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loss of libido and sexual function as major side effects. However, no testosterone also means no estradiol (E2), since all E2 in the human body is synthesized by aromatization of its precursor testosterone. Since E2 is by far the most potent and
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141. ( https://doi.org/10.3389/fendo.2018.00141 ) 53 Singhal V Karzar NH Bose A Buckless C Ackerman KE Bredella MA Klibanski A Misra M . Changes in marrow adipose tissue in relation to changes in bone parameters following estradiol