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Impact of gender-affirming treatment on bone health in transgender and gender diverse youth

Silvia Ciancia

Silvia Ciancia Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium

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Vanessa Dubois

Vanessa Dubois Basic and Translational Endocrinology (BaTE), Department of Basic and Applied Medical Sciences, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium

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, and

Martine Cools

Martine Cools Department of Internal Medicine and Pediatrics, Ghent University, Pediatric Endocrinology Service, Ghent University Hospital, Ghent, Belgium

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estimate that 0.7% of Americans aged 13–24 years are transgender ( 3 ), and in many European countries, after the introduction of pediatric gender identity services, the yearly number of referrals has increased manifold in the last decade ( 4 , 5