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K G Samsom, L M van Veenendaal, G D Valk, M R Vriens, M E T Tesselaar, and J G van den Berg

provide an up to date overview of the current literature regarding prognostic molecular factors in SI-NETs for clinicians treating patients with SI-NETs, we did not aim to perform a formal systematic review. The domain of this search consisted of adult

Open access

David T Broome, Gauri B Gadre, Ehsan Fayazzadeh, James F Bena, and Christian Nasr

Discussion This study aimed to evaluate the impact of pleural effusion on OS and CSS in patients with FDTC and distant metastases and compare this novel risk factor to other well-known prognostic variables. This is the first study to investigate pleural

Open access

June Young Choi, Jin Wook Yi, Jun Hyup Lee, Ra-Yeong Song, Hyeongwon Yu, Hyungju Kwon, Young Jun Chai, Su-jin Kim, and Kyu Eun Lee

and prognostic factors of PTC using ‘The Cancer Genome Atlas’ (TCGA) data. TCGA kindly provides multiplatform genomics data such as sequence and read count data from next-generation sequencing, copy-number analysis, methylomics and proteomics data ( 10

Open access

Malgorzata Fuksiewicz, Maria Kowalska, Agnieszka Kolasinska-Cwikla, and Beata Kotowicz

prostate cancer may be associated with a component of neuroendocrine cells in adenocarcinoma or with the initiated process of transformation of cancer cells in the neuroendocrine direction. Elevated NSE levels are among the unfavourable prognostic factors

Open access

Yang Lv, Ning Pu, Wei-lin Mao, Wen-qi Chen, Huan-yu Wang, Xu Han, Yuan Ji, Lei Zhang, Da-yong Jin, Wen-Hui Lou, and Xue-feng Xu

primary cohort to identify related prognostic factors affecting overall survival (OS) of rectal NEC patients and to construct nomogram for prognosis prediction for these patients. Besides, the internal and external validations were also performed to

Open access

Keiko Ohkuwa, Kiminori Sugino, Mitsuji Nagahama, Wataru Kitagawa, Kenichi Matsuzu, Akifumi Suzuki, Chisato Tomoda, Kiyomi Hames, Junko Akaishi, Chie Masaki, and Koichi Ito

prognosis in patients with RAI-avid lung metastasis were found ( 16 , 17 ). This study aimed to determine the clinical prognostic factors, including NLR, in RAI-avid lung metastasis cases and to attempt risk classification to identify future cases for TKI

Open access

Andrea Mazurat, Andrea Torroni, Jane Hendrickson-Rebizant, Harbinder Benning, Richard W Nason, and K Alok Pathak

DSS were estimated by the Kaplan–Meier product limit method, and the effect of age and other prognostic factors on DSS was assessed using the log rank test for pairwise comparison. The competing influence of other causes of mortality, such as death due

Open access

Qi Zhang, Hongshan Wang, Yanhong Xie, Suming Huang, Ke Chen, Botian Ye, Yupeng Yang, Jie Sun, Hongyong He, Fenglin Liu, Zhenbin Shen, Weidong Chen, Kuntang Shen, Yuan Ji, and Yihong Sun

Kaplan–Meier curves, and comparisons were performed using log-rank test. Cox proportional hazards regression model was used to identify the prognostic factors. Statistical significance was defined as a two-sided P < 0.05. Results

Open access

Małgorzata Fuksiewicz, Maria Kowalska, Agnieszka Kolasińska-Ćwikła, Jarosław B Ćwikła, Łukasz Sawicki, Katarzyna Roszkowska-Purska, Joanna Drygiel, and Beata Kotowicz

, although in very small lesions, its level may be within the normal range ( 4 ). CgA in gastroenteropancreatic neuroendocrine neoplasms (GEP-NEN) can also serve as an independent prognostic factor for the evaluation of survival of patients. Previous studies

Open access

Malgorzata Oczko-Wojciechowska, Agnieszka Czarniecka, Tomasz Gawlik, Barbara Jarzab, and Jolanta Krajewska

that not only an absolute Ctn value but its dynamics is an even more important prognostic factor. According to published data, shorter Ctn doubling time, less than 6–24 months, negatively impacted recurrence-free and overall survival ( 1 , 3 , 7