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Tingting Xia, Hongru Sun, Hao Huang, Haoran Bi, Rui Pu, Lei Zhang, Yuanyuan Zhang, Ying Liu, Jing Xu, Justina Ucheojor Onwuka, Yupeng Liu, Binbin Cui and Yashuang Zhao

Introduction Worldwide, colorectal cancer (CRC) remains among the top three prevalent tumors among women and men according to Global Cancer Statistics with an estimated 1.4 million new cases and 693,900 deaths occurring in 2012 ( 1

Open access

Jordyn Silverstein, Wesley Kidder, Susan Fisher, Thomas A Hope, Samantha Maisel, Dianna Ng, Jessica Van Ziffle, Chloe E Atreya and Katherine Van Loon

States, colorectal cancer (CRC) is the third most common cause of cancer-related death ( 1 ). Over the past two decades, CRC incidence has declined by 3–4% each year ( 2 ). Consistent with CRC screening patterns ( 3 ), this decrease in CRC incidence is

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Katherine A Bolton, Kelly A Avery-Kiejda, Elizabeth G Holliday, John Attia, Nikola A Bowden and Rodney J Scott

are associated with an increased risk of developing breast cancer, as well as prostate, colorectal and lung cancers ( 15 , 18 , 19 , 20 ). Also, mammographic density, which is a strong predictor of breast cancer risk, has been correlated with plasma

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Yuan Fang, Xuehong Zhang, Huilin Xu, Stephanie A Smith-Warner, Dongli Xu, Hong Fang and Wang Hong Xu

Introduction Type 2 diabetes (T2DM) has been associated with an elevated risk of liver, pancreas, endometrium, colorectal, breast and bladder cancers and a decreased risk of prostate cancer ( 1 , 2 ). Several possible mechanisms have been

Open access

Jakob Kirkegård, Dora Körmendiné Farkas, Jens Otto Lunde Jørgensen and Deirdre P Cronin-Fenton

262 individuals, more cases of hyperthyroidism were observed among esophageal cancer cases compared with their controls ( 6 ). In addition, T4 substitution therapy has been correlated with a decreased risk of colorectal cancer ( 7 ). Thus, the

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Corina Verónica Sasso, Flavia Eliana Santiano, Fiorella Campo Verde Arboccó, Leila Ester Zyla, Silvana Noemí Semino, Martin Eduardo Guerrero-Gimenez, Virginia Pistone Creydt, Constanza Matilde López Fontana and Rubén Walter Carón

Introduction Colorectal cancer (CRC) is the third most common cancer and one of the tumors with the highest incidence and mortality worldwide, with an increasing projection for the coming decades. CRC incidence and mortality rates are 30 and

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Renea A Taylor, Jennifer Lo, Natasha Ascui and Matthew J Watt

–2011 data) (1) . This is in contrast to other more aggressive cancers that have significantly lower 5-year survival rates (e.g., 17.4 and 64.9% in lung and colorectal cancer respectively) (1) . Consequently, there are many men who live with prostate cancer

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Zhen-yu Song, Qiuming Yao, Zhiyuan Zhuo, Zhe Ma and Gang Chen

.11.7782 ) 5 Diaz GD Paraskeva C Thomas MG Binderup L Hague A. Apoptosis is induced by the active metabolite of vitamin D3 and its analogue EB1089 in colorectal adenoma and carcinoma cells: possible implications for prevention and therapy . Cancer Research

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Ishita Gupta, Allal Ouhtit, Adil Al-Ajmi, Syed Gauhar A Rizvi, Hamad Al-Riyami, Marwa Al-Riyami and Yahya Tamimi

). Our data are similar to those reported on colorectal cancer, where BRIP1 overexpression correlated with poor recurrence-free survival ( 40 ). Also, elevated expression of BRIP1 was observed in high-grade breast tumors correlated with an unfavorable

Open access

Erika Urbano Lima, Ileana G S Rubio, Joaquim Custodio Da Silva, Ana Luiza Galrão, Danielle Pêssoa, Taise Cerqueira Oliveira, Fabiane Carrijo, Igor Silva Campos, Luciano Fonseca Espinheira, Luiz Jose Sampaio, Claudio Rogerio Lima, Janete Maria Cerutti and Helton Estrela Ramos

.2) promoter harbors CpG islands including the first exon and intron ( 13 ). Its epigenetic control has been correlated with tumorigenesis and worse prognosis in uterine, breast, esophageal, gastric, pancreatic and colorectal cancers ( 10 , 11 , 12 , 13