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Royal Marsden Hospital, London, UK
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predominately on symptom severity at presentation is not helpful in guiding decisions about hormone replacement and continuation or discontinuation of ICPI therapy for endocrinopathies ( 2 ). Immune-related endocrinopathies do not fit into a five-tier symptoms
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Universidad La Salle, Posgrado de la Facultad de Ciencias Químicas, Ciudad de México, México
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in tumor cell proliferation after E2 treatment ( 28 ). Moreover, hormone replacement therapy in menopausal women is recognized as a risk factor for ovarian cancer ( 29 ); consequently, tumor progression associated with the presence of E2 might be
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demonstrated longer survival for panNET-G3 (range, 41–42 months) than for panNEC (range, 9–17 months) ( 8 , 9 ). Moreover, it has been hypothesized that panNET-G3 and panNEC respond differently to systemic therapy, with higher response rates on platinum
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/6 inhibitors and also in monotherapy. In premenopausal patients, fulvestrant requires the combination with a gonadotropin‐releasing hormone (GnRH) agonist therapy for ovarian suppression (OS) ( 6 ). However, studies show that 17–24% ( 7 , 8 ) of
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Department of Florey Institute, University of Melbourne, Parkville, Victoria, Australia
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Introduction Androgen deprivation therapy (ADT) using gonadotropin-releasing hormone (GnRH) agonists is one of the mainstay therapies for prostate cancer ( 1 ). This therapy reduces circulating testosterone to castrate concentrations
Department of Public Health, Erasmus University Medical Center, Rotterdam, Netherlands
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Department of Endocrinology and Metabolism, Amsterdam Gastroenterology Endocrinology Metabolism (AGEM), Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands
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Department of Endocrinology and Metabolism, Amsterdam Gastroenterology Endocrinology Metabolism (AGEM), Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands
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Netherlands Comprehensive Cancer Organisation, Utrecht, Netherlands
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Department of Epidemiology and Data Science, Amsterdam UMC, Amsterdam, Netherlands
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.nivel.nl/nl/nivel-zorgregistraties-eerste-lijn/jaarcijfers-aandoeningen-incidenties-en-prevalenties ). Treatment of primary hypothyroidism consists of hormone substitution therapy with daily oral administration of the synthetic thyroid hormone levothyroxine. The majority of levothyroxine is absorbed in the upper gastrointestinal tract, ranging from 40 to 80
Department of Oncology, Comprehensive Cancer Centre, Helsinki University Hospital, Helsinki, Finland
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Department of Oncology, Comprehensive Cancer Centre, Helsinki University Hospital, Helsinki, Finland
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Department of Radiology, HUS Medical Imaging Centre, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
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Department of Radiology, HUS Medical Imaging Centre, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
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Endocrinology, Abdominal Centre, University of Helsinki and HUS, Helsinki, Finland
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Department of Oncology, Comprehensive Cancer Centre, Helsinki University Hospital, Helsinki, Finland
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permanent hormone deficiencies requiring lifelong substitution therapies, but on the other hand, endocrine AEs seem to be related to longer PFS and OS. Based on our results, a systematic laboratory and patient follow-up are highly recommendable during ICI
European Institute for Molecular Imaging (EIMI), University of Münster, Münster, Germany
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time of diagnosis ( 1 ) which generally requires a systemic therapy in addition to surgery and/or radiation therapy. A recent single-institution retrospective study on 479 patients treated at the University of Texas MD Anderson Cancer Center over 20
Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
Garvan Institute of Medical Research, New South Wales, Australia
School of Medical Sciences, University of New South Wales, New South Wales, Australia
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Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
Department of Diabetes and Endocrinology, Westmead Hospital, New South Wales, Australia
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Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
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Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
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Faculty of Medicine, Health and Human Sciences, Macquarie University, New South Wales, Australia
Crown Princess Mary Cancer Centre, Westmead Hospital, New South Wales, Australia
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Endocrine Research Unit, Department of Endocrinology, Odense University Hospital & Department of Clinical Research, Faculty of Health, University of Southern Denmark, Odense, Denmark
Steno Diabetes Center Odense, Odense University Hospital & Department of Clinical Research, Faculty of Health, University of Southern Denmark, Odense, Denmark
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Endocrine Research Unit, Department of Endocrinology, Odense University Hospital & Department of Clinical Research, Faculty of Health, University of Southern Denmark, Odense, Denmark
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radiation therapy for high-risk prostate cancer. Exclusion criteria were visceral metastases, castrate-resistant prostate cancer (PSA progression defined as at least 3 PSA rises, measured on three successive occasions ≥ 1 week apart after hormonal
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triiodothyronine, thyroxine, free triiodothyronine (FT3), free thyroxine (FT4), ultrasensitive thyroid-stimulating hormone (uTSH), thyroid peroxidase antibody (TPOAb), thyroid antithyroglobulin autoantibody (TgAb) and parathyroid hormone were detected by an