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-sectional 336 F/M 35–65 Middle-aged overweight and obese healthy adults Radioimmunoassays – Weight, height, BMI, WC, HC, body composition. Age, sex, race, season, supplement use, PTH Total and central adiposity but not peripheral adiposity
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Center for Biochemistry, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany
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Center for Biochemistry, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany
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Center for Biochemistry, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany
Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany
Cologne Center for Musculoskeletal Biomechanics (CCMB), Cologne, Germany
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hypothalamus, where it stimulates appetite-modulating neurons in the arcuate ( 2 ). Clinical studies showed that circulating asprosin levels positively correlated with obesity and type 2 diabetes ( 3 , 4 ). Pre-clinical studies addressing the therapeutic
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muscle to insulin, defined as insulin resistance (IR), contribute to the development of obesity, type 2 diabetes mellitus (T2DM), and cardiovascular diseases. Skeletal muscle insulin action is decreased in prediabetes and T2DM, but it also may be largely
PhyMedExp, Université de Montpellier, INSERM, CNRS, Montpellier, France
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PhyMedExp, Université de Montpellier, INSERM, CNRS, Montpellier, France
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CIC INSERM 1411, Hôpital Gui de Chauliac, CHU Montpellier, Montpellier Cedex 5, France
Institut de Génomique Fonctionnelle, CNRS UMR 5203/INSERM U661/Université Montpellier, Montpellier, France
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CIC INSERM 1411, Hôpital Gui de Chauliac, CHU Montpellier, Montpellier Cedex 5, France
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Département de Biochimie, Hôpital Lapeyronie, CHU Montpellier, Montpellier, France
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Département d’Urgence et Post-Urgence Psychiatrique, Hôpital Lapeyronie, CHU Montpellier, Montpellier, France
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Département d’Urgence et Post-Urgence Psychiatrique, Hôpital Lapeyronie, CHU Montpellier, Montpellier, France
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Département Endocrinologie, Nutrition, Diabète, Equipe Nutrition, Diabète, CHU Montpellier, Montpellier, France
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and students in the Departments of Nuclear Medicine, Endocrinology and Psychiatry of Lapeyronie Hospital, Montpellier University Hospital Centre. The group composed of 42 non-obese healthy adolescents and young women with 18 < BMI < 30 kg/m 2 and no
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Paediatric Neurosciences Research Group, Royal Hospital for Children, NHS Greater Glasgow & Clyde, Glasgow, UK
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marrow inhomogeneity and a visual qualitative assessment for participant motion and image artefacts was also performed by two observers. The analysis was performed to obtain trabecular measures from the central slice (slice 10) from 20 slices per
School of Nursing, Institute of Clinical Sciences, University of Birmingham, Edgbaston, Birmingham, UK
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serum 25D status with immune dysregulation, notably autoimmune disease. Table 1 summarises the various reports that have assessed the impact of 25D status on specific autoimmune diseases. The central conclusion from these studies is that low serum 25D
Fondazione Italiana Ricerca sulle Malattie dell’Osso (FIRMO Onlus), Florence, Italy
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InCHIANTI Biobank, at the Piero Palagi Hospital. For BPA assays, urine samples were collected and stored at −80°C until further use. Laboratory assays Assays for all variables were performed at our central laboratory, Azienda Ospedaliero