Qiankai Jin
Qiankai Jin
Department of Endocrinology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, China
School of Medicine, Ningbo University, Ningbo, China
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School of Medicine, Ningbo University, Ningbo, China
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Guoqing Huang
Guoqing Huang
Department of Endocrinology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, China
School of Medicine, Ningbo University, Ningbo, China
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School of Medicine, Ningbo University, Ningbo, China
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Xiaoqing Tian
Xiaoqing Tian
Department of Endocrinology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, China
School of Medicine, Ningbo University, Ningbo, China
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School of Medicine, Ningbo University, Ningbo, China
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Yimeng Shu
Yimeng Shu
Department of Endocrinology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, China
School of Medicine, Ningbo University, Ningbo, China
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School of Medicine, Ningbo University, Ningbo, China
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Ximisinuer Tusongtuoheti
Ximisinuer Tusongtuoheti
Department of Endocrinology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, China
School of Medicine, Ningbo University, Ningbo, China
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School of Medicine, Ningbo University, Ningbo, China
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Yushan Mao
Yushan Mao
Department of Endocrinology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, China
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Introduction Metabolic syndrome (MetS) is defined as a cluster of cardiovascular risk factors that occur together in individuals ( 1 ). It is diagnosed when the individual has three or more of its components (central obesity, hypertension
Maria Luisa Garo
Maria Luisa Garo
Mathsly Research, Roma, Italy
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Désirée Deandreis
Désirée Deandreis
Division of Nuclear Medicine, Department of Medical Sciences, AOU Città della Salute e della Scienza, University of Turin, Turin, Italy
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Alfredo Campennì
Alfredo Campennì
Nuclear Medicine Unit, Department of Biomedical and Dental Sciences and Morpho-Functional Imaging, University of Messina, Messina, Italy
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Alexis Vrachimis
Alexis Vrachimis
Department of Nuclear Medicine, German Oncology Center, University Hospital of the European University, Limassol, Cyprus
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Petra Petranovic Ovcaricek
Petra Petranovic Ovcaricek
Department of Oncology and Nuclear Medicine, University Hospital Center Sestre Milosrdnice, Zagreb, Croatia
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Luca Giovanella
Luca Giovanella
Clinic for Nuclear Medicine and Molecular Imaging, Imaging Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland
Clinic for Nuclear Medicine, University Hospital of Zürich, Zürich, Switzerland
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Clinic for Nuclear Medicine, University Hospital of Zürich, Zürich, Switzerland
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prognosis, and a 10-year survival rate of more than 90% ( 11 , 12 , 13 ). Nevertheless, the risk of recurrence ranges from 5 to 21% ( 14 , 15 ), with a prevalence of lymph node metastases of approximately 30–90%, occurring mainly in the central neck
Qing Zhou
Qing Zhou
Department of Endocrinology, Fujian Maternity and Child Health Hospital, Fujian Children’s Hospital, Fuzhou, China
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Li Yong Zhang
Li Yong Zhang
Department of Thyroid Surgery, Minimal Invasive Center, Fujian Medical University Union Hospital, Fuzhou, China
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Mei Feng Dai
Mei Feng Dai
Department of Clinical Lab, Fujian Maternity and Child Health Hospital, Fuzhou, China
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Zhen Li
Zhen Li
Department of Endocrinology, Fujian Maternity and Child Health Hospital, Fujian Children’s Hospital, Fuzhou, China
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Chao Chun Zou
Chao Chun Zou
Department of Endocrinology, The Children’s Hospital, Zhejiang University School of Medicine, Hangzhou, China
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Hui Liu
Hui Liu
Department of Endocrinology, Fujian Maternity and Child Health Hospital, Fujian Children’s Hospital, Fuzhou, China
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Karin M & Hotamisligil GS . A central role for JNK in obesity and insulin resistance . Nature 2002 420 333 – 336 . ( https://doi.org/10.1038/nature01137 )
Bjarke R Medici
Bjarke R Medici
Department of Medicine, Herlev Hospital, University of Copenhagen, Herlev, Denmark
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
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Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
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Birte Nygaard
Birte Nygaard
Department of Medicine, Herlev Hospital, University of Copenhagen, Herlev, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Jeppe L la Cour
Jeppe L la Cour
Department of Medicine, Herlev Hospital, University of Copenhagen, Herlev, Denmark
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Martin Krakauer
Martin Krakauer
Department of Clinical Physiology and Nuclear Medicine, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Department of Clinical Physiology and Nuclear Medicine, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Physiology and Nuclear Medicine, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark
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Andreas Brønden
Andreas Brønden
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Department of Clinical Pharmacology, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Pharmacology, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark
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Mette P Sonne
Mette P Sonne
Department of Medicine, Herlev Hospital, University of Copenhagen, Herlev, Denmark
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Jens J Holst
Jens J Holst
Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Jens F Rehfeld
Jens F Rehfeld
Department of Clinical Biochemistry, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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Tina Vilsbøll
Tina Vilsbøll
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Steno Diabetes Center Copenhagen, Herlev, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Steno Diabetes Center Copenhagen, Herlev, Denmark
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Jens Faber
Jens Faber
Department of Medicine, Herlev Hospital, University of Copenhagen, Herlev, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Filip K Knop
Filip K Knop
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Steno Diabetes Center Copenhagen, Herlev, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Steno Diabetes Center Copenhagen, Herlev, Denmark
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that hypothyroidism leads to overweight/obesity, studies point to a similar body composition between hypothyroid individuals and healthy controls ( 9 , 10 ). When initiating levothyroxine therapy, people are often told to anticipate improvements in
Hanneke J C M Wouters
Hanneke J C M Wouters
Department of Endocrinology, University of Groningen, University Medical Center Groningen, The Netherlands
Department of Hematology, University of Groningen, University Medical Center Groningen, The Netherlands
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Department of Hematology, University of Groningen, University Medical Center Groningen, The Netherlands
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Bruce H R Wolffenbuttel
Bruce H R Wolffenbuttel
Department of Endocrinology, University of Groningen, University Medical Center Groningen, The Netherlands
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Anneke C Muller Kobold
Anneke C Muller Kobold
Department of Laboratory Medicine, University of Groningen, University Medical Center Groningen, The Netherlands
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Thera P Links
Thera P Links
Department of Endocrinology, University of Groningen, University Medical Center Groningen, The Netherlands
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Gerwin Huls
Gerwin Huls
Department of Hematology, University of Groningen, University Medical Center Groningen, The Netherlands
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Melanie M van der Klauw
Melanie M van der Klauw
Department of Endocrinology, University of Groningen, University Medical Center Groningen, The Netherlands
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, part of the samples was directly transferred to the central laboratory of the University Medical Center Groningen, to perform routine clinical chemistry assays on fresh samples. The remaining samples were stored at −80°C and are available for future
Shi-en Fu
Shi-en Fu
Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Rou-mei Wang
Rou-mei Wang
Department of Ultrasonic Diagnosis, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Xing-huan Liang
Xing-huan Liang
Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Jing Xian
Jing Xian
Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Jie Pan
Jie Pan
Department of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Xue-lan Chen
Xue-lan Chen
Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Cheng-cheng Qiu
Cheng-cheng Qiu
Department of Ultrasonic Diagnosis, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Zhi-ping Tang
Zhi-ping Tang
Department of Ultrasonic Diagnosis, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Ying-fen Qin
Ying-fen Qin
Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Hai-yan Yang
Hai-yan Yang
Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Li-li Huang
Li-li Huang
Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
Department of Endocrinology, The Affiliated Hospital of Guilin Medical University, Guilin, China
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Department of Endocrinology, The Affiliated Hospital of Guilin Medical University, Guilin, China
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Ya-qi Kuang
Ya-qi Kuang
Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Yan Ma
Yan Ma
Department of Ultrasonic Diagnosis, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Zuo-jie Luo
Zuo-jie Luo
Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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CTM, electromyography data were collected to test for myogenic damage to assist in the diagnosis of CTM ( 28 ). Myasthenia gravis, thyrotoxic periodic paralysis, central nervous system disorders, and other reasons for progressive muscular weakness
Sophie-Charlotte Drogge
Sophie-Charlotte Drogge
Institute of Medical Informatics, Biometry and Epidemiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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Mirjam Frank
Mirjam Frank
Institute of Medical Informatics, Biometry and Epidemiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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Carolin Girschik
Carolin Girschik
Institute of Medical Informatics, Biometry and Epidemiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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Karl-Heinz Jöckel
Karl-Heinz Jöckel
Institute of Medical Informatics, Biometry and Epidemiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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Dagmar Führer-Sakel
Dagmar Führer-Sakel
Department of Endocrinology, Diabetes and Metabolism, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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Börge Schmidt
Börge Schmidt
Institute of Medical Informatics, Biometry and Epidemiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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of developing hypothyroidism, while obesity may be a risk factor for hypothyroidism ( 14 ). There are indications that people in high SEP groups are more physically active in their leisure time, while obesity is more frequent in people with low SEP
Xiaoyi Qi
Xiaoyi Qi
Departments of Cardiology, Peking University Shenzhen Hospital, Shenzhen, China
Medical College, Shantou University, Shantou, China
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Medical College, Shantou University, Shantou, China
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Liangxian Qiu
Liangxian Qiu
Departments of Cardiology, Peking University Shenzhen Hospital, Shenzhen, China
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Shijia Wang
Shijia Wang
Departments of Cardiology, Peking University Shenzhen Hospital, Shenzhen, China
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Xiongbiao Chen
Xiongbiao Chen
Departments of Cardiology, Peking University Shenzhen Hospital, Shenzhen, China
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Qianwen Huang
Qianwen Huang
Departments of Cardiology, Peking University Shenzhen Hospital, Shenzhen, China
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Yixuan Zhao
Yixuan Zhao
Departments of Cardiology, Peking University Shenzhen Hospital, Shenzhen, China
Medical College, Shantou University, Shantou, China
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Medical College, Shantou University, Shantou, China
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Kunfu Ouyang
Kunfu Ouyang
Department of Cardiovascular Surgery, Peking University Shenzhen Hospital, School of Chemical Biology and Biotechnology, State Key Laboratory of Chemical Oncogenomics, Peking University Shenzhen Graduate School, Shenzhen, China
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Yanjun Chen
Yanjun Chen
Departments of Cardiology, Peking University Shenzhen Hospital, Shenzhen, China
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conclusions. Thyroid hormone (TH) plays a central role in regulating the cardiovascular system. Thyroxine is converted to the biologically active form of TH, triiodothyronine (T 3 ), by the deiodinase enzyme ( 13 ). By binding to the nuclear receptor, T 3
