Department of Medicine, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland
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Department of Medicine, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland
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Department of Medicine, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland
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Department of Medicine, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland
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Department of Medicine, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland
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Thr 308 were inhibited with lactone-form simvastatin, suggesting an Akt-independent mechanism for phosphorylation of AS160 and GSK3β with lactone-form simvastatin. In order to get more detailed insight into the glucose metabolism in terms of energy
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Introduction White adipose tissue (WAT) is a metabolically active tissue that modifies systemic metabolism significantly by regulating the storage and release of lipids. Free fatty acids serve as a major fuel source during times of energy
Department of Medicine, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland
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Department of Medicine, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland
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Department of Medicine, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland
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Department of Medicine, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland
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Department of Medicine, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland
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that results in increased energy wasting and body weight loss in humans is yet to be shown. Function of human BAT: relevance for energy metabolism Soon after the detection of cold-induced BAT in human adults in 2009, numerous follow-up studies
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metabolism. Kiss1 neurons as metabolic gates of fertility Kiss1 neurons are critical regulatory nodes that integrate metabolic cues in order to adjust reproductive function to energy stores. A number of studies have characterized the inhibitory effect
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mineral density (BMD) followed by multiple low-energy fractures. In contrast to sporadic PHPT, bone disorders in patients with PHPT in multiple endocrine neoplasias (PHPT/MEN1) are more severe. The higher severity of bone and mineral disorders in patients
Institute of Clinical Research, University of Southern Denmark, Odense, Denmark
Department of Endocrinology, Hospital of Southwest Jutland, Esbjerg, Denmark
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Institute of Clinical Research, University of Southern Denmark, Odense, Denmark
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Steno Diabetes Center Odense, Odense University Hospital, Odense, Denmark
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Steno Diabetes Center Odense, Odense University Hospital, Odense, Denmark
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muscle is inversely correlated to age of diabetes debut ( 14 ). It is debated whether the impaired glucose metabolism in m.3243A>G carriers is characterized by insulin resistance, insulin secretion defect or a combination. The nuclear gene encoded
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Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway
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Steno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, Denmark
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, 9 ). Other studies indicate that EPO has effects on lipid and energy metabolism. However, the mechanisms behind these effects remain unclear ( 10 , 11 , 12 , 13 ). Treatment with rHuEpo has been reported to improve insulin sensitivity and
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downstream regulators ( 45 , 24 ). This interference of peripheral TH function in tissues, quantitatively important in energy metabolism, is in line with the observation that HIGH:CONV sheep did not increase their heart rate in response to a thyroxine surge
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from anterior pituitary and named for its crucial effect on lactation ( 8 , 9 ). Recent studies have demonstrated that PRL plays an important role in regulating energy metabolism ( 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 ). PRL administration