M Cherenko
M Cherenko
Department of Medicine, Division of Endocrinology, Leiden University Medical Centre, Leiden, Netherlands
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N M Appelman-Dijkstra
N M Appelman-Dijkstra
Department of Medicine, Division of Endocrinology, Leiden University Medical Centre, Leiden, Netherlands
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A L Priego Zurita
A L Priego Zurita
Department of Medicine, Division of Endocrinology, Leiden University Medical Centre, Leiden, Netherlands
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N R Biermasz
N R Biermasz
Department of Medicine, Division of Endocrinology, Leiden University Medical Centre, Leiden, Netherlands
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O M Dekkers
O M Dekkers
Department of Medicine, Division of Endocrinology, Leiden University Medical Centre, Leiden, Netherlands
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F A Klok
F A Klok
Department of Medicine, Division of Thrombosis and Haemostasis, Leiden University Medical Centre, Leiden, Netherlands
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N Reisch
N Reisch
Department of Medicine IV, LMU University Hospital, LMU Munich, Munich, Germany
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A Aulinas
A Aulinas
Department of Endocrinology, Fundacio de Gestio Sanitaria Hospital de la Santa Creu i Sant Pau, IR-SantPau and CIBERER Unit 747 (ISCIII), Barcelona, Spain
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B Biagetti
B Biagetti
Department of Endocrinology, Hospital Universitari Vall d’Hebron, Barcelona, Spain
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S Cannavo
S Cannavo
Endocrine Unit, University Hospital AOU Policlinico G. Martino, Messina, Italy
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L Canu
L Canu
University Hospital Florence Careggi, Florence, Italy
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M Detomas
M Detomas
Department of Internal Medicine, University Hospital Würzburg, Wuerzburg, Germany
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F Devuyst
F Devuyst
Department of Endocrinology, Hôpital Universitaire de Bruxelles, Hôpital Erasme, Brussels, Belgium
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H Falhammar
H Falhammar
Department of Endocrinology, Karolinska University Hospital and Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
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R A Feelders
R A Feelders
Department of Internal Medicine, Division of Endocrinology, Erasmus MC, Rotterdam, Netherlands
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F Ferrau
F Ferrau
Endocrine Unit, University Hospital AOU Policlinico G. Martino, Messina, Italy
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F Gatto
F Gatto
IRCCS Ospedale Policlinico San Martino, Genova, Genoa, Italy
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C Grasselli
C Grasselli
Cardiovascular Medicine Unit, AUSL-IRCCS, Reggio Emilia, Italy
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P van Houten
P van Houten
Department of Internal Medicine, Division of Endocrinology, Radboud University Medical Center, Nijmegen, Netherlands
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C Hoybye
C Hoybye
Department of Endocrinology, Karolinska University Hospital and Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
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A M Isidori
A M Isidori
Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy
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A Kyrilli
A Kyrilli
Department of Endocrinology, Hôpital Universitaire de Bruxelles, Hôpital Erasme, Brussels, Belgium
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P Loli
P Loli
Division of Endocrinology, San Raffaele Vita-Salute University, IRCCS San Raffaele Hospital Milan, Italy
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D Maiter
D Maiter
Department of Endocrinology, Cliniques universitaires Saint-Luc – UCLouvain, Brussels, Belgium
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E Nowak
E Nowak
Department of Medicine IV, LMU University Hospital, LMU Munich, Munich, Germany
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R Pivonello
R Pivonello
Dipartimento di Medicina Clinica e Chirurgia, Sezione di Endocrinologia, Diabetologia, Andrologia e Nutrizione, Università “Federico II” di Napoli, Naples, Italy
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O Ragnarsson
O Ragnarsson
Sahlgrenska Academy, Wallenberg Centre for Molecular and Translational Medicine, Institute of Medicine (O.R.), University of Gothenburg, Sweden
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R V Steenaard
R V Steenaard
Department of Internal Medicine, Máxima MC, Veldhoven, Netherlands
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N Unger
N Unger
University Hospital Essen, Department of Endocrinology, Diabetes and Metabolism, Essen, Germany
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A van de Ven
A van de Ven
Department of Internal Medicine, Division of Endocrinology, Radboud University Medical Center, Nijmegen, Netherlands
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S M Webb
S M Webb
Department of Endocrinology, Fundacio de Gestio Sanitaria Hospital de la Santa Creu i Sant Pau, IR-SantPau and CIBERER Unit 747 (ISCIII), Barcelona, Spain
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D Yeste
D Yeste
Pediatric Endocrinology Service, Hospital Universitari Vall d’Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain. CIBER Enfermedades Raras, Instituto Carlos III, Madrid, Spain
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S F Ahmed
S F Ahmed
Department of Medicine, Division of Endocrinology, Leiden University Medical Centre, Leiden, Netherlands
University of Glasgow, Office for Rare Conditions, Glasgow, UK
University of Glasgow, Developmental Endocrinology Research Group, Royal Hospital for Children, Glasgow, UK
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University of Glasgow, Office for Rare Conditions, Glasgow, UK
University of Glasgow, Developmental Endocrinology Research Group, Royal Hospital for Children, Glasgow, UK
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A M Pereira
A M Pereira
Department of Endocrinology & Metabolism, Amsterdam University Medical Centre, Amsterdam, Noord-Holland, Netherlands
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.93 ± 1.53 Obesity: n (%) 49 (34.8%) 23 (33.3%) 4 (33.3%) 76 (34.2%) Hypertension: n (%) 90 (63.8%) 49 (71%) 9 (75%) 148 (66.7%) Diabetes: n (%) 30 (21.3%) 17 (24.6%) 5 (41.7%) 52 (23.4%) Previous VTE
Ramjan Sanas Mohamed
Ramjan Sanas Mohamed
Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Biyaser Abuelgasim
Biyaser Abuelgasim
Imperial College School of Medicine, Department of Biochemistry, Imperial College Healthcare NHS Trust, London, UK
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Sally Barker
Sally Barker
Imperial College School of Medicine, Department of Biochemistry, Imperial College Healthcare NHS Trust, London, UK
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Hemanth Prabhudev
Hemanth Prabhudev
Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Niamh M Martin
Niamh M Martin
Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
Division of Diabetes, Endocrinology and Metabolism, Imperial College London, London, UK
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Division of Diabetes, Endocrinology and Metabolism, Imperial College London, London, UK
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Karim Meeran
Karim Meeran
Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
Division of Diabetes, Endocrinology and Metabolism, Imperial College London, London, UK
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Division of Diabetes, Endocrinology and Metabolism, Imperial College London, London, UK
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Emma L Williams
Emma L Williams
Department of Biochemistry, Imperial College Healthcare NHS Trust, London, UK
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Sarah Darch
Sarah Darch
Department of Biochemistry, Imperial College Healthcare NHS Trust, London, UK
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Whitlock Matthew
Whitlock Matthew
Department of Biochemistry, Imperial College Healthcare NHS Trust, London, UK
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Tricia Tan
Tricia Tan
Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
Division of Diabetes, Endocrinology and Metabolism, Imperial College London, London, UK
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Division of Diabetes, Endocrinology and Metabolism, Imperial College London, London, UK
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Florian Wernig
Florian Wernig
Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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adrenal adenomas, two with CS due to adrenocortical cancers and one patient had CS due to an ectopic ACTH source. The latter patient underwent inferior petrosal sinus sampling to exclude a central source of ACTH with a confirmed ACTH source from diffuse
Dafydd Aled Rees
Dafydd Aled Rees
Cardiff University, Cardiff, United Kingdom
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Deborah P Merke
Deborah P Merke
National Institutes of Health Clinical Center and the Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, USA
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Wiebke Arlt
Wiebke Arlt
MRC LMS, London, United Kingdom
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Aude Brac De La Perriere
Aude Brac De La Perriere
Hospices Civils de Lyon - GHE - Endocrinologie, Bron, France
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Angelica Linden Hirschberg
Angelica Linden Hirschberg
Karolinska Institute, Solna, Sweden
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Anders Juul
Anders Juul
Department of Growth and Reproduction, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark, and Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
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John Newell-Price
John Newell-Price
The University of Sheffield, Sheffield, United Kingdom
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Alessandro Prete
Alessandro Prete
University of Birmingham, Birmingham, United Kingdom
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Nicole Reisch
Nicole Reisch
Endokrinologie, Nephrologie und weitere Sektionen - Medizinische Klinik und Poliklinik IV - Campus Innenstadt, München, Germany
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Nike M Stikkelbroeck
Nike M Stikkelbroeck
Radboud University Nijmegen, Nijmegen, Netherlands
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Philippe A Touraine
Philippe A Touraine
University Hospitals Pitié Salpêtrière - Charles Foix, Paris, France
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Alex Lewis
Alex Lewis
Neurocrine Biosciences Inc, London, United Kingdom
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John Porter
John Porter
Neurocrine Biosciences Inc, London, United Kingdom
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Helen Coope
Helen Coope
Neurocrine Biosciences Inc, London, United Kingdom
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Richard J Ross
Richard J Ross
The University of Sheffield, Sheffield, United Kingdom
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invited to participate in a single-arm, open-label extension study. The study protocols were approved by The East Midlands − Leicester Central Research Ethics Committee (ref: 16/EM/0278) and the Medicines and Healthcare Products Regulatory Agency (NCT
Paola Parra Ramírez
Paola Parra Ramírez
Endocrinology & Nutrition Department, La Paz University Hospital, Madrid, Spain
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Patricia Martín Rojas-Marcos
Patricia Martín Rojas-Marcos
Endocrinology & Nutrition Department, La Paz University Hospital, Madrid, Spain
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Miguel Paja Fano
Miguel Paja Fano
Endocrinology & Nutrition Department, Hospital Universitario de Basurto, Bilbao, Spain
Medicine Department, Basque Country University, Bilbao, Spain
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Medicine Department, Basque Country University, Bilbao, Spain
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Marga González Boillos
Marga González Boillos
Endocrinology & Nutrition Department, Hospital Universitario de Castellón, Castellón, Spain
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Eider Pascual-Corrales
Eider Pascual-Corrales
Endocrinology & Nutrition Department, Hospital Universitario Ramón y Cajal, Madrid, Spain
Instituto de Investigación Biomédica Ramón y Cajal (IRYCIS), Madrid, Spain
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Instituto de Investigación Biomédica Ramón y Cajal (IRYCIS), Madrid, Spain
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Ana García-Cano
Ana García-Cano
Biochemistry Department, Hospital Universitario Ramón y Cajal, Madrid, Spain
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Jorge Gabriel Ruiz-Sanchez
Jorge Gabriel Ruiz-Sanchez
Endocrinology & Nutrition Department, Hospital Fundación Jiménez Díaz, Madrid, Spain
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Almudena Vicente
Almudena Vicente
Endocrinology & Nutrition Department, Complejo Universitario de Toledo, Toledo, Spain
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Emilia Gómez-Hoyos
Emilia Gómez-Hoyos
Endocrinology & Nutrition Department, Hospital Clínico Universitario de Valladolid, Valladolid, Spain
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Rui Ferreira
Rui Ferreira
Endocrinology & Nutrition Department, Hospital Universitario de La Princesa, Madrid, Spain
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Iñigo García Sanz
Iñigo García Sanz
General & Digestive Surgery Department, Hospital Universitario de La Princesa, Madrid, Spain
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Mònica Recasens
Mònica Recasens
Endocrinology & Nutrition Department, Hospital Josep Trueta, Servei d’Endocrinologia, Girona, Spain
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Begoña Pla Peris
Begoña Pla Peris
Endocrinology & Nutrition Department, Hospital Universitario de Castellón, Castellón, Spain
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Rebeca Barahona San Millan
Rebeca Barahona San Millan
Endocrinology & Nutrition Department, Hospital Josep Trueta, Servei d’Endocrinologia, Girona, Spain
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María José Picón César
María José Picón César
Endocrinology & Nutrition Department, Complejo Hospitalario Málaga (Hospital Virgen de la Victoria), IBIMA Malaga, Malaga, Spain
CIBEROBN, Madrid, Spain
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CIBEROBN, Madrid, Spain
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Patricia Díaz Guardiola
Patricia Díaz Guardiola
Endocrinology & Nutrition Department, Hospital Universitario Infanta Sofía, Madrid, Spain
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Juan Jesús García González
Juan Jesús García González
Endocrinology & Nutrition Department, Hospital Universitario Virgen de la Macarena, Sevilla, Spain
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Carolina Perdomo
Carolina Perdomo
Endocrinology & Nutrition Department, Clínica Universidad de Navarra, Pamplona, Spain
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Laura Manjón
Laura Manjón
Endocrinology & Nutrition Department, Hospital Universitario Central de Asturias, Oviedo, Spain
Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain
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Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain
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Rogelio García-Centeno
Rogelio García-Centeno
Endocrinology & Nutrition Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain
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Juan Carlos Percovich
Juan Carlos Percovich
Endocrinology & Nutrition Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain
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Ángel Rebollo Román
Ángel Rebollo Román
Endocrinology & Nutrition Department, Hospital Reina Sofía, Córdoba, Spain
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Paola Gracia Gimeno
Paola Gracia Gimeno
Endocrinology & Nutrition Department, Hospital Royo Villanova, Zaragoza, Spain
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Cristina Robles Lázaro
Cristina Robles Lázaro
Endocrinology & Nutrition Department, Hospital Universitario de Salamanca, Salamanca, Spain
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Manuel Morales
Manuel Morales
Biochemistry and Molecular Genetics Department-CDB, Hospital Clinic, IDIBAPS, CIBERehd, Barcelona, Spain
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Felicia Hanzu
Felicia Hanzu
Endocrinology & Nutrition Department, Hospital Clinic, Barcelona, Spain
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Marta Araujo-Castro
Marta Araujo-Castro
Endocrinology & Nutrition Department, Hospital Universitario Ramón y Cajal, Madrid, Spain
Instituto de Investigación Biomédica Ramón y Cajal (IRYCIS), Madrid, Spain
University of Alcalá, Madrid, Spain
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Instituto de Investigación Biomédica Ramón y Cajal (IRYCIS), Madrid, Spain
University of Alcalá, Madrid, Spain
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diabetes mellitus, obesity, dyslipidemia and sleep apnea syndrome. Information about pharmacological history with antihypertensive (type, number, and doses), oral antidiabetic and lipid-lowering medications, potassium supplements and antiplatelet agents was
