Key Laboratory of Diabetes Research and Care, Beijing, China
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Beijing Key Laboratory of Diabetes Research and Care, Beijing, China
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Beijing Key Laboratory of Diabetes Research and Care, Beijing, China
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Beijing Key Laboratory of Diabetes Research and Care, Beijing, China
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Beijing Key Laboratory of Diabetes Research and Care, Beijing, China
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antioxidant property ( 7 ). Hyperuricemia (HUA) is defined as the level of serum uric acid (sUA) >6.0 mg/dL (>360 µmol/L) for females and >7.0 mg/dL (>420 µmol/L) for males ( 8 ). Elevated sUA levels may lead to the deposition of urate crystals in the joints
Laboratory of Diabetic Kidney Disease, Centre of Diabetes and Metabolism Research, West China Hospital of Sichuan University, Chengdu, Sichuan, China
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Laboratory of Diabetic Kidney Disease, Centre of Diabetes and Metabolism Research, West China Hospital of Sichuan University, Chengdu, Sichuan, China
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Laboratory of Diabetic Kidney Disease, Centre of Diabetes and Metabolism Research, West China Hospital of Sichuan University, Chengdu, Sichuan, China
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Laboratory of Diabetic Kidney Disease, Centre of Diabetes and Metabolism Research, West China Hospital of Sichuan University, Chengdu, Sichuan, China
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Laboratory of Diabetic Kidney Disease, Centre of Diabetes and Metabolism Research, West China Hospital of Sichuan University, Chengdu, Sichuan, China
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Laboratory of Diabetic Kidney Disease, Centre of Diabetes and Metabolism Research, West China Hospital of Sichuan University, Chengdu, Sichuan, China
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Laboratory of Diabetic Kidney Disease, Centre of Diabetes and Metabolism Research, West China Hospital of Sichuan University, Chengdu, Sichuan, China
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Laboratory of Diabetic Kidney Disease, Centre of Diabetes and Metabolism Research, West China Hospital of Sichuan University, Chengdu, Sichuan, China
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Laboratory of Diabetic Kidney Disease, Centre of Diabetes and Metabolism Research, West China Hospital of Sichuan University, Chengdu, Sichuan, China
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Laboratory of Diabetic Kidney Disease, Centre of Diabetes and Metabolism Research, West China Hospital of Sichuan University, Chengdu, Sichuan, China
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Laboratory of Diabetic Kidney Disease, Centre of Diabetes and Metabolism Research, West China Hospital of Sichuan University, Chengdu, Sichuan, China
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Centre of Diabetes and Metabolism Research, West China Hospital of Sichuan University, Chengdu, Sichuan, China
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Laboratory of Diabetic Kidney Disease, Centre of Diabetes and Metabolism Research, West China Hospital of Sichuan University, Chengdu, Sichuan, China
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the last decade. In China Kidney Disease Network 2015 annual data report, diabetes-related kidney disease is now the leading cause of chronic kidney disease (CKD), accounting for 26.96% ( 2 ). Serum uric acid (SUA) level has been widely recognized as
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mechanisms mainly include metformin, thiazolidinediones (TZDs) α-glucosidase inhibitors, and sodium–glucose cotransporter 2 inhibitors (SGLT2i). The formation of serum uric acid (SUA) is the ribose 5-phosphate, a pentose derived from glycidic metabolism
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Section Endocrinology, Department of Medicine, Erasmus MC, Rotterdam, The Netherlands
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Borghi C . Serum uric acid predicts incident metabolic syndrome in the elderly in an analysis of the Brisighella Heart Study . Scientific Reports 2018 8 11529 . 10.1038/s41598-018-29955-w 18 Herder C Karakas M Koenig W . Biomarkers for
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using the Mann–Whitney U test. PSM was used to balance possible confounders between patients with APA and patients with IHA. Clinical variables including age, sex, serum calcium, phosphate, blood urea nitrogen, creatinine, and uric acid were included
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-density lipoprotein cholesterol (HDL-C) measurements were performed by lipid spectroscopy. Uric acid level was determined by uricase. Fasting insulin, thyroid-stimulating hormone (TSH), free T3 (FT3), and free T4 (FT4) levels were detected by electrochemiluminescence
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Department of Clinical Research Center, The First People's Hospital of Xiaoshan District, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, China
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doctor to have diabetes or with a HbA1c ≥6.5%), total protein, blood urea nitrogen, serum uric acid, serum phosphorus, and serum calcium levels, as continuous variables; and gender, race, educational level, moderate recreational activities, and smoked at
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Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway
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Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway
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Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway
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added as a sweetening ingredient. Human studies and animal models have demonstrated that fructose increases serum uric acid levels (12, 13) . A rise in uric acid levels inhibits nitric oxide availability (13) . Because insulin requires nitric oxide to
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Department of Endocrinology, The First Hospital of Lanzhou University, Lanzhou, Gansu, China
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Department of Endocrinology, The First Hospital of Lanzhou University, Lanzhou, Gansu, China
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Department of Endocrinology, The First Hospital of Lanzhou University, Lanzhou, Gansu, China
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hemoglobin concentration; RBC count, red blood cell count; SBP, systolic blood pressure; TBil, total bilirubin; TC, total cholesterol; TG, triglyceride; TP, total protein; UA, uric acid; VB12, vitamin B12. Comparison of serum ferritin and the
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Division of Endocrinology and Metabolism, Diabetes Center, Kurume Medical Center, Kokubu-machi, Kurume-city, Fukuoka, Japan
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Division of Endocrinology and Metabolism, Diabetes Center, Kurume Medical Center, Kokubu-machi, Kurume-city, Fukuoka, Japan
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composition, glucose metabolism, serum uric acid and lipid metabolism, and urinary glucose excretion, did not show any significant correlations with the log GIR ( Table 2 ). Table 1 Baseline participant characteristics ( n = 20). Variables