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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark
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Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark
Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Introduction Prednisolone, a corticosteroid-based drug, is used in a wide range of diseases due to its anti-inflammatory and immunosuppressant effects ( 1 , 2 , 3 , 4 ). Glucocorticoids affect various human tissues, and it has been shown
Centre for Biological Timing, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK
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Diabetes, Endocrinology and Metabolism Centre, Manchester University NHS Foundation Trust, NIHR Manchester Biomedical Research Centre, Manchester Academic Health Science Centre, Manchester, UK
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Oxford Liver Unit, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, UK
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NIHR Oxford Health Biomedical Research Centre, and NIHR Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK
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NIHR Oxford Health Biomedical Research Centre, and NIHR Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK
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therapeutic glucocorticoids show differential effects depending on circadian phase, due to circadian modulation of glucocorticoid receptor cistromes ( 22 ). Conclusion This study shows that shift workers have a higher likelihood of developing
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diabeticorum is multimodal consisting of emollients, topical glucocorticoids and immunomodulators and systemic antihistamines, for example. Also, mild skin care with synthetic detergents rather than alkalic soaps and the avoidance of potential contact allergens
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the proportion of glucose data captured ≥75%. Exclusion criteria included: (i) fasting C peptide > 200 pmol/L; (ii) receiving glucocorticoid treatment; (iii) pregnancy or lactation and (iv) history of severe cardiovascular diseases, cerebrovascular
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(i) secondary obesity, including Cushing’s syndrome, polycystic ovary syndrome (PCOS) and uncontrolled hypothyroidism; (ii) use of anti-diabetic, slimming drugs, glucocorticoids, antidepressant or antianxiety medications; (iii) pregnancy or lactation
Comprehensive Heart Failure Center, University & University Hospital Würzburg, Würzburg, Germany
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Department of Psychiatry, Psychosomatics and Psychotherapy, University Hospital, University of Würzburg, Würzburg, Germany
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Division of Cardiology, Department of Internal Medicine I, University Hospital, University of Würzburg, Würzburg, Germany
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Department of General, Visceral, Transplant, Vascular, and Pediatric Surgery, University Hospital, University of Würzburg, Würzburg, Germany
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Division of Cardiology, Department of Internal Medicine I, University Hospital, University of Würzburg, Würzburg, Germany
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Division of Cardiology, Department of Internal Medicine I, University Hospital, University of Würzburg, Würzburg, Germany
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Comprehensive Heart Failure Center, University & University Hospital Würzburg, Würzburg, Germany
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• Unstable angina pectoris • Life expectancy <12 months • Endocrine or psychiatric disorder as cause of obesity • Systemic glucocorticoid treatment (with exception of glucocorticoid replacement therapy) • Abuse of drugs or alcohol within the last 5 years
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), missing thyroid parameters ( n = 4), had a history of thyroid surgery or known thyroid dysfunction,that is, all potential users of drugs for thyroid dysfunction ( n = 274), had a history of glucocorticoid or amiodarone treatment ( n = 177), had an
Clinical Research Center for Metabolic Disease, Gansu Province, Lanzhou, Gansu, China
The First School of Clinical Medicine, Lanzhou University, Lanzhou, Gansu, China
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The First School of Clinical Medicine, Lanzhou University, Lanzhou, Gansu, China
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The First School of Clinical Medicine, Lanzhou University, Lanzhou, Gansu, China
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The First School of Clinical Medicine, Lanzhou University, Lanzhou, Gansu, China
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Clinical Research Center for Metabolic Disease, Gansu Province, Lanzhou, Gansu, China
The First School of Clinical Medicine, Lanzhou University, Lanzhou, Gansu, China
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exclusion criteria were as follows: use of drugs that interfered with blood glucose levels, such as glucocorticoids, metformin, and glibenclamide; use of hypolipidemic drugs within six months; current or previous history of severe hepatic disease, cancer
Department of Endocrinology, Austin Health, Melbourne, Australia
Division of Endocrinology, Diabetes and Metabolism, Northwell, Great Neck, New York, USA
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Department of Cardiology, Austin Health, Melbourne Australia
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Olivia Newton-John Cancer Research Institute, Austin Health, Melbourne, Australia
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Department of Endocrinology, Austin Health, Melbourne, Australia
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Department of Endocrinology, Austin Health, Melbourne, Australia
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, exposure to hormone replacement therapy within the 3 months prior to study screening, exposure to glucocorticoid use for ≥2 weeks continuously within the 3 months prior to screening or preexisting diabetes (requiring glucose-lowering medication