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half of them present with additional autoimmune diseases ( 5 , 6 , 7 ). This particular trait suggests an inborn immune defect, which potentially may be transmitted within their families. However, most of the autoimmune endocrine diseases, including
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University of Glasgow, Office for Rare Conditions, Glasgow, UK
University of Glasgow, Developmental Endocrinology Research Group, Royal Hospital for Children, Glasgow, UK
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has been demonstrated that the primary risk factors associated with VTE include older age (>69 years), reduced mobility, acute severe infections, previous cardiovascular events, higher midnight plasma cortisol levels, and shorter activated partial
International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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Pediatric Endocrinology Clinic, Department of Pediatrics, Aretaeio Hospital, Nicosia, Cyprus
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Department of Clinical Medicine, University of Copenhagen, Denmark
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, as such other factors may most likely add to their development ( 6 ). The biochemical assessment of gonadal capability in male patients with CAH includes measurements of gonadotropins and testicular and adrenal hormones. The elevated adrenal
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replacement for endocrine dysfunction remain the mainstay of treatment. Exogenous administration of pyridoxine (Vitamin B6), a co-factor for S1P lyase, demonstrates some improvements in immunological profiles and absolute lymphocyte counts, for patients with
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Introduction The role of germline genetic factors in neuroendocrine/endocrine neoplasias has advanced significantly in recent decades with the identification of novel genetic causes for inheritable isolated and syndromic tumors. This is
Centre for Endocrinology and Metabolism, Hudson Institute of Medical Research, Victoria, Australia
Department of Endocrinology and Metabolism, BSMMU, Dhaka, Bangladesh
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Centre for Endocrinology and Metabolism, Hudson Institute of Medical Research, Victoria, Australia
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(PRC). Previously considered a rare disorder, it is now established as the most common cause of endocrine HTN and the single most important cause of treatment-resistant hypertension . The prevalence of PA ranges from 4.6% to 13.0% in patients with
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Division of Endocrinology, Diabetes and Metabolism, Department of Medical Sciences, University of Turin, Turin, Italy
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Department of Endocrinology, Karolinska University Hospital, Stockholm, Sweden
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Department of Medicine, Haukeland University Hospital, Bergen, Norway
Department of Medicine, Karolinska Institutet, Stockholm, Sweden
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Department of Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands
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transmembrane protease serine 2 precursor co-receptor by the lung, gastrointestinal system and kidneys, these elements are also highly expressed in endocrine tissues, such as the hypothalamus–pituitary–adrenal axis ( 4 ). It was previously shown that SARS
Facultad de Medicina, Universidad Complutense de Madrid, Madrid, España
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Servicio de Endocrinología y Nutrición. Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Hospital Clínico San Carlos, Madrid, España
Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Madrid, España
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Servicio de Endocrinología y Nutrición. Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Hospital Clínico San Carlos, Madrid, España
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in this condition. We have recently reported that HH is not infrequent in isolated acquired hypoaldosteronism, particularly when both factors inducing a low circulating level of aldosterone (such as heparin administration) and factors resulting in a
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Medical Research Council London Institute of Medical Sciences, London, UK
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Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
NIHR Birmingham Biomedical Research Centre, University of Birmingham and University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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from asymptomatic infection to acute respiratory distress syndrome, multiorgan failure and death. One key negative prognostic factor for severe COVID-19 is compromised immunity and increased infection risk ( 13 ); as such, patients with PAI are assumed
National Institute of Endocrinology CI Parhon, Bucharest, Romania
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National Institute of Endocrinology CI Parhon, Bucharest, Romania
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frequently described in the syndromes of multiple endocrine neoplasia (MEN) type 2A and type 2B, in certain families with von Hippel–Lindau disease ( VHL ) or in patients with MAX and TMEM127 gene mutation ( 3 , 7 ). Not all bilateral PHEOs are