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condition. Consequently, as in certain hereditary endocrine diseases for example, the skin can also provide information about the severity of the underlying disease or can even be indicative of the condition itself. Diseases of endocrine organs often lead to
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proliferation by TSH and other factors: a critical evaluation of in vitro models . Endocrine Reviews 2001 22 631 – 656 . ( https://doi.org/10.1210/edrv.22.5.0444 ) 40 Tian L Ni J Guo T Liu J Dang Y Guo Q Zhang L . TSH stimulates the
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Global Health Research Institute, School of Human Development and Health, University of Southampton, Southampton, UK
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Introduction Adipose tissue is a functioning endocrine organ that produces a number of circulating hormones, including adiponectin. Unlike other adipokines, adiponectin levels fall with increasing total body fat mass ( 1 , 2 ). In addition
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quantitative importance of other factors, such as inhibition by insulin and stimulation by amino acids, is disputed ( 8 , 9 ). Hypoglycemia also triggers the release of other counter-regulatory hormones such as catecholamines, cortisol, and growth hormone
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– 1078 . ( https://doi.org/10.2337/db17-0706 ) 15 Lu CF Ma JH Su JB Wang XQ Liu WS Ge XQ . XQSerum stromal cell-derived factor-1 levels are associated with diabetic kidney disease in type 2 diabetic patients . Endocrine Journal 2021 68
Department of Anatomy, Shanxi Medical University, Taiyuan, China
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an adaptive process to insulin deficiency remains unclear. In healthy individuals, the number of β cells is maintained by neogenesis of endocrine progenitor cells, reprogramming of non-β cells or replication of pre-existing β cells ( 5 , 6 , 7
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( 3 , 4 ). It is noteworthy that approximately 20% of individuals diagnosed with diabetes mellitus may experience a progression to DKD ( 5 ), a condition which has emerged as the primary etiological factor underlying end-stage renal disease (ESRD) in
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polycystic ovary syndrome . Endocrine 2009 36 326 – 332 . ( https://doi.org/10.1007/s12020-009-9226-7 ) 28 Wei HJ Young R Kuo IL Liaw CM Chiang HS Yeh CY . Prevalence of insulin resistance and determination of risk factors for glucose
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fat distribution or fat content within the body. Ectopic fat accumulation is regarded as a risk factor for metabolic diseases ( 3 , 4 ). Our team recently demonstrated that visceral adipose tissue (VAT) and fat content of the liver in overweight
Department of Endocrinology, Austin Health, Melbourne, Australia
Division of Endocrinology, Diabetes and Metabolism, Northwell, Great Neck, New York, USA
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Department of Cardiology, Austin Health, Melbourne Australia
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causes of mortality is death from cardiovascular disease (CVD) ( 5 ). The mechanism for this increased mortality is likely multifactorial and includes the higher prevalence of CVD risk factors in cancer survivors and the cardiotoxic effects of breast