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Radiotherapy Related Research, The Christie NHS Foundation Trust, Manchester, UK
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efficacy and detrimental side effects, such as secondary neoplasms and endocrine deficiencies, is still needed. As the survival rate has also increased, patients are now living long enough to see these late effects. Common oncological treatments include
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Division of Cardiovascular and Diabetes Research, Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM), University of Leeds, Leeds, UK
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disease; however, an increase in cardiovascular mortality ( 5 ) and risk of early- and late-occurring stroke ( 6 , 7 ) are also observed. As a consequence, survivors are more likely to be hospitalised compared with the general population. Effects of
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2.2 CSOM230B2219 ( 9 ) 20 39 M N Y N Octreotide LAR + cabergoline 3.4 CSOM230B2219 ( 9 ) Bold indicates late responders (after ≥4 months of treatment). a Defined as baseline glucose ≥ 126 mg/dL, HbA1c ≥ 6
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inappropriately attributed to an individual who was not the first or even the most significant person involved in the description of the syndrome ( 2 ). A third reason is later appreciation of medically unethical behaviors of individuals with diseases eponymously
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Department of Rare Disorders and Disabilities, Oslo University Hospital, NevSom, Oslo, Norway
University of Oslo, Norwegian Centre for Mental Disorders Research (NORMENT) and KG Jebsen Centre for Neurodevelopmental Disorders, Oslo, Norway
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). Oxytocin functions both as a neurotransmitter and as a hormone. Intranasally administered oxytocin has been used to investigate the effects of oxytocin on social cognition and behavior in humans ( 21 ) as it increases oxytocin concentrations in the central
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Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK
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improvement on the 25-point QoL assessment scale (QoL-AGHDA) is demonstrated during the first 9 months of treatment. It remains uncertain, however, if the beneficial effects of GH administration are sustained throughout adult life. In fact, the few published
Department of Pediatric Endocrinology, Wilhelmina Children’s Hospital, University Medical Center, Lundlaan, EA Utrecht, The Netherlands
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Department of Pediatric Endocrinology, Wilhelmina Children’s Hospital, University Medical Center, Lundlaan, EA Utrecht, The Netherlands
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Department of Pediatric Endocrinology, Wilhelmina Children’s Hospital, University Medical Center, Lundlaan, EA Utrecht, The Netherlands
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mineral density surveillance for childhood, adolescent, and young adult cancer survivors: evidence-based recommendations from the International Late Effects of Childhood Cancer Guideline Harmonization Group . Lancet. Diabetes and Endocrinology 2021 9 622
Princess Máxima Center for Pediatric Oncology, AB Utrecht, The Netherlands
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the public, commercial or not-for-profit sector. References 1 Chemaitilly W Sklar CA . Childhood cancer treatments and associated endocrine late effects: a concise guide for the pediatric endocrinologist . Hormone Research in
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Department of Pediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus, Denmark
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Department of Pediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus, Denmark
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Department of Pediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus, Denmark
Steno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, Denmark
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physical chronic late effects ( 15 ) with growth hormone deficiency (GHD) being the most common endocrinopathy ( 16 ) followed by thyroid-stimulating hormone deficiency ( 17 ). CR is the most significant risk factor for the development of GHD ( 18
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Department of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands
Endo-ERN European Reference Network on Rare endocrine conditions
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Endo-ERN European Reference Network on Rare endocrine conditions
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Division of Endocrinology and Metabolism, Center for Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, Athens, Greece
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of the late effects of their brain tumor treatment until they occurred and therefore did not feel prepared for these late effects. According to the patients, some doctors focus too much on survival rather than on quality of life. Patients