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Department of Pediatrics, Aarhus University Hospital, Aarhus, Denmark
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Steno Diabetes Center Aarhus (SDCA), Aarhus University Hospital, Aarhus, Denmark
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assays preclude its use ( 4 ). Copeptin, which is a split product of the vasopressin pre-pro-peptide, is cleaved and stored with AVP in equimolar amounts in neurosecretory granules in the posterior pituitary gland. Circulating copeptin levels change in
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National Center for Neurological Disorders, Shanghai, China
Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China
Neurosurgical Institute of Fudan University, Shanghai, China
Shanghai Key Laboratory of Medical Brain Function and Restoration and Neural Regeneration, Fudan University, Shanghai, China
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National Center for Neurological Disorders, Shanghai, China
Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China
Neurosurgical Institute of Fudan University, Shanghai, China
Shanghai Key Laboratory of Medical Brain Function and Restoration and Neural Regeneration, Fudan University, Shanghai, China
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). Several limitations exist in this study. First, patients less than 18 years old was excluded. Moreover, the constructed model was not validated using an external database, compromising its clinical generalization. Second, the role of copeptin assays is
Department of Neurosurgery, 900TH Hospital of the Joint Logistics Support Force, Fuzhou, Fujian, China
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://doi.org/10.3171/2013.11.JNS131320 ) 19 Morgenthaler NG Struck J Jochberger S Dünser MW . Copeptin: clinical use of a new biomarker . Trends in Endocrinology and Metabolism 2008 19 43 – 49 . ( https://doi.org/10.1016/j.tem.2007.11.001 ) 20