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E K White
E K White
Division of Endocrinology and Centre for Endocrine Tumors, Department of Medicine, Leiden University Medical Centre, Leiden, The Netherlands
Faculty of Medicine Division 2, Internal Medicine Endocrinology, Leiden University Medical Centre, Leiden, The Netherlands
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Faculty of Medicine Division 2, Internal Medicine Endocrinology, Leiden University Medical Centre, Leiden, The Netherlands
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I V Wagner
I V Wagner
Department of Endocrinology & Metabolism, Amsterdam University Medical Centre, Amsterdam, The Netherlands
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C van Beuzekom
C van Beuzekom
Division of Endocrinology and Centre for Endocrine Tumors, Department of Medicine, Leiden University Medical Centre, Leiden, The Netherlands
Faculty of Medicine Division 2, Internal Medicine Endocrinology, Leiden University Medical Centre, Leiden, The Netherlands
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Faculty of Medicine Division 2, Internal Medicine Endocrinology, Leiden University Medical Centre, Leiden, The Netherlands
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V Iotova
V Iotova
Division of Paediatric Endocrinology and Diabetes, Department of Paediatrics and Adolescent Medicine, University of Lübeck, Lübeck, Germany
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S F Ahmed
S F Ahmed
Office for Rare Conditions, University of Glasgow, Glasgow, UK
Department of Paediatrics, UMHAT ‘Sveta Marina’ Varna, Medical University of Varna, Varna, Bulgaria
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Department of Paediatrics, UMHAT ‘Sveta Marina’ Varna, Medical University of Varna, Varna, Bulgaria
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O Hiort
O Hiort
Department of Endocrinology & Metabolism, Amsterdam University Medical Centre, Amsterdam, The Netherlands
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A M Pereira
A M Pereira
Faculty of Medicine Division 2, Internal Medicine Endocrinology, Leiden University Medical Centre, Leiden, The Netherlands
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patients with rare endocrine conditions. In our system usage statistics ( Fig. 2 ), we can see that the number of active users and panels has declined in 2021. Apart from the time factor which might be a strong hurdle to use the CPMS, the COVID-19
Hélène Singeisen
Hélène Singeisen
Department of Internal Medicine, Endocrinology, Cantonal Hospital Thurgau, Münsterlingen, Switzerland
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Mariko Melanie Renzulli
Mariko Melanie Renzulli
Institute of Radiology, Cantonal Hospital Thurgau, Frauenfeld, Switzerland
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Vojtech Pavlicek
Vojtech Pavlicek
Department of Internal Medicine, Endocrinology, Cantonal Hospital Thurgau, Münsterlingen, Switzerland
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Pascal Probst
Pascal Probst
Department of Surgery, Cantonal Hospital Thurgau, Frauenfeld, Switzerland
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Fabian Hauswirth
Fabian Hauswirth
Department of Surgery, Cantonal Hospital Thurgau, Münsterlingen, Switzerland
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Markus K Muller
Markus K Muller
Department of Surgery, Cantonal Hospital Thurgau, Frauenfeld, Switzerland
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Magdalene Adamczyk
Magdalene Adamczyk
Department of Pathology and Molecular Pathology, University Hospital Zurich and University of Zurich, Zurich, Switzerland
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Achim Weber
Achim Weber
Department of Pathology and Molecular Pathology, University Hospital Zurich and University of Zurich, Zurich, Switzerland
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Reto Martin Kaderli
Reto Martin Kaderli
Department of Visceral Surgery and Medicine, Bern University Hospital, University of Bern, Bern, Switzerland
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Pietro Renzulli
Pietro Renzulli
Department of Surgery, Cantonal Hospital Thurgau, Münsterlingen, Switzerland
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. Such a cluster of endocrine diseases in a single person will eventually raise the suspicion of an underlying genetic mutation. A positive family history will further underline the need for genetic testing. The CDKN1B mutation as a causative factor
Hanna Karhapää
Hanna Karhapää
Medical Faculty, University of Helsinki, Helsinki, Finland
Department of Oncology, Comprehensive Cancer Centre, Helsinki University Hospital, Helsinki, Finland
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Department of Oncology, Comprehensive Cancer Centre, Helsinki University Hospital, Helsinki, Finland
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Siru Mäkelä
Siru Mäkelä
Medical Faculty, University of Helsinki, Helsinki, Finland
Department of Oncology, Comprehensive Cancer Centre, Helsinki University Hospital, Helsinki, Finland
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Department of Oncology, Comprehensive Cancer Centre, Helsinki University Hospital, Helsinki, Finland
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Hanna Laurén
Hanna Laurén
Medical Faculty, University of Helsinki, Helsinki, Finland
Department of Radiology, HUS Medical Imaging Centre, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
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Department of Radiology, HUS Medical Imaging Centre, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
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Marjut Jaakkola
Marjut Jaakkola
Medical Faculty, University of Helsinki, Helsinki, Finland
Department of Radiology, HUS Medical Imaging Centre, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
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Department of Radiology, HUS Medical Imaging Centre, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
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Camilla Schalin-Jäntti
Camilla Schalin-Jäntti
Medical Faculty, University of Helsinki, Helsinki, Finland
Endocrinology, Abdominal Centre, University of Helsinki and HUS, Helsinki, Finland
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Endocrinology, Abdominal Centre, University of Helsinki and HUS, Helsinki, Finland
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Micaela Hernberg
Micaela Hernberg
Medical Faculty, University of Helsinki, Helsinki, Finland
Department of Oncology, Comprehensive Cancer Centre, Helsinki University Hospital, Helsinki, Finland
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Department of Oncology, Comprehensive Cancer Centre, Helsinki University Hospital, Helsinki, Finland
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. ICIs can generate autoimmune-like reactions towards one or multiple organs, including the gastrointestinal tract, skin, and endocrine glands ( 5 ). These AEs are classified as immune-related AEs (irAEs) and their seriousness varies from transient
Anna Gorbacheva
Anna Gorbacheva
Endocrinology Research Center, Moscow, Russian Federation
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Anna Eremkina
Anna Eremkina
Endocrinology Research Center, Moscow, Russian Federation
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Daria Goliusova
Daria Goliusova
Endocrinology Research Center, Moscow, Russian Federation
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Julia Krupinova
Julia Krupinova
Endocrinology Research Center, Moscow, Russian Federation
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Natalia Mokrysheva
Natalia Mokrysheva
Endocrinology Research Center, Moscow, Russian Federation
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intracellular signaling. Mutations in the menin gene cause the development of multiple endocrine neoplasia type 1 (MEN1) syndrome. This autosomal dominant disease is characterized by the formation of multiple tumors, predominantly located in the endocrine glands
Nikolaos Kyriakakis
Nikolaos Kyriakakis
Department of Endocrinology, Leeds Centre for Diabetes & Endocrinology, Leeds Teaching Hospitals NHS Trust, Leeds, UK
Leeds Institute for Cardiovascular and Metabolic Medicine (LICAMM), University of Leeds, Leeds, UK
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Leeds Institute for Cardiovascular and Metabolic Medicine (LICAMM), University of Leeds, Leeds, UK
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Marilena Giannoudi
Marilena Giannoudi
Department of Endocrinology, Leeds Centre for Diabetes & Endocrinology, Leeds Teaching Hospitals NHS Trust, Leeds, UK
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Satish S Kumar
Satish S Kumar
Department of Endocrinology, Leeds Centre for Diabetes & Endocrinology, Leeds Teaching Hospitals NHS Trust, Leeds, UK
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Khyatisha Seejore
Khyatisha Seejore
Department of Endocrinology, Leeds Centre for Diabetes & Endocrinology, Leeds Teaching Hospitals NHS Trust, Leeds, UK
Leeds Institute for Cardiovascular and Metabolic Medicine (LICAMM), University of Leeds, Leeds, UK
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Leeds Institute for Cardiovascular and Metabolic Medicine (LICAMM), University of Leeds, Leeds, UK
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Georgios K Dimitriadis
Georgios K Dimitriadis
Department of Endocrinology, King’s College Hospital NHS Foundation Trust, Denmark Hill, London, UK
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Harpal Randeva
Harpal Randeva
Warwickshire Institute for the Study of Diabetes, Endocrinology and Metabolism (WISDEM), University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK
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Adam Glaser
Adam Glaser
Pediatric Oncology, Leeds General Infirmary, Leeds Teaching Hospitals NHS Trust, Leeds, UK
Leeds Institute of Medical Research, University of Leeds, UK
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Leeds Institute of Medical Research, University of Leeds, UK
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Michelle Kwok-Williams
Michelle Kwok-Williams
Clinical Oncology, Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UK
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Georgina Gerrard
Georgina Gerrard
Clinical Oncology, Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UK
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Carmel Loughrey
Carmel Loughrey
Clinical Oncology, Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UK
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Ahmed Al-Qaissi
Ahmed Al-Qaissi
Department of Endocrinology, Leeds Centre for Diabetes & Endocrinology, Leeds Teaching Hospitals NHS Trust, Leeds, UK
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Ramzi Ajjan
Ramzi Ajjan
Leeds Institute for Cardiovascular and Metabolic Medicine (LICAMM), University of Leeds, Leeds, UK
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Julie Lynch
Julie Lynch
Department of Endocrinology, Leeds Centre for Diabetes & Endocrinology, Leeds Teaching Hospitals NHS Trust, Leeds, UK
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Robert D Murray
Robert D Murray
Department of Endocrinology, Leeds Centre for Diabetes & Endocrinology, Leeds Teaching Hospitals NHS Trust, Leeds, UK
Leeds Institute for Cardiovascular and Metabolic Medicine (LICAMM), University of Leeds, Leeds, UK
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Leeds Institute for Cardiovascular and Metabolic Medicine (LICAMM), University of Leeds, Leeds, UK
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the primary disease; however, an increase in cardiovascular mortality ( 3 ) and risk of early and late-occurring stroke ( 4 , 5 ) are also observed. There are limited cross-sectional studies evaluating conventional vascular risk factors in SCBT ( 6
Ruth Percik
Ruth Percik
Institute of Endocrinology, Diabetes and Metabolism, Sheba Medical Centre, Ramat Gan, Israel
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Sherwin Criseno
Sherwin Criseno
Department of Endocrinology, University Hospital Birmingham, Birmingham, UK
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Safwaan Adam
Safwaan Adam
Department of Endocrinology, The Christie NHS Foundation Trust, Manchester, UK
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Kate Young
Kate Young
Royal Marsden Hospital, London, UK
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Daniel L Morganstein
Daniel L Morganstein
Department of Endocrinology, Chelsea and Westminster Hospital, London, UK
Royal Marsden Hospital, London, UK
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Royal Marsden Hospital, London, UK
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– death) and guide decisions regarding continuation of immunotherapy and need for an immunomodulatory intervention ( Table 1 ). Table 1 CTCAEv5 classification of endocrine dysfunction. CTCAE Toxicity Grade 1 2 3 4 5
Vita Birzniece
Vita Birzniece
School of Medicine, Western Sydney University, New South Wales, Australia
Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
Garvan Institute of Medical Research, New South Wales, Australia
School of Medical Sciences, University of New South Wales, New South Wales, Australia
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Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
Garvan Institute of Medical Research, New South Wales, Australia
School of Medical Sciences, University of New South Wales, New South Wales, Australia
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Teresa Lam
Teresa Lam
School of Medicine, Western Sydney University, New South Wales, Australia
Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
Department of Diabetes and Endocrinology, Westmead Hospital, New South Wales, Australia
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Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
Department of Diabetes and Endocrinology, Westmead Hospital, New South Wales, Australia
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Mark McLean
Mark McLean
School of Medicine, Western Sydney University, New South Wales, Australia
Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
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Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
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Navneeta Reddy
Navneeta Reddy
Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
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Haleh Shahidipour
Haleh Shahidipour
School of Medicine, Western Sydney University, New South Wales, Australia
Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
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Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
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Amy Hayden
Amy Hayden
School of Medicine, Western Sydney University, New South Wales, Australia
Faculty of Medicine, Health and Human Sciences, Macquarie University, New South Wales, Australia
Crown Princess Mary Cancer Centre, Westmead Hospital, New South Wales, Australia
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Faculty of Medicine, Health and Human Sciences, Macquarie University, New South Wales, Australia
Crown Princess Mary Cancer Centre, Westmead Hospital, New South Wales, Australia
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Howard Gurney
Howard Gurney
Crown Princess Mary Cancer Centre, Westmead Hospital, New South Wales, Australia
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Glenn Stone
Glenn Stone
School of Computing, Engineering and Mathematics, Western Sydney University, New South Wales, Australia
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Rikke Hjortebjerg
Rikke Hjortebjerg
Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
Endocrine Research Unit, Department of Endocrinology, Odense University Hospital & Department of Clinical Research, Faculty of Health, University of Southern Denmark, Odense, Denmark
Steno Diabetes Center Odense, Odense University Hospital & Department of Clinical Research, Faculty of Health, University of Southern Denmark, Odense, Denmark
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Endocrine Research Unit, Department of Endocrinology, Odense University Hospital & Department of Clinical Research, Faculty of Health, University of Southern Denmark, Odense, Denmark
Steno Diabetes Center Odense, Odense University Hospital & Department of Clinical Research, Faculty of Health, University of Southern Denmark, Odense, Denmark
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Jan Frystyk
Jan Frystyk
Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
Endocrine Research Unit, Department of Endocrinology, Odense University Hospital & Department of Clinical Research, Faculty of Health, University of Southern Denmark, Odense, Denmark
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Endocrine Research Unit, Department of Endocrinology, Odense University Hospital & Department of Clinical Research, Faculty of Health, University of Southern Denmark, Odense, Denmark
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poorer cancer prognosis ( 1 , 2 ). Chronic hyperinsulinemia may stimulate carcinogenesis either directly through the insulin receptor or indirectly through insulin-like growth factor receptors (IGF-1Rs). Recent evidence indicates that the anti
Arnaud Lagarde
Arnaud Lagarde
Aix Marseille Univ, APHM, INSERM, MMG, Laboratory of Molecular Biology Hospital La Conception, Marseille, France
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Grégory Mougel
Grégory Mougel
Aix Marseille Univ, APHM, INSERM, MMG, Laboratory of Molecular Biology Hospital La Conception, Marseille, France
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Lucie Coppin
Lucie Coppin
Univ. Lille, CNRS, Inserm, CHU Lille, UMR9020-U1277 – CANTHER – Cancer – Heterogeneity Plasticity and Resistance to Therapies, Lille, France
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Magalie Haissaguerre
Magalie Haissaguerre
Service d’Endocrinologie, Centre Hospitalier Universitaire, Hôpital du Haut Levêque, Pessac, France
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Lauriane Le Collen
Lauriane Le Collen
Endocrinology, Diabetology and Nutrition Unit, University Hospital of Reims, Reims, France
Inserm/CNRS UMR 1283/8199, Pasteur Institute of Lille, EGID, Lille, France
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Inserm/CNRS UMR 1283/8199, Pasteur Institute of Lille, EGID, Lille, France
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Amira Mohamed
Amira Mohamed
Laboratory of Molecular Biology, Hospital La Conception, APHM, Marseille, France
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Marc Klein
Marc Klein
Service Endocrinologie, CHU de Nancy, Hôpital de Brabois, Vandoeuvre-lès-Nancy, France
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Marie-Françoise Odou
Marie-Françoise Odou
CHU Lille, Service de Biochimie et Biologie Moléculaire ‘Hormonologie, Métabolisme-Nutrition, Oncologie’, Lille, France
Univ. Lille, Inserm, CHU Lille, U1286 – Infinite – Institute for Translational Research in Inflammation, Lille, France
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Univ. Lille, Inserm, CHU Lille, U1286 – Infinite – Institute for Translational Research in Inflammation, Lille, France
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Antoine Tabarin
Antoine Tabarin
Service d’Endocrinologie, Centre Hospitalier Universitaire, Hôpital du Haut Levêque, Pessac, France
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Hedia Brixi
Hedia Brixi
Department of Gastroenterology and Digestive Oncology, Reims University Hospital, Reims, France
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Thomas Cuny
Thomas Cuny
Aix Marseille Univ, APHM, INSERM, MMG, Department of Endocrinology, Hospital La Conception, Marseille, France
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Brigitte Delemer
Brigitte Delemer
Endocrinology, Diabetology and Nutrition Unit, University Hospital of Reims, Reims, France
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Anne Barlier
Anne Barlier
Aix Marseille Univ, APHM, INSERM, MMG, Laboratory of Molecular Biology Hospital La Conception, Marseille, France
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Pauline Romanet
Pauline Romanet
Aix Marseille Univ, APHM, INSERM, MMG, Laboratory of Molecular Biology Hospital La Conception, Marseille, France
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-Bauters C Costa A Ruszniewski P Niccoli P Ménégaux F Chabrier G Borson-Chazot F Risk factors and causes of death in MEN1 disease. A GTE (Groupe d’Etude des tumeurs endocrines) cohort study among 758 patients . World Journal of Surgery 2010 34
Malgorzata Fuksiewicz
Malgorzata Fuksiewicz
Laboratory of Tumor Markers, Department of Pathology and Laboratory Diagnostics, The Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland
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Maria Kowalska
Maria Kowalska
Laboratory of Tumor Markers, Department of Pathology and Laboratory Diagnostics, The Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland
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Agnieszka Kolasinska-Cwikla
Agnieszka Kolasinska-Cwikla
Department of Oncology and Radiotherapy, The Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland
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Beata Kotowicz
Beata Kotowicz
Laboratory of Tumor Markers, Department of Pathology and Laboratory Diagnostics, The Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland
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prostate cancer may be associated with a component of neuroendocrine cells in adenocarcinoma or with the initiated process of transformation of cancer cells in the neuroendocrine direction. Elevated NSE levels are among the unfavourable prognostic factors
Jiaxin Luo
Jiaxin Luo
Department of Nuclear Medicine, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong Province, China
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Weili Yin
Weili Yin
Department of Nuclear Medicine, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong Province, China
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Qiuxia Lin
Qiuxia Lin
The Second School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong Province, China
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Juqing Wu
Juqing Wu
Department of Nuclear Medicine, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong Province, China
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Pan Chen
Pan Chen
Department of Nuclear Medicine, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong Province, China
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Yuanna Ling
Yuanna Ling
Department of Nuclear Medicine, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong Province, China
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Jing Wang
Jing Wang
Department of Nuclear Medicine, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong Province, China
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Zhen Li
Zhen Li
Department of Nuclear Medicine, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong Province, China
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Liqin Pan
Liqin Pan
Department of Nuclear Medicine, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong Province, China
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Yanying Chen
Yanying Chen
Department of Nuclear Medicine, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong Province, China
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Wei Ouyang
Wei Ouyang
Department of Nuclear Medicine, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong Province, China
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Huijuan Feng
Huijuan Feng
Department of Nuclear Medicine, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong Province, China
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(LPFS) of bone foci. Given the negative impact of SREs on the quality of life, it is necessary to pay attention to the LPFS. In this study, the clinical characteristics of DTC bone metastases were described and analyzed so as to determine the factors
