Search Results

You are looking at 1 - 10 of 65 items for :

  • secondary sexual characteristics x
Clear All
Rui-yi Tang Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing, People’s Republic of China

Search for other papers by Rui-yi Tang in
Google Scholar
PubMed
Close
,
Rong Chen Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing, People’s Republic of China

Search for other papers by Rong Chen in
Google Scholar
PubMed
Close
,
Miao Ma Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing, People’s Republic of China

Search for other papers by Miao Ma in
Google Scholar
PubMed
Close
,
Shou-qing Lin Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing, People’s Republic of China

Search for other papers by Shou-qing Lin in
Google Scholar
PubMed
Close
,
Yi-wen Zhang Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing, People’s Republic of China

Search for other papers by Yi-wen Zhang in
Google Scholar
PubMed
Close
, and
Ya-ping Wang Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing, People’s Republic of China

Search for other papers by Ya-ping Wang in
Google Scholar
PubMed
Close

as kg/m 2 . The Tanner score was used to assess baseline secondary sexual characteristics. Because our centre is a tertiary hospital, many patients were referred to our hospital after having received some hormone treatment. Information regarding

Open access
Nandini Shankara Narayana Andrology Department, Concord Hospital and, ANZAC Research Institute, University of Sydney, Sydney, Australia

Search for other papers by Nandini Shankara Narayana in
Google Scholar
PubMed
Close
,
Lam P Ly Andrology Department, Concord Hospital and, ANZAC Research Institute, University of Sydney, Sydney, Australia

Search for other papers by Lam P Ly in
Google Scholar
PubMed
Close
,
Veena Jayadev Andrology Department, Concord Hospital and, ANZAC Research Institute, University of Sydney, Sydney, Australia

Search for other papers by Veena Jayadev in
Google Scholar
PubMed
Close
,
Carolyn Fennell Andrology Department, Concord Hospital and, ANZAC Research Institute, University of Sydney, Sydney, Australia

Search for other papers by Carolyn Fennell in
Google Scholar
PubMed
Close
,
Sasha Savkovic Andrology Department, Concord Hospital and, ANZAC Research Institute, University of Sydney, Sydney, Australia

Search for other papers by Sasha Savkovic in
Google Scholar
PubMed
Close
,
Ann J Conway Andrology Department, Concord Hospital and, ANZAC Research Institute, University of Sydney, Sydney, Australia

Search for other papers by Ann J Conway in
Google Scholar
PubMed
Close
, and
David J Handelsman Andrology Department, Concord Hospital and, ANZAC Research Institute, University of Sydney, Sydney, Australia

Search for other papers by David J Handelsman in
Google Scholar
PubMed
Close

sexual characteristics in males with hypogonadotropic hypogonadism . Journal of Sexual Medicine 2011 8 3471 – 3478 .

Open access
Rafaella Sales de Freitas Departamento de Psicobiologia, Universidade Federal de São Paulo, São Paulo, Brazil

Search for other papers by Rafaella Sales de Freitas in
Google Scholar
PubMed
Close
,
Thiago F A França Departamento de Psicobiologia, Universidade Federal de São Paulo, São Paulo, Brazil

Search for other papers by Thiago F A França in
Google Scholar
PubMed
Close
, and
Sabine Pompeia Departamento de Psicobiologia, Universidade Federal de São Paulo, São Paulo, Brazil

Search for other papers by Sabine Pompeia in
Google Scholar
PubMed
Close

involves neuroendocrine changes leading to maturation of the gonads, acceleration of growth in height, and development of secondary sexual characteristics. The kisspeptin peptides, produced by small groups of neurons in the hypothalamus, play a key role in

Open access
M Jensterle Department of Endocrinology, Diabetes and Metabolic Diseases, University Medical Centre Ljubljana, Ljubljana, Slovenia

Search for other papers by M Jensterle in
Google Scholar
PubMed
Close
,
A Podbregar University Rehabilitation Institute Republic of Slovenia, Ljubljana, Slovenia

Search for other papers by A Podbregar in
Google Scholar
PubMed
Close
,
K Goricar University of Ljubljana, Faculty of Medicine, Institute of Biochemistry, Pharmacogenetics Laboratory, Ljubljana, Slovenia

Search for other papers by K Goricar in
Google Scholar
PubMed
Close
,
N Gregoric Department of Endocrinology, Diabetes and Metabolic Diseases, University Medical Centre Ljubljana, Ljubljana, Slovenia

Search for other papers by N Gregoric in
Google Scholar
PubMed
Close
, and
A Janez Department of Endocrinology, Diabetes and Metabolic Diseases, University Medical Centre Ljubljana, Ljubljana, Slovenia

Search for other papers by A Janez in
Google Scholar
PubMed
Close

been poor responders to LSM, by means of reversal of FH and WR. The primary outcome measures were changes in testosterone, sexual function and gonadotropins. The secondary outcomes were measures of obesity and metabolic profile. Materials and

Open access
Yanfei Chen Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China

Search for other papers by Yanfei Chen in
Google Scholar
PubMed
Close
,
Mei Li Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China

Search for other papers by Mei Li in
Google Scholar
PubMed
Close
,
Binrong Liao Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China

Search for other papers by Binrong Liao in
Google Scholar
PubMed
Close
,
Jingzi Zhong Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China

Search for other papers by Jingzi Zhong in
Google Scholar
PubMed
Close
, and
Dan Lan Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China

Search for other papers by Dan Lan in
Google Scholar
PubMed
Close

development of internal and external reproductive organs and secondary sexual characteristics before the age of 8 in girls and 9 in boys ( 1 ). In recent years, the age of puberty initiation has been declining all over the world, paralleled by the increasing

Open access
Mei Li Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China

Search for other papers by Mei Li in
Google Scholar
PubMed
Close
,
Yanfei Chen Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China

Search for other papers by Yanfei Chen in
Google Scholar
PubMed
Close
,
Binrong Liao Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China

Search for other papers by Binrong Liao in
Google Scholar
PubMed
Close
,
Jing Tang Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China

Search for other papers by Jing Tang in
Google Scholar
PubMed
Close
,
Jingzi Zhong Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China

Search for other papers by Jingzi Zhong in
Google Scholar
PubMed
Close
, and
Dan Lan Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China

Search for other papers by Dan Lan in
Google Scholar
PubMed
Close

luteinizing hormone (LH) and follicle stimulating hormone (FSH). Central precocious puberty (CPP) is a common pediatric endocrine disease due to premature reactivation of the HPG axis leading to the development of secondary sexual characteristics before the

Open access
Anne Bachelot Department of Endocrinology and Reproductive Medicine and Centre de Référence des Maladies Endocriniennes Rares de la croissance et Centre des Pathologies gynécologiques Rares, AP-HP, IE3M, Hôpital Pitié-Salpêtrière, ICAN, Paris, France
UPMC Univ, Paris, France

Search for other papers by Anne Bachelot in
Google Scholar
PubMed
Close
,
Magaly Vialon Department of Endocrinology and Reproductive Medicine and Centre de Référence des Maladies Endocriniennes Rares de la croissance et Centre des Pathologies gynécologiques Rares, AP-HP, IE3M, Hôpital Pitié-Salpêtrière, ICAN, Paris, France

Search for other papers by Magaly Vialon in
Google Scholar
PubMed
Close
,
Amandine Baptiste AP-HP, Clinical Research Unit Paris Descartes Necker Cochin, Paris, France

Search for other papers by Amandine Baptiste in
Google Scholar
PubMed
Close
,
Isabelle Tejedor Department of Endocrinology and Reproductive Medicine and Centre de Référence des Maladies Endocriniennes Rares de la croissance et Centre des Pathologies gynécologiques Rares, AP-HP, IE3M, Hôpital Pitié-Salpêtrière, ICAN, Paris, France

Search for other papers by Isabelle Tejedor in
Google Scholar
PubMed
Close
,
Caroline Elie AP-HP, Clinical Research Unit Paris Descartes Necker Cochin, Paris, France

Search for other papers by Caroline Elie in
Google Scholar
PubMed
Close
,
Michel Polak Department of Pediatric Endocrinology, Gynecology and Diabetology, Centre de Référence des Maladies Endocriniennes Rares de la Croissance et Centre des pathologies gynécologiques Rares, Hôpital Universitaire Necker Enfants malades, Paris, France
Université Paris Descartes, Paris, France

Search for other papers by Michel Polak in
Google Scholar
PubMed
Close
,
Philippe Touraine Department of Endocrinology and Reproductive Medicine and Centre de Référence des Maladies Endocriniennes Rares de la croissance et Centre des Pathologies gynécologiques Rares, AP-HP, IE3M, Hôpital Pitié-Salpêtrière, ICAN, Paris, France
UPMC Univ, Paris, France

Search for other papers by Philippe Touraine in
Google Scholar
PubMed
Close
, and
the CRMERC study group
Search for other papers by the CRMERC study group in
Google Scholar
PubMed
Close

). Once growth is no longer a concern, a shift in treatment goals from optimization of growth and puberty to prevention of long-term adverse outcomes and optimization of fertility and sexual function is needed ( 5 , 6 , 7 , 8 , 9 , 10 ). The

Open access
Shota Dzemaili University of Lausanne, Institute of Higher Education and Research in Healthcare, Lausanne, Switzerland

Search for other papers by Shota Dzemaili in
Google Scholar
PubMed
Close
,
Jitske Tiemensma University of California Merced, Psychological Science, Merced, CA, USA

Search for other papers by Jitske Tiemensma in
Google Scholar
PubMed
Close
,
Richard Quinton Department of Endocrinology, Institute for Human Genetics, University of Newcastle-upon-Tyne, Newcastle-upon-Tyne, United Kingdom

Search for other papers by Richard Quinton in
Google Scholar
PubMed
Close
,
Nelly Pitteloud Endocrinology, Diabetes & Metabolism Service of the Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland

Search for other papers by Nelly Pitteloud in
Google Scholar
PubMed
Close
,
Diane Morin University of Lausanne, Institute of Higher Education and Research in Healthcare, Lausanne, Switzerland
Faculty of Nursing Science, Laval University, Québec City, Canada

Search for other papers by Diane Morin in
Google Scholar
PubMed
Close
, and
Andrew A Dwyer University of Lausanne, Institute of Higher Education and Research in Healthcare, Lausanne, Switzerland
Endocrinology, Diabetes & Metabolism Service of the Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland

Search for other papers by Andrew A Dwyer in
Google Scholar
PubMed
Close

induce secondary sexual characteristics and menses ( 4 ). Combined gonadotropin therapy or physiologic treatment with pulsatile GnRH are equally effective for inducing fertility in the vast majority of cases ( 10 ). Compared to fertile counterparts

Open access
María J Gómora Departamento de Embriología, Facultad de Medicina, Universidad Nacional Autónoma de México, CdMx, Mexico

Search for other papers by María J Gómora in
Google Scholar
PubMed
Close
,
Flavia Morales-Vásquez Departamento de Oncología Médica, Instituto Nacional de Cancerología, Secretaría de Salud de México, CdMx, Mexico

Search for other papers by Flavia Morales-Vásquez in
Google Scholar
PubMed
Close
,
Enrique Pedernera Departamento de Embriología, Facultad de Medicina, Universidad Nacional Autónoma de México, CdMx, Mexico

Search for other papers by Enrique Pedernera in
Google Scholar
PubMed
Close
,
Delia Perez-Montiel Departamento de Patología, Instituto Nacional de Cancerología, Secretaría de Salud de México, CdMx, Mexico

Search for other papers by Delia Perez-Montiel in
Google Scholar
PubMed
Close
,
Horacio López-Basave Departamento de Cirugía Oncológica, Instituto Nacional de Cancerología, Secretaría de Salud de México, CdMx, Mexico

Search for other papers by Horacio López-Basave in
Google Scholar
PubMed
Close
,
Antonio R Villa División de Investigación, Facultad de Medicina, Universidad Nacional Autónoma de México, CdMx, Mexico

Search for other papers by Antonio R Villa in
Google Scholar
PubMed
Close
,
Azucena Hernández-Martínez Hospital Militar de Especialidades de la Mujer y Neonatología, Secretaría de la Defensa Nacional, CdMx, Mexico

Search for other papers by Azucena Hernández-Martínez in
Google Scholar
PubMed
Close
,
Esteban Mena Unidad de Apoyo Académico, Secretaría General, Facultad de Medicina, Universidad Nacional Autónoma de México, CdMx, Mexico

Search for other papers by Esteban Mena in
Google Scholar
PubMed
Close
, and
Carmen Mendez Departamento de Embriología, Facultad de Medicina, Universidad Nacional Autónoma de México, CdMx, Mexico

Search for other papers by Carmen Mendez in
Google Scholar
PubMed
Close

that can increase the incidence as well as tumor aggressiveness ( 8 , 9 , 10 ). Sexual steroid hormones acting through their receptors regulate signaling pathways related to cell proliferation, epithelial–mesenchymal transition, apoptosis, cell

Open access
Lachlan Angus Department of Medicine (Austin Health), The University of Melbourne, Heidelberg, Victoria, Australia

Search for other papers by Lachlan Angus in
Google Scholar
PubMed
Close
,
Shalem Leemaqz Robinson Research Institute, Adelaide Medical School, The University of Adelaide, Adelaide, South Australia

Search for other papers by Shalem Leemaqz in
Google Scholar
PubMed
Close
,
Olivia Ooi Department of Medicine (Austin Health), The University of Melbourne, Heidelberg, Victoria, Australia

Search for other papers by Olivia Ooi in
Google Scholar
PubMed
Close
,
Pauline Cundill Equinox Gender Diverse Clinic, Thorne Harbour Health, Fitzroy, Victoria, Australia

Search for other papers by Pauline Cundill in
Google Scholar
PubMed
Close
,
Nicholas Silberstein Equinox Gender Diverse Clinic, Thorne Harbour Health, Fitzroy, Victoria, Australia

Search for other papers by Nicholas Silberstein in
Google Scholar
PubMed
Close
,
Peter Locke Equinox Gender Diverse Clinic, Thorne Harbour Health, Fitzroy, Victoria, Australia

Search for other papers by Peter Locke in
Google Scholar
PubMed
Close
,
Jeffrey D Zajac Department of Medicine (Austin Health), The University of Melbourne, Heidelberg, Victoria, Australia

Search for other papers by Jeffrey D Zajac in
Google Scholar
PubMed
Close
, and
Ada S Cheung Department of Medicine (Austin Health), The University of Melbourne, Heidelberg, Victoria, Australia

Search for other papers by Ada S Cheung in
Google Scholar
PubMed
Close

. Over 3–24 months, this leads to feminine physical characteristics including softening of skin, a decrease in facial and body hair growth, changes in body fat and muscle distribution, as well as breast development ( 4 ). Oestradiol improves psychological

Open access