Search Results

You are looking at 1 - 9 of 9 items for :

  • insulin-like growth factor-1 (IGF1) x
  • Paediatric Endocrinology x
Clear All
Alexandra Kiess Department of Pediatric Cardiology, Faculty of Medicine, Heart Center Leipzig, University of Leipzig, Strümpellstraße, Leipzig, Germany
Department of Child and Adolescent Medicine, Section of Pediatric Cardiology, University Hospital Jena, Am Klinikum, Jena, Germany

Search for other papers by Alexandra Kiess in
Google Scholar
PubMed
Close
,
Jessica Green Alder Hey Children's NHS Foundation Trust, Pediatric Intensive Care Unit, Eaton Road Liverpool, Great Britain

Search for other papers by Jessica Green in
Google Scholar
PubMed
Close
,
Anja Willenberg Institute of Laboratory Medicine, Clinical Chemistry, and Molecular Diagnostics (ILM), University of Leipzig, Liebigstrasse, Leipzig, Germany

Search for other papers by Anja Willenberg in
Google Scholar
PubMed
Close
,
Uta Ceglarek Institute of Laboratory Medicine, Clinical Chemistry, and Molecular Diagnostics (ILM), University of Leipzig, Liebigstrasse, Leipzig, Germany

Search for other papers by Uta Ceglarek in
Google Scholar
PubMed
Close
,
Ingo Dähnert Department of Pediatric Cardiology, Faculty of Medicine, Heart Center Leipzig, University of Leipzig, Strümpellstraße, Leipzig, Germany

Search for other papers by Ingo Dähnert in
Google Scholar
PubMed
Close
,
Wieland Kiess LIFE Leipzig Research Center for Civilization Diseases, University of Leipzig, Philipp-Rosenthal-Strasse, Leipzig, Germany
Department of Women and Child Health, Hospital for Children and Adolescents and Center for Pediatric Research (CPL), University of Leipzig, Liebigstrasse, Leipzig, Germany

Search for other papers by Wieland Kiess in
Google Scholar
PubMed
Close
, and
Mandy Vogel LIFE Leipzig Research Center for Civilization Diseases, University of Leipzig, Philipp-Rosenthal-Strasse, Leipzig, Germany
Department of Women and Child Health, Hospital for Children and Adolescents and Center for Pediatric Research (CPL), University of Leipzig, Liebigstrasse, Leipzig, Germany

Search for other papers by Mandy Vogel in
Google Scholar
PubMed
Close

Rychik J & Goldberg D . Usefulness of insulin like growth factor 1 as a marker of heart failure in children and young adults after the Fontan palliation procedure . American Journal of Cardiology 2015 15 816 – 820 . ( https://doi.org/10.1016/j

Open access
Lukas Plachy Department of Pediatrics, 2nd Faculty of Medicine, Charles University in Prague and University Hospital Motol, Prague, Czech Republic

Search for other papers by Lukas Plachy in
Google Scholar
PubMed
Close
,
Lenka Petruzelkova Department of Pediatrics, 2nd Faculty of Medicine, Charles University in Prague and University Hospital Motol, Prague, Czech Republic

Search for other papers by Lenka Petruzelkova in
Google Scholar
PubMed
Close
,
Petra Dusatkova Department of Pediatrics, 2nd Faculty of Medicine, Charles University in Prague and University Hospital Motol, Prague, Czech Republic

Search for other papers by Petra Dusatkova in
Google Scholar
PubMed
Close
,
Klara Maratova Department of Pediatrics, 2nd Faculty of Medicine, Charles University in Prague and University Hospital Motol, Prague, Czech Republic

Search for other papers by Klara Maratova in
Google Scholar
PubMed
Close
,
Dana Zemkova Department of Pediatrics, 2nd Faculty of Medicine, Charles University in Prague and University Hospital Motol, Prague, Czech Republic

Search for other papers by Dana Zemkova in
Google Scholar
PubMed
Close
,
Lenka Elblova Department of Pediatrics, 2nd Faculty of Medicine, Charles University in Prague and University Hospital Motol, Prague, Czech Republic

Search for other papers by Lenka Elblova in
Google Scholar
PubMed
Close
,
Vit Neuman Department of Pediatrics, 2nd Faculty of Medicine, Charles University in Prague and University Hospital Motol, Prague, Czech Republic

Search for other papers by Vit Neuman in
Google Scholar
PubMed
Close
,
Stanislava Kolouskova Department of Pediatrics, 2nd Faculty of Medicine, Charles University in Prague and University Hospital Motol, Prague, Czech Republic

Search for other papers by Stanislava Kolouskova in
Google Scholar
PubMed
Close
,
Barbora Obermannova Department of Pediatrics, 2nd Faculty of Medicine, Charles University in Prague and University Hospital Motol, Prague, Czech Republic

Search for other papers by Barbora Obermannova in
Google Scholar
PubMed
Close
,
Marta Snajderova Department of Pediatrics, 2nd Faculty of Medicine, Charles University in Prague and University Hospital Motol, Prague, Czech Republic

Search for other papers by Marta Snajderova in
Google Scholar
PubMed
Close
,
Zdenek Sumnik Department of Pediatrics, 2nd Faculty of Medicine, Charles University in Prague and University Hospital Motol, Prague, Czech Republic

Search for other papers by Zdenek Sumnik in
Google Scholar
PubMed
Close
,
Jan Lebl Department of Pediatrics, 2nd Faculty of Medicine, Charles University in Prague and University Hospital Motol, Prague, Czech Republic

Search for other papers by Jan Lebl in
Google Scholar
PubMed
Close
, and
Stepanka Pruhova Department of Pediatrics, 2nd Faculty of Medicine, Charles University in Prague and University Hospital Motol, Prague, Czech Republic

Search for other papers by Stepanka Pruhova in
Google Scholar
PubMed
Close

transmitted mainly in an autosomal dominant (AD) matter and may thus cause monogenic FSS. Apart from growth plate disorders, heterozygous mutations in genes affecting the growth hormone (GH)–insulin-like growth factor (IGF) axis are also known to cause

Open access
Alberto Battezzati International Center for the Assessment of Nutritional Status, DeFENS, University of Milan, Milan, Italy

Search for other papers by Alberto Battezzati in
Google Scholar
PubMed
Close
,
Andrea Foppiani International Center for the Assessment of Nutritional Status, DeFENS, University of Milan, Milan, Italy

Search for other papers by Andrea Foppiani in
Google Scholar
PubMed
Close
,
Gianfranco Alicandro Cystic Fibrosis Center, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ca’ Granda, Ospedale Maggiore Policlinico, University of Milan, Milan, Italy

Search for other papers by Gianfranco Alicandro in
Google Scholar
PubMed
Close
,
Arianna Bisogno Cystic Fibrosis Center, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ca’ Granda, Ospedale Maggiore Policlinico, University of Milan, Milan, Italy

Search for other papers by Arianna Bisogno in
Google Scholar
PubMed
Close
,
Arianna Biffi Cystic Fibrosis Center, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ca’ Granda, Ospedale Maggiore Policlinico, University of Milan, Milan, Italy

Search for other papers by Arianna Biffi in
Google Scholar
PubMed
Close
,
Giorgio Bedogni Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy
Internal Medicine, S. Maria delle Croci Hospital, AUSL Romagna, Ravenna, Italy

Search for other papers by Giorgio Bedogni in
Google Scholar
PubMed
Close
,
Simona Bertoli International Center for the Assessment of Nutritional Status, DeFENS, University of Milan, Milan, Italy
Istituto Auxologico Italiano, IRCCS, Obesity Unit - Laboratory of Nutrition and Obesity Research, Department of Endocrine and Metabolic Diseases, Milan, Italy

Search for other papers by Simona Bertoli in
Google Scholar
PubMed
Close
,
Giulia De Carlo International Center for the Assessment of Nutritional Status, DeFENS, University of Milan, Milan, Italy

Search for other papers by Giulia De Carlo in
Google Scholar
PubMed
Close
,
Erica Nazzari Cystic Fibrosis Center, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ca’ Granda, Ospedale Maggiore Policlinico, University of Milan, Milan, Italy

Search for other papers by Erica Nazzari in
Google Scholar
PubMed
Close
, and
Carla Colombo Cystic Fibrosis Center, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ca’ Granda, Ospedale Maggiore Policlinico, University of Milan, Milan, Italy

Search for other papers by Carla Colombo in
Google Scholar
PubMed
Close

studies in type 1 diabetes and in healthy subjects. According to mechanistic studies, insulin is one of the main regulators of growth hormone (GH)/insulin-like growth factor 1 (IGF-1) axis ( 21 ), frequently involved in growth failure associated with

Open access
Alexander A L Jorge Unidade de Endocrinologia-Genetica, LIM/25, Disciplina de Endocrinologia da Faculdade de Medicina da Universidade de Sao Paulo (FMUSP), Sao Paulo, Brazil

Search for other papers by Alexander A L Jorge in
Google Scholar
PubMed
Close
,
Thomas Edouard Endocrine, Bone Diseases, and Genetics Unit, Children’s Hospital, Toulouse University Hospital, RESTORE INSERM UMR1301, Toulouse, France

Search for other papers by Thomas Edouard in
Google Scholar
PubMed
Close
,
Mohamad Maghnie Department of Pediatrics, IRCCS Istituto Giannina Gaslini, Genova, Italy
Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy

Search for other papers by Mohamad Maghnie in
Google Scholar
PubMed
Close
,
Alberto Pietropoli Novo Nordisk Health Care AG, Global Medical Affairs Biopharm, Zürich, Switzerland

Search for other papers by Alberto Pietropoli in
Google Scholar
PubMed
Close
,
Nicky Kelepouris Novo Nordisk Inc., Clinical, Medical and Regulatory Biopharm-RED, Plainsboro, New Jersey, USA

Search for other papers by Nicky Kelepouris in
Google Scholar
PubMed
Close
,
Alicia Romano Department of Pediatrics, New York Medical College, Valhalla, New York, USA

Search for other papers by Alicia Romano in
Google Scholar
PubMed
Close
,
Martin Zenker Institute of Human Genetics & Department of Pediatrics, University Hospital, Otto-von-Guericke University Magdeburg, Magdeburg, Germany

Search for other papers by Martin Zenker in
Google Scholar
PubMed
Close
, and
Reiko Horikawa Department of Endocrine and Metabolism, National Center for Child Health and Development, Tokyo, Japan

Search for other papers by Reiko Horikawa in
Google Scholar
PubMed
Close

.9 (0.3) 20 0.8 (0.2) IGF-I SDS, mean ( s.d. ) 35 −1.5 (1.3) 20 −1.2 (0.8) n, number of patients with available data. GH, growth hormone; IGF-I, insulin-like growth factor I; NS, Noonan syndrome; SDS, standard deviation

Open access
Martin Bidlingmaier Medizinische Klinik und Poliklinik IV, LMU Klinikum, Ludwig-Maximilians University, Munich, Germany

Search for other papers by Martin Bidlingmaier in
Google Scholar
PubMed
Close
,
Helena Gleeson Department of Endocrinology, Queen Elizabeth Hospital, Birmingham, UK

Search for other papers by Helena Gleeson in
Google Scholar
PubMed
Close
,
Ana-Claudia Latronico Department of Internal Medicine, Discipline of Endocrinology and Metabolism, Sao Paulo Medical School, University of Sao Paulo, Sao Paulo, Brazil

Search for other papers by Ana-Claudia Latronico in
Google Scholar
PubMed
Close
, and
Martin O Savage Centre for Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, London, UK

Search for other papers by Martin O Savage in
Google Scholar
PubMed
Close

GnRH CPP, central precocious puberty; DDX3X, DEAD-box helicase 3; DLK1, delta-like 1 homologue; GnRH, gonadotropin hormone-releasing hormone; IG-DMR, intergenic differentially methylated regions; IGF2, insulin-like growth factor 2; KMT2D

Open access
Patrizia Bruzzi Department of Medical and Surgical Sciences of Mothers, Children and Adults, University of Modena & Reggio Emilia, Paediatric Unit, Modena, Italy

Search for other papers by Patrizia Bruzzi in
Google Scholar
PubMed
Close
,
Silvia Vannelli Pediatric Endocrinologic Unit, Regina Margherita Children’s Hospital, Turin, Italy

Search for other papers by Silvia Vannelli in
Google Scholar
PubMed
Close
,
Emanuela Scarano Unit of Pediatrics, Department of Medical and Surgical Sciences, Policlinico St. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy

Search for other papers by Emanuela Scarano in
Google Scholar
PubMed
Close
,
Natascia Di Iorgi Department of Pediatrics, IRCCS Istituto Giannina Gaslini, University of Genova, Genova, Italy

Search for other papers by Natascia Di Iorgi in
Google Scholar
PubMed
Close
,
Maria Parpagnoli Anna Meyer Children's University Hospital, Florence, Italy

Search for other papers by Maria Parpagnoli in
Google Scholar
PubMed
Close
,
MariaCarolina Salerno Department of Translational Medicine, University Federico II, Naples, Italy

Search for other papers by MariaCarolina Salerno in
Google Scholar
PubMed
Close
,
Marco Pitea Pediatric Unit, Ospedale San Raffaele, Milano, Italy

Search for other papers by Marco Pitea in
Google Scholar
PubMed
Close
,
Maria Elisabeth Street Division of Paediatric Endocrinology and Diabetology, Paediatrics, Department of Mother and Child-AUSL of Reggio Emilia-IRCCS, Reggio Emilia, Italy

Search for other papers by Maria Elisabeth Street in
Google Scholar
PubMed
Close
,
Andrea Secco Pediatric Unit, Azienda ospedaliero Nazionale SS Antonio e Biagio e Cesare Arrigo, Alessandria, Italy

Search for other papers by Andrea Secco in
Google Scholar
PubMed
Close
,
Adolfo Andrea Trettene Pediatric Unit, ASST Sette Laghi, Varese, Italy

Search for other papers by Adolfo Andrea Trettene in
Google Scholar
PubMed
Close
,
Malgorzata Wasniewska Department of Human Pathology in Adulthood and Childhood, University of Messina, Messina, Italy

Search for other papers by Malgorzata Wasniewska in
Google Scholar
PubMed
Close
,
Nicola Corciulo Pediatric Unit, P.O. Gallipoli, ASL Lecce, Italy

Search for other papers by Nicola Corciulo in
Google Scholar
PubMed
Close
,
Gianluca Tornese Institute for maternal and child health IRCCS Burlo Garofalo, Trieste, Italy

Search for other papers by Gianluca Tornese in
Google Scholar
PubMed
Close
,
Maria Felicia Faienza DAI Scienze Chirurgiche e Pediatriche, Ospedale Pediatrico Giovanni XXIII, Bari, Italy

Search for other papers by Maria Felicia Faienza in
Google Scholar
PubMed
Close
,
Maurizio Delvecchio U.O. Malattie Metaboliche e Genetiche e Diabetologia, Ospedale Pediatrico Giovanni XXIII, Bari, Italy

Search for other papers by Maurizio Delvecchio in
Google Scholar
PubMed
Close
,
Simona Filomena Madeo Department of Medical and Surgical Sciences of Mothers, Children and Adults, University of Modena & Reggio Emilia, Paediatric Unit, Modena, Italy

Search for other papers by Simona Filomena Madeo in
Google Scholar
PubMed
Close
, and
Lorenzo Iughetti Department of Medical and Surgical Sciences of Mothers, Children and Adults, University of Modena & Reggio Emilia, Paediatric Unit, Modena, Italy

Search for other papers by Lorenzo Iughetti in
Google Scholar
PubMed
Close

verified and collected at each study time. All patients were submitted to rhGH treatment according to the Italian Agency for Drugs guidelines ( 25 ). Biochemical analysis Fasting glucose, insulin and insulin-like growth factor 1 (IGF1) values were

Open access
Danielle Christine Maria van der Kaay Erasmus University Medical Center, Department of Pediatrics, Subdivision of Endocrinology, Rotterdam, Netherlands

Search for other papers by Danielle Christine Maria van der Kaay in
Google Scholar
PubMed
Close
,
Anne Rochtus Department of Pediatric Endocrinology, University Hospitals Leuven, Leuven, Belgium

Search for other papers by Anne Rochtus in
Google Scholar
PubMed
Close
,
Gerhard Binder University Children’s Hospital, Pediatric Endocrinology, University of Tübingen, Tübingen, Germany

Search for other papers by Gerhard Binder in
Google Scholar
PubMed
Close
,
Ingo Kurth Institute of Human Genetics, Medical Faculty, RWTH Aachen University, Aachen, Germany

Search for other papers by Ingo Kurth in
Google Scholar
PubMed
Close
,
Dirk Prawitt Center for Paediatrics and Adolescent Medicine, University Medical Center, Mainz, Germany

Search for other papers by Dirk Prawitt in
Google Scholar
PubMed
Close
,
Irène Netchine Sorbonne Université, Centre de Recherche Saint-Antoine, INSERM, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France

Search for other papers by Irène Netchine in
Google Scholar
PubMed
Close
,
Gudmundur Johannsson Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
Department of Endocrinology at Sahlgrenska University Hospital, Gothenburg, Sweden

Search for other papers by Gudmundur Johannsson in
Google Scholar
PubMed
Close
,
Anita C S Hokken-Koelega Erasmus University Medical Center, Department of Pediatrics, Subdivision of Endocrinology, Rotterdam, Netherlands

Search for other papers by Anita C S Hokken-Koelega in
Google Scholar
PubMed
Close
,
Miriam Elbracht Institute of Human Genetics, Medical Faculty, RWTH Aachen University, Aachen, Germany

Search for other papers by Miriam Elbracht in
Google Scholar
PubMed
Close
, and
Thomas Eggermann Institute of Human Genetics, Medical Faculty, RWTH Aachen University, Aachen, Germany

Search for other papers by Thomas Eggermann in
Google Scholar
PubMed
Close

radiologic and clinical examinations suggest an endocrine cause of the growth disturbance, growth hormone stimulation tests (GHSTs), serum insulin-like growth factor (IGF1), and sometimes an IGF1 generation test are used to investigate the growth hormone (GH)–IGF

Open access
Rebeca Esquivel-Zuniga Department of Pediatrics, University of Virginia, Charlottesville, Virginia, USA

Search for other papers by Rebeca Esquivel-Zuniga in
Google Scholar
PubMed
Close
and
Alan D Rogol Department of Pediatrics, University of Virginia, Charlottesville, Virginia, USA

Search for other papers by Alan D Rogol in
Google Scholar
PubMed
Close

, growth hormone; GI, gastrointestinal; GnRH, gonadotropin-releasing hormone; hCG, human chorionic gonadotropin; IGF-1, insulin-like growth factor 1; LH, luteinizing hormone; MRI, magnetic resonance imaging ( 3 ). From New England Journal of Medicine

Open access
Christine Poitou Assistance Publique-Hôpitaux de Paris, Centre de référence Maladies Rares (PRADORT, Syndrome de Prader-Willi et autres formes rares d’obésité avec troubles du comportement alimentaire), Service de Nutrition, Hôpital Pitié-Salpêtrière, Paris, France

Search for other papers by Christine Poitou in
Google Scholar
PubMed
Close
,
Anthony Holland Department of Psychiatry, University of Cambridge, UK

Search for other papers by Anthony Holland in
Google Scholar
PubMed
Close
,
Charlotte Höybye Department of Endocrinology and Department of Molecular Medicine and Surgery, Karolinska University Hospital and Karolinska Institute, Stockholm, Sweden

Search for other papers by Charlotte Höybye in
Google Scholar
PubMed
Close
,
Laura C G de Graaff Center for Adults with Rare Genetic Syndromes, Department of Internal Medicine, Division of Endocrinology, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, The Netherlands

Search for other papers by Laura C G de Graaff in
Google Scholar
PubMed
Close
,
Sandrine Bottius Assistance Publique-Hôpitaux de Paris, Centre de référence Maladies Rares (PRADORT, Syndrome de Prader-Willi et autres formes rares d’obésité avec troubles du comportement alimentaire), Service de Nutrition, Hôpital Pitié-Salpêtrière, Paris, France

Search for other papers by Sandrine Bottius in
Google Scholar
PubMed
Close
,
Berit Otterlei Landsforeningen for Prader-Willis Syndrom Hiltonåsen, Slependen, Norway

Search for other papers by Berit Otterlei in
Google Scholar
PubMed
Close
, and
Maithé Tauber Centre de référence Maladies Rares (PRADORT, Syndrome de Prader-Willi et autres formes rares d’obésité avec troubles du comportement alimentaire), Service d’Endocrinologie, Obésités, Maladies Osseuses, Génétique et Gynécologie Médicale, Hôpital des Enfants, Toulouse, France

Search for other papers by Maithé Tauber in
Google Scholar
PubMed
Close

origin and most GH stimulation tests stimulate the secretion of GH from the pituitary gland which may result in falsely normal GH responses ( 2 , 16 ). The marker of GH activity insulin-like growth factor I (IGF-I) is below normal in 75–91% ( 2 , 16

Open access