Clara Lundetoft Clausen
Clara Lundetoft Clausen
Center of Research & Disruption of Infectious Diseases, Department of Infectious Diseases, Copenhagen University Hospital - Amager and Hvidovre, Hvidovre, Denmark
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Trine Holm Johannsen
Trine Holm Johannsen
Department of Growth and Reproduction, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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Niels Erik Skakkebæk
Niels Erik Skakkebæk
Department of Growth and Reproduction, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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Hanne Frederiksen
Hanne Frederiksen
Department of Growth and Reproduction, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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Anders Juul
Anders Juul
Department of Growth and Reproduction, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Thomas Benfield
Thomas Benfield
Center of Research & Disruption of Infectious Diseases, Department of Infectious Diseases, Copenhagen University Hospital - Amager and Hvidovre, Hvidovre, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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important inhibitory effects towards pro-inflammatory mediators such as interleukin 6 (IL-6) ( 10 ). Therefore, in appropriate responses to critical illness and hyperinflammation, glucocorticoid levels are upregulated, attaining levels up to six
Martin Wiegand
Martin Wiegand
MRC Biostatistics Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK
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David J Halsall
David J Halsall
Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
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Sarah L Cowan
Sarah L Cowan
Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
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Kevin Taylor
Kevin Taylor
Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
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Robert J B Goudie
Robert J B Goudie
MRC Biostatistics Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK
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Jacobus Preller
Jacobus Preller
Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
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Mark Gurnell
Mark Gurnell
Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
Wellcome–MRC Institute of Metabolic Science, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Addenbrooke’s Hospital, Cambridge, UK
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Wellcome–MRC Institute of Metabolic Science, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Addenbrooke’s Hospital, Cambridge, UK
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supplementary materials given at the end of this article), although these patients had lower interleukin-6 (median 8.1 vs 11.9); were less likely to be admitted to ICU (11.2% vs 18.9%); and were more likely to have diabetes (32.8% vs 20.7%) or other endocrine
