Elena Valassi
Elena Valassi
Endocrinology Department, Germans Trias i Pujol Hospital and Research Institute, Badalona, Barcelona, Spain
IRCCS, Istituto Auxologico Italiano, Milan, Italy
Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
Search for other papers by Elena Valassi in
Google Scholar
PubMed
IRCCS, Istituto Auxologico Italiano, Milan, Italy
Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
Search for other papers by Elena Valassi in
Google Scholar
PubMed
Iacopo Chiodini
Iacopo Chiodini
IRCCS, Istituto Auxologico Italiano, Milan, Italy
Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
Search for other papers by Iacopo Chiodini in
Google Scholar
PubMed
Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
Search for other papers by Iacopo Chiodini in
Google Scholar
PubMed
Richard A Feelders
Richard A Feelders
Division of Endocrinology, Erasmus Medical Centre, Rotterdam, Netherlands
Search for other papers by Richard A Feelders in
Google Scholar
PubMed
Search for other papers by Richard A Feelders in
Google Scholar
PubMed
Cornelie D Andela
Cornelie D Andela
Division of Endocrinology and Centre for Endocrine Tumours, Leiden University Medical Centre, Leiden, Netherlands
Search for other papers by Cornelie D Andela in
Google Scholar
PubMed
Search for other papers by Cornelie D Andela in
Google Scholar
PubMed
Margueritta Abou-Hanna
Margueritta Abou-Hanna
HRA Pharma Rare Diseases, Châtillon, France
Search for other papers by Margueritta Abou-Hanna in
Google Scholar
PubMed
Search for other papers by Margueritta Abou-Hanna in
Google Scholar
PubMed
Sarah Idres
Sarah Idres
HRA Pharma Rare Diseases, Châtillon, France
Search for other papers by Sarah Idres in
Google Scholar
PubMed
Search for other papers by Sarah Idres in
Google Scholar
PubMed
Antoine Tabarin
Antoine Tabarin
Department of Endocrinology and INSERM U862 University and CHU of Bordeaux, Pessac, France
Search for other papers by Antoine Tabarin in
Google Scholar
PubMed
Search for other papers by Antoine Tabarin in
Google Scholar
PubMed
depression, the time taken to diagnose CS is often long, resulting in a significant number of patients with persistent sequelae and impairments in QoL ( 6 , 9 ). Given the burden of the disease, ideal CS treatment would include early diagnosis, curative
Rachel Forfar
Rachel Forfar
Centre for Therapeutics Discovery, LifeArc, Accelerator Building, Open Innovation Campus, Stevenage, UK
Search for other papers by Rachel Forfar in
Google Scholar
PubMed
Search for other papers by Rachel Forfar in
Google Scholar
PubMed
Mashal Hussain
Mashal Hussain
Centre for Endocrinology, William Harvey Research Institute, Queen Mary University of London, London, UK
Search for other papers by Mashal Hussain in
Google Scholar
PubMed
Search for other papers by Mashal Hussain in
Google Scholar
PubMed
Puneet Khurana
Puneet Khurana
Centre for Therapeutics Discovery, LifeArc, Accelerator Building, Open Innovation Campus, Stevenage, UK
Search for other papers by Puneet Khurana in
Google Scholar
PubMed
Search for other papers by Puneet Khurana in
Google Scholar
PubMed
Jennifer Cook
Jennifer Cook
Centre for Therapeutics Discovery, LifeArc, Accelerator Building, Open Innovation Campus, Stevenage, UK
Search for other papers by Jennifer Cook in
Google Scholar
PubMed
Search for other papers by Jennifer Cook in
Google Scholar
PubMed
Steve Lewis
Steve Lewis
Centre for Therapeutics Discovery, LifeArc, Accelerator Building, Open Innovation Campus, Stevenage, UK
Search for other papers by Steve Lewis in
Google Scholar
PubMed
Search for other papers by Steve Lewis in
Google Scholar
PubMed
Dillon Popat
Dillon Popat
Centre for Endocrinology, William Harvey Research Institute, Queen Mary University of London, London, UK
Search for other papers by Dillon Popat in
Google Scholar
PubMed
Search for other papers by Dillon Popat in
Google Scholar
PubMed
David Jackson
David Jackson
Centre for Endocrinology, William Harvey Research Institute, Queen Mary University of London, London, UK
Search for other papers by David Jackson in
Google Scholar
PubMed
Search for other papers by David Jackson in
Google Scholar
PubMed
Ed McIver
Ed McIver
Centre for Therapeutics Discovery, LifeArc, Accelerator Building, Open Innovation Campus, Stevenage, UK
Search for other papers by Ed McIver in
Google Scholar
PubMed
Search for other papers by Ed McIver in
Google Scholar
PubMed
Jeff Jerman
Jeff Jerman
Centre for Therapeutics Discovery, LifeArc, Accelerator Building, Open Innovation Campus, Stevenage, UK
Search for other papers by Jeff Jerman in
Google Scholar
PubMed
Search for other papers by Jeff Jerman in
Google Scholar
PubMed
Debra Taylor
Debra Taylor
Centre for Therapeutics Discovery, LifeArc, Accelerator Building, Open Innovation Campus, Stevenage, UK
Search for other papers by Debra Taylor in
Google Scholar
PubMed
Search for other papers by Debra Taylor in
Google Scholar
PubMed
Adrian JL Clark
Adrian JL Clark
Centre for Endocrinology, William Harvey Research Institute, Queen Mary University of London, London, UK
Search for other papers by Adrian JL Clark in
Google Scholar
PubMed
Search for other papers by Adrian JL Clark in
Google Scholar
PubMed
Li F Chan
Li F Chan
Centre for Endocrinology, William Harvey Research Institute, Queen Mary University of London, London, UK
Search for other papers by Li F Chan in
Google Scholar
PubMed
Search for other papers by Li F Chan in
Google Scholar
PubMed
, prostate cancer, obesity, and depression. In conclusion, this study has discovered a small-molecule antagonist of ACTH stimulation of the human and mouse MC2R-MRAP, with high selectivity for human MC2 amongst human melanocortin receptors, and potential
Gregory Knowles
Gregory Knowles
Walsall Manor Hospital, Walsall, UK
Search for other papers by Gregory Knowles in
Google Scholar
PubMed
Search for other papers by Gregory Knowles in
Google Scholar
PubMed
Emily Warmington
Emily Warmington
College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK
Search for other papers by Emily Warmington in
Google Scholar
PubMed
Search for other papers by Emily Warmington in
Google Scholar
PubMed
Lisa M Shepherd
Lisa M Shepherd
Department of Endocrinology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
Search for other papers by Lisa M Shepherd in
Google Scholar
PubMed
Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
Search for other papers by Lisa M Shepherd in
Google Scholar
PubMed
Jonathan M Hazlehurst
Jonathan M Hazlehurst
Department of Endocrinology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
Institute of Applied Health Research, University of Birmingham, Birmingham, UK
Search for other papers by Jonathan M Hazlehurst in
Google Scholar
PubMed
Institute of Applied Health Research, University of Birmingham, Birmingham, UK
Search for other papers by Jonathan M Hazlehurst in
Google Scholar
PubMed
Anne de Bray
Anne de Bray
Department of Endocrinology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
Search for other papers by Anne de Bray in
Google Scholar
PubMed
Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
Search for other papers by Anne de Bray in
Google Scholar
PubMed
Helena Gleeson
Helena Gleeson
Department of Endocrinology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
Search for other papers by Helena Gleeson in
Google Scholar
PubMed
Search for other papers by Helena Gleeson in
Google Scholar
PubMed
Wiebke Arlt
Wiebke Arlt
Department of Endocrinology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
Medical Research Council London Institute of Medical Sciences, London, UK
Search for other papers by Wiebke Arlt in
Google Scholar
PubMed
Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
Medical Research Council London Institute of Medical Sciences, London, UK
Search for other papers by Wiebke Arlt in
Google Scholar
PubMed
Alessandro Prete
Alessandro Prete
Department of Endocrinology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
NIHR Birmingham Biomedical Research Centre, University of Birmingham and University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
Search for other papers by Alessandro Prete in
Google Scholar
PubMed
Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
NIHR Birmingham Biomedical Research Centre, University of Birmingham and University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
Search for other papers by Alessandro Prete in
Google Scholar
PubMed
.999 Sleep apnoea, n (%) 3 (3.7) – 0.246 Depression, n (%) 3 (3.7) 6 (7.5) 0.325 History of cancer, n (%) 2 (2.4) 1 (1.3) >0.999 Candidiasis, n (%) 1 (1.2) – >0.999 Testicular adrenal rest
Susan M Webb
Susan M Webb
IIB-Sant Pau, Research Center for Pituitary Diseases, Barcelona, Spain
Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER, Unidad 747), ISCIII, Spain
Department of Endocrinology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
Department of Medicine, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain
Search for other papers by Susan M Webb in
Google Scholar
PubMed
Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER, Unidad 747), ISCIII, Spain
Department of Endocrinology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
Department of Medicine, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain
Search for other papers by Susan M Webb in
Google Scholar
PubMed
Jette Kristensen
Jette Kristensen
ePAG & Chair of Danish Addison Patient Association, Aarhus, Denmark
Search for other papers by Jette Kristensen in
Google Scholar
PubMed
Search for other papers by Jette Kristensen in
Google Scholar
PubMed
Anna Nordenström
Anna Nordenström
Pediatric Endocrinology, Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden
Search for other papers by Anna Nordenström in
Google Scholar
PubMed
Search for other papers by Anna Nordenström in
Google Scholar
PubMed
Diana Vitali
Diana Vitali
ePAG & Chair SOD ITALIA - Italian Patients Organization for Septo Optic Dysplasia and other Neuroendocrine Conditions, Rome, Italy
Search for other papers by Diana Vitali in
Google Scholar
PubMed
Search for other papers by Diana Vitali in
Google Scholar
PubMed
Vincent Amodru
Vincent Amodru
Aix-Marseille Université, Institut National de la Santé et de la Recherche Médicale (INSERM), U1251, Marseille Medical Genetics, Institut MarMaRa, Marseille, France
Search for other papers by Vincent Amodru in
Google Scholar
PubMed
Search for other papers by Vincent Amodru in
Google Scholar
PubMed
Lenja Katharina Wiehe
Lenja Katharina Wiehe
EURORDIS - Rare Diseases Europe, Paris, France
Search for other papers by Lenja Katharina Wiehe in
Google Scholar
PubMed
Search for other papers by Lenja Katharina Wiehe in
Google Scholar
PubMed
Matt Bolz-Johnson
Matt Bolz-Johnson
EURORDIS - Rare Diseases Europe, Paris, France
Search for other papers by Matt Bolz-Johnson in
Google Scholar
PubMed
Search for other papers by Matt Bolz-Johnson in
Google Scholar
PubMed
, appearance of more body hair, snoring or sleep apnea, weight gain, skin thickening, jaw growth with toothache, high blood pressure Feeling ‘something is wrong’ Psychological: insomnia, lack of concentration, less memory, unreasonable nervousness, depression
Paul-Martin Holterhus
Paul-Martin Holterhus
Department of Pediatrics I, Pediatric Endocrinology and Diabetology, University Hospital of Schleswig-Holstein, UKSH, Campus Kiel and Christian Albrechts University, CAU, Kiel, Germany
Search for other papers by Paul-Martin Holterhus in
Google Scholar
PubMed
Search for other papers by Paul-Martin Holterhus in
Google Scholar
PubMed
Alexandra Kulle
Alexandra Kulle
Department of Pediatrics I, Pediatric Endocrinology and Diabetology, University Hospital of Schleswig-Holstein, UKSH, Campus Kiel and Christian Albrechts University, CAU, Kiel, Germany
Search for other papers by Alexandra Kulle in
Google Scholar
PubMed
Search for other papers by Alexandra Kulle in
Google Scholar
PubMed
Anne-Marie Till
Anne-Marie Till
Department of Pediatrics, Pediatric Hematology and Oncology, University Hospital of Schleswig-Holstein, UKSH, Campus Lübeck, Germany
Search for other papers by Anne-Marie Till in
Google Scholar
PubMed
Search for other papers by Anne-Marie Till in
Google Scholar
PubMed
Caroline Stille
Caroline Stille
Department of Pediatrics, Pediatric Hematology and Oncology, University Hospital of Schleswig-Holstein, UKSH, Campus Lübeck, Germany
Search for other papers by Caroline Stille in
Google Scholar
PubMed
Search for other papers by Caroline Stille in
Google Scholar
PubMed
Tabea Lamprecht
Tabea Lamprecht
Department of Pediatrics I, Pediatric Endocrinology and Diabetology, University Hospital of Schleswig-Holstein, UKSH, Campus Kiel and Christian Albrechts University, CAU, Kiel, Germany
Search for other papers by Tabea Lamprecht in
Google Scholar
PubMed
Search for other papers by Tabea Lamprecht in
Google Scholar
PubMed
Simon Vieth
Simon Vieth
Department of Pediatrics I, Pediatric Hematology and Oncology, University Hospital of Schleswig-Holstein, UKSH, Campus Kiel and Christian-Albrechts-University, CAU, Kiel, Germany
Search for other papers by Simon Vieth in
Google Scholar
PubMed
Search for other papers by Simon Vieth in
Google Scholar
PubMed
Melchior Lauten
Melchior Lauten
Department of Pediatrics, Pediatric Hematology and Oncology, University Hospital of Schleswig-Holstein, UKSH, Campus Lübeck, Germany
Search for other papers by Melchior Lauten in
Google Scholar
PubMed
Search for other papers by Melchior Lauten in
Google Scholar
PubMed
-workers reported dexamethasone-induced suppression of aldosterone in CAH ( 14 ). Holsboer and co-workers reported dexamethasone-induced suppression of DOC and corticosterone in female patients with endogenous depression ( 15 ). The endocrine mechanism underlying
Dafydd Aled Rees
Dafydd Aled Rees
Cardiff University, Cardiff, United Kingdom
Search for other papers by Dafydd Aled Rees in
Google Scholar
PubMed
Search for other papers by Dafydd Aled Rees in
Google Scholar
PubMed
Deborah P Merke
Deborah P Merke
National Institutes of Health Clinical Center and the Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, USA
Search for other papers by Deborah P Merke in
Google Scholar
PubMed
Search for other papers by Deborah P Merke in
Google Scholar
PubMed
Wiebke Arlt
Wiebke Arlt
MRC LMS, London, United Kingdom
Search for other papers by Wiebke Arlt in
Google Scholar
PubMed
Search for other papers by Wiebke Arlt in
Google Scholar
PubMed
Aude Brac De La Perriere
Aude Brac De La Perriere
Hospices Civils de Lyon - GHE - Endocrinologie, Bron, France
Search for other papers by Aude Brac De La Perriere in
Google Scholar
PubMed
Search for other papers by Aude Brac De La Perriere in
Google Scholar
PubMed
Angelica Linden Hirschberg
Angelica Linden Hirschberg
Karolinska Institute, Solna, Sweden
Search for other papers by Angelica Linden Hirschberg in
Google Scholar
PubMed
Search for other papers by Angelica Linden Hirschberg in
Google Scholar
PubMed
Anders Juul
Anders Juul
Department of Growth and Reproduction, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark, and Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
Search for other papers by Anders Juul in
Google Scholar
PubMed
Search for other papers by Anders Juul in
Google Scholar
PubMed
John Newell-Price
John Newell-Price
The University of Sheffield, Sheffield, United Kingdom
Search for other papers by John Newell-Price in
Google Scholar
PubMed
Search for other papers by John Newell-Price in
Google Scholar
PubMed
Alessandro Prete
Alessandro Prete
University of Birmingham, Birmingham, United Kingdom
Search for other papers by Alessandro Prete in
Google Scholar
PubMed
Search for other papers by Alessandro Prete in
Google Scholar
PubMed
Nicole Reisch
Nicole Reisch
Endokrinologie, Nephrologie und weitere Sektionen - Medizinische Klinik und Poliklinik IV - Campus Innenstadt, München, Germany
Search for other papers by Nicole Reisch in
Google Scholar
PubMed
Search for other papers by Nicole Reisch in
Google Scholar
PubMed
Nike M Stikkelbroeck
Nike M Stikkelbroeck
Radboud University Nijmegen, Nijmegen, Netherlands
Search for other papers by Nike M Stikkelbroeck in
Google Scholar
PubMed
Search for other papers by Nike M Stikkelbroeck in
Google Scholar
PubMed
Philippe A Touraine
Philippe A Touraine
University Hospitals Pitié Salpêtrière - Charles Foix, Paris, France
Search for other papers by Philippe A Touraine in
Google Scholar
PubMed
Search for other papers by Philippe A Touraine in
Google Scholar
PubMed
Alex Lewis
Alex Lewis
Neurocrine Biosciences Inc, London, United Kingdom
Search for other papers by Alex Lewis in
Google Scholar
PubMed
Search for other papers by Alex Lewis in
Google Scholar
PubMed
John Porter
John Porter
Neurocrine Biosciences Inc, London, United Kingdom
Search for other papers by John Porter in
Google Scholar
PubMed
Search for other papers by John Porter in
Google Scholar
PubMed
Helen Coope
Helen Coope
Neurocrine Biosciences Inc, London, United Kingdom
Search for other papers by Helen Coope in
Google Scholar
PubMed
Search for other papers by Helen Coope in
Google Scholar
PubMed
Richard J Ross
Richard J Ross
The University of Sheffield, Sheffield, United Kingdom
Search for other papers by Richard J Ross in
Google Scholar
PubMed
Search for other papers by Richard J Ross in
Google Scholar
PubMed
.26310.bd ) 23 Jenkins-Jones S Parviainen L Porter J Withe M Whitaker MJ Holden SE Morgan CL Currie CJ & Ross RJM . Poor compliance and increased mortality, depression and healthcare costs in patients with congenital adrenal
Annelies van’t Westeinde
Annelies van’t Westeinde
Department of Women’s and Children’s Health, Karolinska Institutet and Division of Pediatrics, Unit for Pediatric Endocrinology and Metabolic Disorders, Karolinska University Hospital, Stockholm, Sweden
Search for other papers by Annelies van’t Westeinde in
Google Scholar
PubMed
Search for other papers by Annelies van’t Westeinde in
Google Scholar
PubMed
Leif Karlsson
Leif Karlsson
Department of Women’s and Children’s Health, Karolinska Institutet and Division of Pediatrics, Unit for Pediatric Endocrinology and Metabolic Disorders, Karolinska University Hospital, Stockholm, Sweden
Search for other papers by Leif Karlsson in
Google Scholar
PubMed
Search for other papers by Leif Karlsson in
Google Scholar
PubMed
Valeria Messina
Valeria Messina
Department of Women’s and Children’s Health, Karolinska Institutet and Division of Pediatrics, Unit for Pediatric Endocrinology and Metabolic Disorders, Karolinska University Hospital, Stockholm, Sweden
Search for other papers by Valeria Messina in
Google Scholar
PubMed
Search for other papers by Valeria Messina in
Google Scholar
PubMed
Lena Wallensteen
Lena Wallensteen
Department of Women’s and Children’s Health, Karolinska Institutet and Division of Pediatrics, Unit for Pediatric Endocrinology and Metabolic Disorders, Karolinska University Hospital, Stockholm, Sweden
Search for other papers by Lena Wallensteen in
Google Scholar
PubMed
Search for other papers by Lena Wallensteen in
Google Scholar
PubMed
Manuela Brösamle
Manuela Brösamle
European Patient Advocacy Group for Adrenal Diseases, European Reference Network on Rare Endocrine Conditions (Endo ERN), Endo ERN Coordinating Centre, Leiden, The Netherlands
Search for other papers by Manuela Brösamle in
Google Scholar
PubMed
Search for other papers by Manuela Brösamle in
Google Scholar
PubMed
Giorgio Dal Maso
Giorgio Dal Maso
ArfSAG (Associazione Refionale Famiglie Sindrome Adreno Genitale) c/o Unita Operativa di Pediatria, Azienda Ospedaliero Universitaria di Bologna, Policlinico S Orsala-Malpighi, Bologna, Italy
Search for other papers by Giorgio Dal Maso in
Google Scholar
PubMed
Search for other papers by Giorgio Dal Maso in
Google Scholar
PubMed
Alessandro Lazzerini
Alessandro Lazzerini
Spanish Association of Congenital Adrenal Hyperplasia (CAH), Spain
Search for other papers by Alessandro Lazzerini in
Google Scholar
PubMed
Search for other papers by Alessandro Lazzerini in
Google Scholar
PubMed
Jette Kristensen
Jette Kristensen
ePAG & Chair of Danish Addison Patient Association, Aarhus, Denmark
Search for other papers by Jette Kristensen in
Google Scholar
PubMed
Search for other papers by Jette Kristensen in
Google Scholar
PubMed
Diana Kwast
Diana Kwast
Dutch Adrenal Society NVACP, Nijkerk, The Netherlands
Search for other papers by Diana Kwast in
Google Scholar
PubMed
Search for other papers by Diana Kwast in
Google Scholar
PubMed
Lea Tschaidse
Lea Tschaidse
Department of Endocrinology, Medizinische Klinik IV, Klinikum der Universität München, Munich, Germany
Search for other papers by Lea Tschaidse in
Google Scholar
PubMed
Search for other papers by Lea Tschaidse in
Google Scholar
PubMed
Matthias K Auer
Matthias K Auer
Department of Endocrinology, Medizinische Klinik IV, Klinikum der Universität München, Munich, Germany
Search for other papers by Matthias K Auer in
Google Scholar
PubMed
Search for other papers by Matthias K Auer in
Google Scholar
PubMed
Hanna F Nowotny
Hanna F Nowotny
Department of Endocrinology, Medizinische Klinik IV, Klinikum der Universität München, Munich, Germany
Search for other papers by Hanna F Nowotny in
Google Scholar
PubMed
Search for other papers by Hanna F Nowotny in
Google Scholar
PubMed
Luca Persani
Luca Persani
Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy
Search for other papers by Luca Persani in
Google Scholar
PubMed
Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy
Search for other papers by Luca Persani in
Google Scholar
PubMed
Nicole Reisch
Nicole Reisch
Department of Endocrinology, Medizinische Klinik IV, Klinikum der Universität München, Munich, Germany
Search for other papers by Nicole Reisch in
Google Scholar
PubMed
Search for other papers by Nicole Reisch in
Google Scholar
PubMed
Svetlana Lajic
Svetlana Lajic
Department of Women’s and Children’s Health, Karolinska Institutet and Division of Pediatrics, Unit for Pediatric Endocrinology and Metabolic Disorders, Karolinska University Hospital, Stockholm, Sweden
Search for other papers by Svetlana Lajic in
Google Scholar
PubMed
Search for other papers by Svetlana Lajic in
Google Scholar
PubMed
with DEX have increased ACTH and cortisol levels, altered HPA axis activity ( 52 , 64 ) and also displayed changes in stress-related behaviour such as increased anxiety and depression, in particular in females ( 65 ). In humans, specifically, neonates
Riccardo Pofi
Riccardo Pofi
Department of Endocrinology, Oxford Centre for Diabetes, Endocrinology and Metabolism and NIHR Oxford Biomedical Research Centre, Churchill Hospital, University of Oxford, Oxford, UK
Search for other papers by Riccardo Pofi in
Google Scholar
PubMed
Search for other papers by Riccardo Pofi in
Google Scholar
PubMed
Ilaria Bonaventura
Ilaria Bonaventura
Department of Experimental Medicine, Sapienza University of Rome, Viale Regina Elena, Rome, Italy
Search for other papers by Ilaria Bonaventura in
Google Scholar
PubMed
Search for other papers by Ilaria Bonaventura in
Google Scholar
PubMed
Joanne Duffy
Joanne Duffy
Department of Clinical Chemistry and Immunology, Heartlands Hospital, Birmingham, UK
Search for other papers by Joanne Duffy in
Google Scholar
PubMed
Search for other papers by Joanne Duffy in
Google Scholar
PubMed
Zoe Maunsell
Zoe Maunsell
Department of Clinical Biochemistry, Oxford University Hospitals NHS Foundation Trust, Oxford, UK
Search for other papers by Zoe Maunsell in
Google Scholar
PubMed
Search for other papers by Zoe Maunsell in
Google Scholar
PubMed
Brian Shine
Brian Shine
Department of Clinical Biochemistry, Oxford University Hospitals NHS Foundation Trust, Oxford, UK
Search for other papers by Brian Shine in
Google Scholar
PubMed
Search for other papers by Brian Shine in
Google Scholar
PubMed
Andrea M Isidori
Andrea M Isidori
Department of Experimental Medicine, Sapienza University of Rome, Viale Regina Elena, Rome, Italy
Search for other papers by Andrea M Isidori in
Google Scholar
PubMed
Search for other papers by Andrea M Isidori in
Google Scholar
PubMed
Jeremy W Tomlinson
Jeremy W Tomlinson
Department of Endocrinology, Oxford Centre for Diabetes, Endocrinology and Metabolism and NIHR Oxford Biomedical Research Centre, Churchill Hospital, University of Oxford, Oxford, UK
Search for other papers by Jeremy W Tomlinson in
Google Scholar
PubMed
Search for other papers by Jeremy W Tomlinson in
Google Scholar
PubMed
.1186/1472-6963-12-270 ) 51 Jenkins-Jones S Parviainen L Porter J Withe M Whitaker MJ Holden SE Morgan CL Currie CJ & Ross RJM . Poor compliance and increased mortality, depression and healthcare costs in patients with congenital adrenal hyperplasia
Sharmin Jahan
Sharmin Jahan
Department of Medicine, Monash University, Melbourne, Victoria, Australia
Centre for Endocrinology and Metabolism, Hudson Institute of Medical Research, Victoria, Australia
Department of Endocrinology and Metabolism, BSMMU, Dhaka, Bangladesh
Search for other papers by Sharmin Jahan in
Google Scholar
PubMed
Centre for Endocrinology and Metabolism, Hudson Institute of Medical Research, Victoria, Australia
Department of Endocrinology and Metabolism, BSMMU, Dhaka, Bangladesh
Search for other papers by Sharmin Jahan in
Google Scholar
PubMed
Jun Yang
Jun Yang
Department of Medicine, Monash University, Melbourne, Victoria, Australia
Centre for Endocrinology and Metabolism, Hudson Institute of Medical Research, Victoria, Australia
Search for other papers by Jun Yang in
Google Scholar
PubMed
Centre for Endocrinology and Metabolism, Hudson Institute of Medical Research, Victoria, Australia
Search for other papers by Jun Yang in
Google Scholar
PubMed
Jinbo Hu
Jinbo Hu
Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China
Search for other papers by Jinbo Hu in
Google Scholar
PubMed
Search for other papers by Jinbo Hu in
Google Scholar
PubMed
Qifu Li
Qifu Li
Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China
Search for other papers by Qifu Li in
Google Scholar
PubMed
Search for other papers by Qifu Li in
Google Scholar
PubMed
Peter J Fuller
Peter J Fuller
Centre for Endocrinology and Metabolism, Hudson Institute of Medical Research, Victoria, Australia
Search for other papers by Peter J Fuller in
Google Scholar
PubMed
Search for other papers by Peter J Fuller in
Google Scholar
PubMed
). Patients with PA also display an increased prevalence of metabolic syndrome and diabetes ( 6 , 7 ), osteoporotic fractures ( 8 ), and symptoms of depression with a reduced quality of life ( 9 ). When PA goes undetected, patients miss out on targeted
Deirdre Green
Deirdre Green
Academic Department of Endocrinology, Beaumont Hospital and the Royal College of Surgeons in Ireland, Dublin
Search for other papers by Deirdre Green in
Google Scholar
PubMed
Search for other papers by Deirdre Green in
Google Scholar
PubMed
Rosemary Dineen
Rosemary Dineen
Academic Department of Endocrinology, Beaumont Hospital and the Royal College of Surgeons in Ireland, Dublin
Search for other papers by Rosemary Dineen in
Google Scholar
PubMed
Search for other papers by Rosemary Dineen in
Google Scholar
PubMed
Michael W O’Reilly
Michael W O’Reilly
Academic Department of Endocrinology, Beaumont Hospital and the Royal College of Surgeons in Ireland, Dublin
Search for other papers by Michael W O’Reilly in
Google Scholar
PubMed
Search for other papers by Michael W O’Reilly in
Google Scholar
PubMed
Mark Sherlock
Mark Sherlock
Academic Department of Endocrinology, Beaumont Hospital and the Royal College of Surgeons in Ireland, Dublin
Search for other papers by Mark Sherlock in
Google Scholar
PubMed
Search for other papers by Mark Sherlock in
Google Scholar
PubMed
associated with stress, depression, over exercise and eating disorders. Patients with undiagnosed ACTH deficiency may present with subfertility, with introduction of glucocorticoid therapy resuming an ovulatory menstrual cycle ( 96 , 97 ). Overall, the
