Bjarke R Medici
Bjarke R Medici
Department of Medicine, Herlev Hospital, University of Copenhagen, Herlev, Denmark
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
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Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
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Birte Nygaard
Birte Nygaard
Department of Medicine, Herlev Hospital, University of Copenhagen, Herlev, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Jeppe L la Cour
Jeppe L la Cour
Department of Medicine, Herlev Hospital, University of Copenhagen, Herlev, Denmark
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Martin Krakauer
Martin Krakauer
Department of Clinical Physiology and Nuclear Medicine, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Department of Clinical Physiology and Nuclear Medicine, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Physiology and Nuclear Medicine, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark
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Andreas Brønden
Andreas Brønden
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Department of Clinical Pharmacology, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Pharmacology, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark
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Mette P Sonne
Mette P Sonne
Department of Medicine, Herlev Hospital, University of Copenhagen, Herlev, Denmark
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Jens J Holst
Jens J Holst
Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Jens F Rehfeld
Jens F Rehfeld
Department of Clinical Biochemistry, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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Tina Vilsbøll
Tina Vilsbøll
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Steno Diabetes Center Copenhagen, Herlev, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Steno Diabetes Center Copenhagen, Herlev, Denmark
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Jens Faber
Jens Faber
Department of Medicine, Herlev Hospital, University of Copenhagen, Herlev, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Filip K Knop
Filip K Knop
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Steno Diabetes Center Copenhagen, Herlev, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Steno Diabetes Center Copenhagen, Herlev, Denmark
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mass index (BMI) ( 4 , 5 ), and several factors have been proposed to contribute to this association such as fluid retention ( 6 ), reduced resting energy expenditure (REE) ( 7 ), and reduction in physical activity ( 8 ). Despite the common assumption
Huixing Liu
Huixing Liu
Department of Cardiovascular Medicine, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China
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Daoquan Peng
Daoquan Peng
Department of Cardiovascular Medicine, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China
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energy metabolism by activating the AMPK-SIRT1-PGC-1alpha pathway . PNAS 2010 107 12553 – 12558 . ( https://doi.org/10.1073/pnas.1006962107 ) 74 Iizuka K Takao K Kato T Horikawa Y Takeda J . ChREBP reciprocally regulates liver and plasma
Shi-en Fu
Shi-en Fu
Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Rou-mei Wang
Rou-mei Wang
Department of Ultrasonic Diagnosis, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Xing-huan Liang
Xing-huan Liang
Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Jing Xian
Jing Xian
Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Jie Pan
Jie Pan
Department of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Xue-lan Chen
Xue-lan Chen
Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Cheng-cheng Qiu
Cheng-cheng Qiu
Department of Ultrasonic Diagnosis, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Zhi-ping Tang
Zhi-ping Tang
Department of Ultrasonic Diagnosis, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Ying-fen Qin
Ying-fen Qin
Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Hai-yan Yang
Hai-yan Yang
Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Li-li Huang
Li-li Huang
Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
Department of Endocrinology, The Affiliated Hospital of Guilin Medical University, Guilin, China
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Department of Endocrinology, The Affiliated Hospital of Guilin Medical University, Guilin, China
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Ya-qi Kuang
Ya-qi Kuang
Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Yan Ma
Yan Ma
Department of Ultrasonic Diagnosis, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Zuo-jie Luo
Zuo-jie Luo
Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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that coupled oxidative phosphorylation and uncoupled respiration may play an important role in the impairment of mitochondrial energy metabolism in skeletal muscles ( 49 , 50 ). Excess thyroid hormone levels accelerate protein catabolism and reduce
Yukari Maki
Yukari Maki
Department of Pediatric Surgery, Tokyo Women’s Medical University, Shinjuku-ku, Tokyo, Japan
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Kiyomi Horiuchi
Kiyomi Horiuchi
Department of Endocrine Surgery, Tokyo Women’s Medical University, Shinjuku-ku, Tokyo, Japan
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Takahiro Okamoto
Takahiro Okamoto
Department of Endocrine Surgery, Tokyo Women’s Medical University, Shinjuku-ku, Tokyo, Japan
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patients on levothyroxine monotherapy have a low serum fT3 level, and those with a normal serum TSH level were not necessarily euthyroid in terms of energy expenditure, lipid metabolism, dissatisfaction, or quality of life, including fatigue ( 36 , 37
Qiankai Jin
Qiankai Jin
Department of Endocrinology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, China
School of Medicine, Ningbo University, Ningbo, China
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School of Medicine, Ningbo University, Ningbo, China
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Guoqing Huang
Guoqing Huang
Department of Endocrinology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, China
School of Medicine, Ningbo University, Ningbo, China
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School of Medicine, Ningbo University, Ningbo, China
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Xiaoqing Tian
Xiaoqing Tian
Department of Endocrinology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, China
School of Medicine, Ningbo University, Ningbo, China
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School of Medicine, Ningbo University, Ningbo, China
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Yimeng Shu
Yimeng Shu
Department of Endocrinology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, China
School of Medicine, Ningbo University, Ningbo, China
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School of Medicine, Ningbo University, Ningbo, China
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Ximisinuer Tusongtuoheti
Ximisinuer Tusongtuoheti
Department of Endocrinology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, China
School of Medicine, Ningbo University, Ningbo, China
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School of Medicine, Ningbo University, Ningbo, China
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Yushan Mao
Yushan Mao
Department of Endocrinology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, China
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MetS ( 4 ). Thyroid hormones (THs) are vital hormones that regulate the metabolism of substances ( 5 ) and therefore affect MetS and its components by regulating energy homeostasis, lipid metabolism, and gluconeogenesis. However, the association
Sophie-Charlotte Drogge
Sophie-Charlotte Drogge
Institute of Medical Informatics, Biometry and Epidemiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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Mirjam Frank
Mirjam Frank
Institute of Medical Informatics, Biometry and Epidemiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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Carolin Girschik
Carolin Girschik
Institute of Medical Informatics, Biometry and Epidemiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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Karl-Heinz Jöckel
Karl-Heinz Jöckel
Institute of Medical Informatics, Biometry and Epidemiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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Dagmar Führer-Sakel
Dagmar Führer-Sakel
Department of Endocrinology, Diabetes and Metabolism, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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Börge Schmidt
Börge Schmidt
Institute of Medical Informatics, Biometry and Epidemiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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Introduction Thyroid hormones play an important role in almost all biological processes in humans such as energy metabolism, cell growth, development, cardiovascular system, CNS, immunity and bone metabolism ( 1 , 2 ). Importantly, several
