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KORA Study Centre, University Hospital of Augsburg, Augsburg, Augsburg, Germany
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German Centre for Cardiovascular Research (DZHK), Partner site Munich Heart Alliance, Munich, Germany
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German Heart Centre Munich, Technical University of Munich, Munich, Germany
Institute of Epidemiology and Medical Biometry, University of Ulm, Ulm, Germany
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German Centre for Cardiovascular Research (DZHK), Partner Site Hamburg/Kiel/Lübeck, Hamburg, Germany
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similar chemical structures and physical properties, circulating at very different concentrations ( 6 , 7 ). More recently, measurements by liquid chromatography (LC) coupled to mass spectrometry (MS) became more widely available. It offers improved
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involved in the tryptophan metabolism by liquid chromatography−mass spectrometry (LC-MS). Methods Sample selection Patients were included from the Erasmus Medical Center NET database. The study was performed retrospectively, and, according to
Leeds Institute for Cardiovascular and Metabolic Medicine (LICAMM), University of Leeds, Leeds, UK
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Leeds Institute for Cardiovascular and Metabolic Medicine (LICAMM), University of Leeds, Leeds, UK
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were analysed by bioimpedance using a Tanita TBF 300MA monitor (Tanita, Manchester, UK). Regional fat mass was estimated using Harpenden skin callipers at the biceps, triceps, infrascapular, and suprailiac regions. A 12-lead electrocardiogram was
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estradiol in the used immunoassay. An alternative type of analysis to measure estradiol with no anticipated cross-reactivity to fulvestrant such as liquid chromatography-mass spectrometry could be used and has been recommended ( 15 ). However, it is not a