Sophie Howarth
Sophie Howarth
Clinical and Translational Research Institute, Newcastle University, Newcastle upon Tyne, UK
Department of Endocrinology, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK
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Department of Endocrinology, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK
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Luca Giovanelli
Luca Giovanelli
Department of Endocrinology, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK
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Catherine Napier
Catherine Napier
Department of Endocrinology, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK
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Simon H Pearce
Simon H Pearce
Clinical and Translational Research Institute, Newcastle University, Newcastle upon Tyne, UK
Department of Endocrinology, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK
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Department of Endocrinology, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK
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loss, hypoglycaemia and fatigue. Historically, the symptomatic phase was felt to be a point of no return for Addison’s patients, with a lifelong requirement for steroid replacement to avoid fatal adrenal crisis. However, a growing body of evidence
Gemma White
Gemma White
Department of Diabetes and Endocrinology, Guy’s and St Thomas’ NHS Foundation Trust, London, UK
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Anand Velusamy
Anand Velusamy
Department of Diabetes and Endocrinology, Guy’s and St Thomas’ NHS Foundation Trust, London, UK
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Samantha Anandappa
Samantha Anandappa
Department of Diabetes and Endocrinology, Guy’s and St Thomas’ NHS Foundation Trust, London, UK
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Michael Masucci
Michael Masucci
Department of Diabetes and Endocrinology, Guy’s and St Thomas’ NHS Foundation Trust, London, UK
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Louise A Breen
Louise A Breen
Department of Diabetes and Endocrinology, Guy’s and St Thomas’ NHS Foundation Trust, London, UK
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Mamta Joshi
Mamta Joshi
Department of Diabetes and Endocrinology, Guy’s and St Thomas’ NHS Foundation Trust, London, UK
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Barbara McGowan
Barbara McGowan
Department of Diabetes and Endocrinology, Guy’s and St Thomas’ NHS Foundation Trust, London, UK
Faculty of Life Sciences and Medicine, King’s College London, London, UK
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Faculty of Life Sciences and Medicine, King’s College London, London, UK
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Johnathan G H Hubbard
Johnathan G H Hubbard
Department of Endocrine Surgery, Guy’s and St Thomas’ NHS Foundation Trust, London, UK
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Rupert Obholzer
Rupert Obholzer
Department of Ear, Nose and Throat Surgery, Guy’s and St Thomas’ NHS Foundation Trust, London, UK
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Dimitra Christodoulou
Dimitra Christodoulou
Department of Radiology, Guy’s and St Thomas’ NHS Foundation Trust, London, UK
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Audrey Jacques
Audrey Jacques
Department of Radiology, Guy’s and St Thomas’ NHS Foundation Trust, London, UK
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Philip Touska
Philip Touska
Department of Radiology, Guy’s and St Thomas’ NHS Foundation Trust, London, UK
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Fahim-Ul Hassan
Fahim-Ul Hassan
Department of Nuclear Medicine, Guy’s and St Thomas’ NHS Foundation Trust, London, UK
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Louise Izatt
Louise Izatt
Department of Clinical Genetics, Guy’s and St Thomas’ NHS Foundation Trust, London, UK
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Paul V Carroll
Paul V Carroll
Department of Diabetes and Endocrinology, Guy’s and St Thomas’ NHS Foundation Trust, London, UK
Faculty of Life Sciences and Medicine, King’s College London, London, UK
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Faculty of Life Sciences and Medicine, King’s College London, London, UK
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growing evidence base to advocate genetic screening in all PPGL cases ( 10 ). In solitary low-risk PCC in the absence of family history, genetic testing is currently funded by NHS England when diagnosed in patients under 60 years of age or if
Angelica Sharma
Angelica Sharma
Division of Diabetes, Endocrinology and Metabolism, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK
Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Katharine Lazarus
Katharine Lazarus
Division of Diabetes, Endocrinology and Metabolism, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK
Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Deborah Papadopoulou
Deborah Papadopoulou
Division of Diabetes, Endocrinology and Metabolism, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK
Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Hemanth Prabhudev
Hemanth Prabhudev
Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Tricia Tan
Tricia Tan
Division of Diabetes, Endocrinology and Metabolism, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK
Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
Department of Clinical Biochemistry, North West London Pathology, London, UK
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Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
Department of Clinical Biochemistry, North West London Pathology, London, UK
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Karim Meeran
Karim Meeran
Division of Diabetes, Endocrinology and Metabolism, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK
Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Sirazum Choudhury
Sirazum Choudhury
Division of Diabetes, Endocrinology and Metabolism, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK
Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
Department of Clinical Biochemistry, North West London Pathology, London, UK
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Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
Department of Clinical Biochemistry, North West London Pathology, London, UK
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adverse metabolic outcomes associated with prednisolone are based on evidence using higher doses of prednisolone. A study analysing 25 patients receiving either hydrocortisone (30 mg/day) or prednisolone (7.5 mg/day) concluded that a greater proportion of
Sriharsha Gunna
Sriharsha Gunna
Department of Endocrinology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
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Mahaveer Singh
Mahaveer Singh
Department of Endocrinology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
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Rakesh Pandey
Rakesh Pandey
Department of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
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Rungmei S K Marak
Rungmei S K Marak
Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
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Amita Aggarwal
Amita Aggarwal
Department of Clinical Immunology and Rheumatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
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Bibhuti Mohanta
Bibhuti Mohanta
Department of Endocrinology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
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Liping Yu
Liping Yu
Barbara Davis Centre for Diabetes, School of Medicine University of Colorado, Aurora, Colorado, USA
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Eesh Bhatia
Eesh Bhatia
Department of Endocrinology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
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infusion ( 2 ). Evidence of infection with tuberculosis (current or past history of extra-AT and prescription of treatment with anti-tuberculous drugs) or Histoplasma (history of exposure to birds, cave exploration and farming occupation) was sought
Victor Jing-Wei Kang
Victor Jing-Wei Kang
Departments of Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan
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Bo-Ching Lee
Bo-Ching Lee
Departments of Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan
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Jia-Zheng Huang
Jia-Zheng Huang
Departments of Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan
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Vin-Cent Wu
Vin-Cent Wu
Departments of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
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Yen-Hung Lin
Yen-Hung Lin
Departments of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
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Chin-Chen Chang
Chin-Chen Chang
Departments of Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan
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TAIPAI group
TAIPAI group
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evidence of adenoma after adrenalectomy and subsequent clinical improvement defined as either complete resolution of hypertension or partial resolution of hypertension, potassium, PAC, and PRA ( 18 ). Imaging analysis Adrenal CT images were
Ramjan Sanas Mohamed
Ramjan Sanas Mohamed
Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Biyaser Abuelgasim
Biyaser Abuelgasim
Imperial College School of Medicine, Department of Biochemistry, Imperial College Healthcare NHS Trust, London, UK
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Sally Barker
Sally Barker
Imperial College School of Medicine, Department of Biochemistry, Imperial College Healthcare NHS Trust, London, UK
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Hemanth Prabhudev
Hemanth Prabhudev
Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Niamh M Martin
Niamh M Martin
Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
Division of Diabetes, Endocrinology and Metabolism, Imperial College London, London, UK
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Division of Diabetes, Endocrinology and Metabolism, Imperial College London, London, UK
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Karim Meeran
Karim Meeran
Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
Division of Diabetes, Endocrinology and Metabolism, Imperial College London, London, UK
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Division of Diabetes, Endocrinology and Metabolism, Imperial College London, London, UK
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Emma L Williams
Emma L Williams
Department of Biochemistry, Imperial College Healthcare NHS Trust, London, UK
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Sarah Darch
Sarah Darch
Department of Biochemistry, Imperial College Healthcare NHS Trust, London, UK
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Whitlock Matthew
Whitlock Matthew
Department of Biochemistry, Imperial College Healthcare NHS Trust, London, UK
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Tricia Tan
Tricia Tan
Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
Division of Diabetes, Endocrinology and Metabolism, Imperial College London, London, UK
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Division of Diabetes, Endocrinology and Metabolism, Imperial College London, London, UK
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Florian Wernig
Florian Wernig
Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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. Salivary cortisone can be reliably measured by liquid chromatography-tandem mass spectrometry (LC-MS/MS) ( 7 ). There is no evidence of 11B-HSD2 activity in collected saliva. Therefore, measurement of salivary cortisone is particularly useful when
Martin Wiegand
Martin Wiegand
MRC Biostatistics Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK
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David J Halsall
David J Halsall
Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
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Sarah L Cowan
Sarah L Cowan
Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
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Kevin Taylor
Kevin Taylor
Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
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Robert J B Goudie
Robert J B Goudie
MRC Biostatistics Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK
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Jacobus Preller
Jacobus Preller
Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
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Mark Gurnell
Mark Gurnell
Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
Wellcome–MRC Institute of Metabolic Science, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Addenbrooke’s Hospital, Cambridge, UK
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Wellcome–MRC Institute of Metabolic Science, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Addenbrooke’s Hospital, Cambridge, UK
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COVID-19 patients ( 7 ), the evidence regarding RAAS activation is less clear. Early studies found evidence of increased RAAS activation ( 8 , 9 , 10 ), but subsequent reports suggested no association ( 11 ). Similarly, there is conflicting evidence
Avinaash Maharaj
Avinaash Maharaj
Centre for Endocrinology, John Vane Science Centre, Queen Mary University of London, London, UK
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Ruth Kwong
Ruth Kwong
Centre for Endocrinology, John Vane Science Centre, Queen Mary University of London, London, UK
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Jack Williams
Jack Williams
Centre for Endocrinology, John Vane Science Centre, Queen Mary University of London, London, UK
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Christopher Smith
Christopher Smith
Centre for Endocrinology, John Vane Science Centre, Queen Mary University of London, London, UK
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Helen Storr
Helen Storr
Centre for Endocrinology, John Vane Science Centre, Queen Mary University of London, London, UK
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Ruth Krone
Ruth Krone
Birmingham Children’s Hospital, Birmingham, UK
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Debora Braslavsky
Debora Braslavsky
Centro de Investigaciones Endocrinológicas ‘Dr. Cesar Bergadá’ (CEDIE) – CONICET – FEI – División de Endocrinología, Hospital de Niños ‘Ricardo Gutiérrez’, Buenos Aires, Argentina
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Maria Clemente
Maria Clemente
Paediatric Endocrinology, Growth and Development Research Unit, Vall d’Hebron Research Institute (VHIR), Hospital Vall d’Hebron, CIBERER, Instituto de Salud Carlos III, Barcelona, Spain
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Nanik Ram
Nanik Ram
Department of Endocrinology, The Aga Khan University Hospital, Karachi, Pakistan
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Indraneel Banerjee
Indraneel Banerjee
Department of Paediatric Endocrinology, Royal Manchester Children’s Hospital, Manchester, UK
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Semra Çetinkaya
Semra Çetinkaya
Health Sciences University, Dr. Sami Ulus Obstetrics and Gynaecology, Children’s Health and Disease Education and Research Hospital, Ankara, Turkey
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Federica Buonocore
Federica Buonocore
Genetics and Genomic Medicine Research and Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK
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Tülay Güran
Tülay Güran
Department of Paediatric Endocrinology and Diabetes, Marmara University, School of Medicine, Istanbul, Turkey
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John C Achermann
John C Achermann
Genetics and Genomic Medicine Research and Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK
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Louise Metherell
Louise Metherell
Centre for Endocrinology, John Vane Science Centre, Queen Mary University of London, London, UK
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Rathi Prasad
Rathi Prasad
Centre for Endocrinology, John Vane Science Centre, Queen Mary University of London, London, UK
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50 patients with SPLIS ( Fig. 3 ). PAI is the most common endocrine manifestation of the disease and indeed one of the most predominant clinical features overall. Thirty-two patients (64% of the 50 patients) presented with biochemical evidence of PAI
Deirdre Green
Deirdre Green
Academic Department of Endocrinology, Beaumont Hospital and the Royal College of Surgeons in Ireland, Dublin
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Rosemary Dineen
Rosemary Dineen
Academic Department of Endocrinology, Beaumont Hospital and the Royal College of Surgeons in Ireland, Dublin
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Michael W O’Reilly
Michael W O’Reilly
Academic Department of Endocrinology, Beaumont Hospital and the Royal College of Surgeons in Ireland, Dublin
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Mark Sherlock
Mark Sherlock
Academic Department of Endocrinology, Beaumont Hospital and the Royal College of Surgeons in Ireland, Dublin
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physiological alterations in cortisol secretion and cortisol binding globulin during pregnancy affect both clinical and biochemical evaluation ( 18 ). Furthermore, there is a paucity of evidence-based data on optimal adrenal hormone adjustment during pregnancy
Susan M Webb
Susan M Webb
IIB-Sant Pau, Research Center for Pituitary Diseases, Barcelona, Spain
Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER, Unidad 747), ISCIII, Spain
Department of Endocrinology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
Department of Medicine, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain
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Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER, Unidad 747), ISCIII, Spain
Department of Endocrinology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
Department of Medicine, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain
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Jette Kristensen
Jette Kristensen
ePAG & Chair of Danish Addison Patient Association, Aarhus, Denmark
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Anna Nordenström
Anna Nordenström
Pediatric Endocrinology, Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden
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Diana Vitali
Diana Vitali
ePAG & Chair SOD ITALIA - Italian Patients Organization for Septo Optic Dysplasia and other Neuroendocrine Conditions, Rome, Italy
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Vincent Amodru
Vincent Amodru
Aix-Marseille Université, Institut National de la Santé et de la Recherche Médicale (INSERM), U1251, Marseille Medical Genetics, Institut MarMaRa, Marseille, France
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Lenja Katharina Wiehe
Lenja Katharina Wiehe
EURORDIS - Rare Diseases Europe, Paris, France
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Matt Bolz-Johnson
Matt Bolz-Johnson
EURORDIS - Rare Diseases Europe, Paris, France
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. Furthermore, a recent systematic review of patient privacy perspectives related to health information exchange has evidenced that perceived quality of care was associated with few privacy concerns; in other words, positive patient perceptions on healthcare and
