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University Clinic of Medicine, Cantonal Hospital Baselland, Liestal, Switzerland
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of the observed magnitude and duration could have detrimental metabolic effects. So far, studies on meal-induced cortisol in obese subjects were scarce, and results were heterogeneous. In an observational study, obesity was associated with a poor
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medications have been created, none of the molecules is a complete treatment, and prolonged use of some of these synthetic drugs can have dangerous side effects ( 7 ). Using plants was reported to be a beneficial alternative therapy to manage and treat
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Department of Medicine, Copenhagen University Hospital – Amager and Hvidovre, Hvidovre, Denmark
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Imperial College Healthcare NHS Trust, St Mary’s Hospital, London, UK
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a day for people with flatulence (to attenuate side effects of acarbose) No comparator 85.8% reduction in episodes of early dumping and 95.7% reduction in episodes of late dumping (PBH) per week. Improvement in symptoms of early dumping as
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/L ( 10 ). Moreover, several studies have reported an association between hyperuricemia and adverse cardiovascular outcomes. Two of the main effects of hypertension, stroke and heart failure, have been linked to elevated SUA levels ( 11 , 12 , 13 ). A
Centre for Biological Timing, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK
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Diabetes, Endocrinology and Metabolism Centre, Manchester University NHS Foundation Trust, NIHR Manchester Biomedical Research Centre, Manchester Academic Health Science Centre, Manchester, UK
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Oxford Liver Unit, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, UK
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NIHR Oxford Health Biomedical Research Centre, and NIHR Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK
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NIHR Oxford Health Biomedical Research Centre, and NIHR Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK
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-shift workers. The way in which these relationships were attenuated on adjustment for BMI are in keeping with a mediating role of obesity, which was more prevalent in shift workers when compared to day workers. Furthermore, extreme late chronotype was also
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impaired glucose tolerance, T2DM, and gestational diabetes mellitus ( 19 ). We have recently reported rapid effects on neuroendocrine regulation following RYGB ( 8 ) as well as early and late adipose tissue effects in patients with obesity and T2DM ( 9
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Faculty of Medicine, University of Latvia, Riga, Latvia
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possibility is that the liver becomes tolerant to the hyperglycaemic effects of glucagon in T2D upon the use of long-acting glucagon agonists. Prolonged fasting also leads to a switch from glucagon to cortisol to maintain hepatic glucose production. In the
Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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Department of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark
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Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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effects of regular exercise training on insulin sensitivity, cardiorespiratory fitness, body composition, glycemic control, and lipid profile in patients with type 2 diabetes are well documented ( 3 , 4 ). Furthermore, there is evidence supporting a
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complete view regarding its relevant effects on growth and particularly do not allow to differentiate fast growers (bone age>calendar age) from late bloomers (bone age<calendar age). A strength of our study is the highly selected population of prepubertal
Leicester Diabetes Centre, University of Leicester, Leicester General Hospital, Leicester, UK
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Centre for Physical Activity in Health and Disease, Brunel University London, Uxbridge, UK
Division of Sport, Health and Exercise Sciences, Department of Life Sciences, Brunel University London, Uxbridge, UK
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-lunch period. In line with these findings, Holmstrup, Fairchild, Keslacy, Weinstock, Kanaley ( 10 ) found that the hunger-suppressing effects of moderate-intensity physical activity breaks compared to prolonged sitting occurred later in the day. This suggests