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then enter the blood vessel wall along with LDL molecules because of increased endothelial permeability. LDL is oxidized and taken up by the macrophages, which later become foam cells. This is followed by smooth cell proliferation and neovascularization
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previously in the SAGhE study, in adults without NS who were treated with GH during childhood ( 20 ). However, it was later shown that such concern was mainly driven by results from the French sub-cohort of SAGhE ( 21 ). Additionally, the investigating
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- and sex-matched control groups of patients with untreated AGHD for each year. Statistical analysis for this evaluation was planned and conducted to assess the mid-term and longer-term effects of GH therapy (Years 2 and 7, respectively). The results of
Sahlgrenska Osteoporosis Centre, Center for Bone and Arthritis Research (CBAR), Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden
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Sahlgrenska Osteoporosis Centre, Center for Bone and Arthritis Research (CBAR), Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden
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Sahlgrenska Osteoporosis Centre, Center for Bone and Arthritis Research (CBAR), Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden
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Department of Endocrinology, Skaraborg Central Hospital, Skövde, Sweden
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steroids exert effects on neuronal cells such as stimulating neurogenesis and brain plasticity, thereby modulating CNS functions ( 6 , 7 ). Furthermore, androgen and estrogen receptors, which mediate the effects of androgens (DHT and testosterone) and
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performed in studies involving human participants were in accordance with the Ethical Standards of the Institutional and/or National Research Committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. Informed