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Mark J C van Treijen Department of Endocrine Oncology, University Medical Center Utrecht, Utrecht, The Netherlands
Center for Neuroendocrine Tumors, ENETS Center of Excellence, Netherlands Cancer Institute, University Medical Center Utrecht, Utrecht, The Netherlands

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Catharina M Korse Center for Neuroendocrine Tumors, ENETS Center of Excellence, Netherlands Cancer Institute, University Medical Center Utrecht, Utrecht, The Netherlands
Department of Clinical Chemistry, The Netherlands Cancer Institute, Amsterdam, The Netherlands

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Wieke H Verbeek Center for Neuroendocrine Tumors, ENETS Center of Excellence, Netherlands Cancer Institute, University Medical Center Utrecht, Utrecht, The Netherlands
Department of Gastroenterology, The Netherlands Cancer Institute, Amsterdam, The Netherlands

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Margot E T Tesselaar Center for Neuroendocrine Tumors, ENETS Center of Excellence, Netherlands Cancer Institute, University Medical Center Utrecht, Utrecht, The Netherlands
Department of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands

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Gerlof D Valk Department of Endocrine Oncology, University Medical Center Utrecht, Utrecht, The Netherlands
Center for Neuroendocrine Tumors, ENETS Center of Excellence, Netherlands Cancer Institute, University Medical Center Utrecht, Utrecht, The Netherlands

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increased over the past decades, most likely because of improvements in diagnostic techniques and disease awareness ( 1 , 2 , 3 ). GEPNETs are grouped based on their shared neuroendocrine markers and proteins, such as chromogranin and synaptophysin, but

Article Type:
Research Article
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Hormones and Cancer
DOI:
https://doi.org/10.1530/EC-22-0146
Volume/Issue:
Volume 11: Issue 10
Open access
Hélène Singeisen Department of Internal Medicine, Endocrinology, Cantonal Hospital Thurgau, Münsterlingen, Switzerland

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Mariko Melanie Renzulli Institute of Radiology, Cantonal Hospital Thurgau, Frauenfeld, Switzerland

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Vojtech Pavlicek Department of Internal Medicine, Endocrinology, Cantonal Hospital Thurgau, Münsterlingen, Switzerland

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Pascal Probst Department of Surgery, Cantonal Hospital Thurgau, Frauenfeld, Switzerland

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Fabian Hauswirth Department of Surgery, Cantonal Hospital Thurgau, Münsterlingen, Switzerland

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Markus K Muller Department of Surgery, Cantonal Hospital Thurgau, Frauenfeld, Switzerland

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Magdalene Adamczyk Department of Pathology and Molecular Pathology, University Hospital Zurich and University of Zurich, Zurich, Switzerland

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Achim Weber Department of Pathology and Molecular Pathology, University Hospital Zurich and University of Zurich, Zurich, Switzerland

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Reto Martin Kaderli Department of Visceral Surgery and Medicine, Bern University Hospital, University of Bern, Bern, Switzerland

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Pietro Renzulli Department of Surgery, Cantonal Hospital Thurgau, Münsterlingen, Switzerland

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-Vickers/Williams-Pollock/Wagenmann–Froboese syndrome --- --- OMIM ® #131100 #171400 #162300 #610755 --- Gene MEN1 RET RET CDKN1B MAX Location 11q13.1 10q11.21 10q11.21 12p13.1 14q23.3 Inheritance Autosomal-dominant Autosomal

Article Type:
Research Article
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Hormones and Cancer
DOI:
https://doi.org/10.1530/EC-22-0411
Volume/Issue:
Volume 12: Issue 2
Open access
Arnaud Lagarde Aix Marseille Univ, APHM, INSERM, MMG, Laboratory of Molecular Biology Hospital La Conception, Marseille, France

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Grégory Mougel Aix Marseille Univ, APHM, INSERM, MMG, Laboratory of Molecular Biology Hospital La Conception, Marseille, France

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Lucie Coppin Univ. Lille, CNRS, Inserm, CHU Lille, UMR9020-U1277 – CANTHER – Cancer – Heterogeneity Plasticity and Resistance to Therapies, Lille, France

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Magalie Haissaguerre Service d’Endocrinologie, Centre Hospitalier Universitaire, Hôpital du Haut Levêque, Pessac, France

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Lauriane Le Collen Endocrinology, Diabetology and Nutrition Unit, University Hospital of Reims, Reims, France
Inserm/CNRS UMR 1283/8199, Pasteur Institute of Lille, EGID, Lille, France

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Amira Mohamed Laboratory of Molecular Biology, Hospital La Conception, APHM, Marseille, France

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Marc Klein Service Endocrinologie, CHU de Nancy, Hôpital de Brabois, Vandoeuvre-lès-Nancy, France

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Marie-Françoise Odou CHU Lille, Service de Biochimie et Biologie Moléculaire ‘Hormonologie, Métabolisme-Nutrition, Oncologie’, Lille, France
Univ. Lille, Inserm, CHU Lille, U1286 – Infinite – Institute for Translational Research in Inflammation, Lille, France

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Antoine Tabarin Service d’Endocrinologie, Centre Hospitalier Universitaire, Hôpital du Haut Levêque, Pessac, France

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Hedia Brixi Department of Gastroenterology and Digestive Oncology, Reims University Hospital, Reims, France

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Thomas Cuny Aix Marseille Univ, APHM, INSERM, MMG, Department of Endocrinology, Hospital La Conception, Marseille, France

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Brigitte Delemer Endocrinology, Diabetology and Nutrition Unit, University Hospital of Reims, Reims, France

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Anne Barlier Aix Marseille Univ, APHM, INSERM, MMG, Laboratory of Molecular Biology Hospital La Conception, Marseille, France

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Pauline Romanet Aix Marseille Univ, APHM, INSERM, MMG, Laboratory of Molecular Biology Hospital La Conception, Marseille, France

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Introduction Multiple endocrine neoplasia type 1 (MEN1, OMIM 131100) is an autosomal dominant disease due to mutation in the MEN1 gene, characterized by a broad spectrum of clinical manifestations ( 1 ). The classic clinical triad includes

Article Type:
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Hormones and Cancer
DOI:
https://doi.org/10.1530/EC-22-0093
Volume/Issue:
Volume 11: Issue 11
Open access
Eleftherios E Deiktakis Laboratory of Clinical Chemistry, School of Medicine, University of Crete, Heraklion, Greece

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Eleftheria Ieronymaki Laboratory of Clinical Chemistry, School of Medicine, University of Crete, Heraklion, Greece

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Peter Zarén Department of Translational Medicine, Lund University, Malmö, Sweden

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Agnes Hagsund Department of Translational Medicine, Lund University, Malmö, Sweden

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Elin Wirestrand Department of Translational Medicine, Lund University, Malmö, Sweden

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Johan Malm Department of Translational Medicine, Lund University, Malmö, Sweden

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Christos Tsatsanis Laboratory of Clinical Chemistry, School of Medicine, University of Crete, Heraklion, Greece

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Ilpo T Huhtaniemi Department of Translational Medicine, Lund University, Malmö, Sweden
Imperial College London, Institute of Reproductive and Developmental Biology, London, UK

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Aleksander Giwercman Department of Translational Medicine, Lund University, Malmö, Sweden
Malmö University Hospital, Reproductive Medicine Center, Malmö, Sweden

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Yvonne Lundberg Giwercman Department of Translational Medicine, Lund University, Malmö, Sweden

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instrument (Roche Diagnostics). RNA extraction and real-time PCR on animal tissue Total RNA was isolated from the testis and prostate (including the seminal vesicles) tissues of the animals using TRIzol ® (Invitrogen) and the concentration was

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Hormones and Cancer
DOI:
https://doi.org/10.1530/EC-21-0639
Volume/Issue:
Volume 11: Issue 6
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Kazhan Mollazadegan Department of Medical Sciences, Uppsala University, Uppsala, Sweden

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Britt Skogseid Department of Medical Sciences, Uppsala University, Uppsala, Sweden

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Johan Botling Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden

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Tobias Åkerström Department of Surgical Sciences, Uppsala University, Uppsala, Sweden

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Barbro Eriksson Department of Medical Sciences, Uppsala University, Uppsala, Sweden

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Staffan Welin Department of Medical Sciences, Uppsala University, Uppsala, Sweden

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Anders Sundin Department of Surgical Sciences, Uppsala University, Uppsala, Sweden

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Joakim Crona Department of Medical Sciences, Uppsala University, Uppsala, Sweden

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0  IV 19  Unknown 1 Primary grade WHO 2017, n  G1 2  G2 20 Indication for new tumor sampling, n  Change of disease behavior 15  Diagnostic 7 Location of biopsy, n  Liver

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Hormones and Cancer
DOI:
https://doi.org/10.1530/EC-21-0604
Volume/Issue:
Volume 11: Issue 3
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Malgorzata Fuksiewicz Laboratory of Tumor Markers, Department of Pathology and Laboratory Diagnostics, The Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland

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Maria Kowalska Laboratory of Tumor Markers, Department of Pathology and Laboratory Diagnostics, The Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland

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Agnieszka Kolasinska-Cwikla Department of Oncology and Radiotherapy, The Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland

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Beata Kotowicz Laboratory of Tumor Markers, Department of Pathology and Laboratory Diagnostics, The Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland

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chromosomal rearrangements in the anaplastic lymphoma kinase gene show similar properties ( 6 , 7 ). The literature mainly presents the results of work on the clinical utility of NSE in patients with small cell lung cancer ( 8 , 9 ). The first studies

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Hormones and Cancer
DOI:
https://doi.org/10.1530/EC-21-0647
Volume/Issue:
Volume 11: Issue 9
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Peiwen Wu Department of Radiation Oncology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China

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Dongjie He Department of Radiation Oncology, Tangdu Hospital, the Second Affiliated Hospital of Air Force Medical University, Xi’an, China

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Hao Chang Department of Radiation Oncology, Tangdu Hospital, the Second Affiliated Hospital of Air Force Medical University, Xi’an, China

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Xiaozhi Zhang Department of Radiation Oncology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China

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increased from 1.09/100,000 to 6.98/100,000 between 1973 and 2012 in the USA ( 1 ); however, updated epidemiologic data are currently lacking. With improvements in diagnostic techniques ( 7 , 8 ), stage migration due to updated staging and grading

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Hormones and Cancer
DOI:
https://doi.org/10.1530/EC-23-0331
Volume/Issue:
Volume 12: Issue 12
Open access