University of Alcalá, Madrid, Spain
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appropriate, taking into account the recommendation of the ESE/ENSAT guidelines ( 16 ) and the studies demonstrating an increase in cardiometabolic and mortality risk above this threshold ( 28 ). Nevertheless, the use of a less strict criterion to define ACS
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Medicine Department, Basque Country University, Bilbao, Spain
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Instituto de Investigación Biomédica Ramón y Cajal (IRYCIS), Madrid, Spain
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CIBEROBN, Madrid, Spain
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Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain
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Instituto de Investigación Biomédica Ramón y Cajal (IRYCIS), Madrid, Spain
University of Alcalá, Madrid, Spain
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). Patients with PA have a higher cardiometabolic risk profile, with four times increased risk for stroke and six times for nonfatal myocardial infarction, than patients with essential hypertension (EHT) matched by blood pressure (BP), sex, and age ( 2 , 3
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Clinical Research Centre, Medical University of Bialystok, Bialystok, Poland
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patients with MACS ( 22 ) and NFAT may be associated with increased cardiometabolic risk during follow-up ( 17 ). The aim of the present study was to analyse different cardiovascular risk factors in patients with MACS in comparison to those with NFAT
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Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
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Institute of Applied Health Research, University of Birmingham, Birmingham, UK
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Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
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Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
Medical Research Council London Institute of Medical Sciences, London, UK
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Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
NIHR Birmingham Biomedical Research Centre, University of Birmingham and University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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knowledge of the condition and novel treatment strategies, patients with PAI still face increased morbidity and mortality risk. Most notably, several studies have proposed that these patients may carry an increased risk of infections, which are a major
Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
Department of Clinical Biochemistry, North West London Pathology, London, UK
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Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
Department of Clinical Biochemistry, North West London Pathology, London, UK
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) prednisolone ( 4 ). Over-replacement with glucocorticoids avoids adrenal crisis at the expense of an increased risk of developing multiple comorbidities, including obesity, diabetes, cardiovascular disease, and osteoporosis ( 5 ). It is crucial to achieve an
Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
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University Rehabilitation Institute, Ljubljana, Slovenia
FAMNIT, University of Primorska, Koper, Slovenia
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Clinical Institute of Radiology, University Medical Centre Ljubljana, Ljubljana, Slovenia
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Clinical Institute of Radiology, University Medical Centre Ljubljana, Ljubljana, Slovenia
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, while CT descriptive findings were less important. Seven out of our 85 patients with BPA (8%) (Supplementary Table 2) were classified as LPA and would have been put at risk of inappropriate adrenalectomy if the SPACE score alone would direct the