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Faculty of Medicine, University of Belgrade, Belgrade, Serbia
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Faculty of Medicine, University of Belgrade, Belgrade, Serbia
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Institute of Medical Statistics and Informatics, Belgrade, Serbia
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University Children’s Clinic, Belgrade, Serbia
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University Children’s Clinic, Belgrade, Serbia
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Mother and Child Health Care Institute of Serbia ‘Dr Vukan Cupic’, Belgrade, Serbia
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Mother and Child Health Care Institute of Serbia ‘Dr Vukan Cupic’, Belgrade, Serbia
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Faculty of Medicine, University of Belgrade, Belgrade, Serbia
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Clinic for Neurosurgery, University Clinical Center of Serbia, Belgrade, Serbia
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Faculty of Medicine, University of Belgrade, Belgrade, Serbia
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Institute of Pathology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia
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Clinic for Neurosurgery, University Clinical Center of Serbia, Belgrade, Serbia
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Faculty of Medicine, University of Belgrade, Belgrade, Serbia
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Introduction Patients with childhood-onset GH deficiency (COGHD) represent a heterogeneous group in terms of etiology of growth hormone deficiency (GHD), time of GHD onset and recombinant human GH (rhGH) replacement commencement, duration
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Section of Biostatistics, Department of Public Health, University of Copenhagen, Copenhagen, Denmark
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, and a comprehensive internal validation was conducted for every change in assays to standardize the analyses. Reference material Hormone levels during childhood and puberty were compared to a prospectively followed reference cohort of 112 boys
Department of Pediatrics, China-Japan Friendship Hospital, Beijing, China
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Department of Pediatrics, China-Japan Friendship Hospital, Beijing, China
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Department of Pediatrics, China-Japan Friendship Hospital, Beijing, China
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Department of Pediatrics, China-Japan Friendship Hospital, Beijing, China
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Department of Pediatrics, China-Japan Friendship Hospital, Beijing, China
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special attention due to its underlying physical and psychosocial impairments from childhood to adulthood, such as cardiometabolic diseases, diabetes and psychological functioning problems ( 6 , 7 , 8 , 9 ). In clinical practice, pre-shortness is often
AP-HP.Nord-Université de Paris, Hôpital Universitaire Robert Debré, Unité d’Épidémiologie Clinique, Inserm, Paris, France
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Green A Soltész G EURODIAB Study Group. Incidence trends for childhood type 1 diabetes in Europe during 1989–2003 and predicted new cases 2005–20: a multicentre prospective registration study . Lancet 2009 373 2027 – 20 33 . ( https
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Introduction Calcium (Ca) is the primary nutrient of interest in bone health. It is essential to ensure adequate Ca intake to support the accelerated growth spurt during childhood and adolescence when bone accumulates and grows at a rapid rate
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Dipartimento di Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno-infantili, Università di Genova, Genova, Italy
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Dipartimento di Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno-infantili, Università di Genova, Genova, Italy
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Dipartimento di Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno-infantili, Università di Genova, Genova, Italy
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Introduction The diagnosis of growth hormone deficiency (GHD) in childhood and adolescence is based on auxological, biochemical, neuro-radiological, and genetic investigations. Since GH production is pulsatile, its secretion needs to be
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Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK
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differences ( 5 , 6 , 7 , 8 , 9 , 10 ). Sexual dimorphism in HPA-axis activity has been suggested to be already present in early childhood. A recent meta-analysis suggested that boys and girls differed in basal HPA-axis activity, as assessed by salivary
Department of Pediatrics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Reproduction & Development Research Institute, de Boelelaan, Amsterdam, The Netherlands
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Department of Pediatrics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Reproduction & Development Research Institute, de Boelelaan, Amsterdam, The Netherlands
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Department of Pediatrics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Reproduction & Development Research Institute, de Boelelaan, Amsterdam, The Netherlands
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), late-onset sepsis (LOS), bronchopulmonary dysplasia (BPD) and intraventricular hemorrhage (IVH), and more often require invasive respiratory support ( 2 , 4 , 5 ), than females. In childhood, male preterm infants had a greater odds of (major and minor
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.ghir.2008.08.001 ) 18 Marshall WA Tanner JM . Variations in pattern of pubertal changes in girls . Archives of Disease in Childhood 1969 44 291 – 303 . ( https://doi.org/10.1136/adc.44.235.291 ) 19 Marshall WA Tanner JM . Variations in
Department of Molecular Endocrinology, National Research Institute for Child Health and Development, Setagaya, Tokyo, Japan
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Department of Molecular Endocrinology, National Research Institute for Child Health and Development, Setagaya, Tokyo, Japan
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Research Center for Environment and Developmental Medical Sciences, Kyushu University, Higashi-ku, Fukuoka, Japan
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Research Center for Environment and Developmental Medical Sciences, Kyushu University, Higashi-ku, Fukuoka, Japan
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Department of Molecular Endocrinology, National Research Institute for Child Health and Development, Setagaya, Tokyo, Japan
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. Further studies are necessary to clarify whether sex hormone production in childhood is associated with sexual maturation during puberty or reproductive function in adulthood. In conclusion, the results show that sexual dimorphism in sex hormone