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in both these groups the relationship between bone metastases, primary type/site of NET, laboratory parameters (chromogranin A (CgA), calcium, phosphate, parathyroid hormone (PTH) and vitamin D) and proliferation markers (Ki-67 and mitotic index
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Royal Marsden Hospital, London, UK
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parathyroid hormone (PTH) has been described in several case reports ( 52 , 53 ). ICPI-induced hypoparathyroidism differs mechanistically from the other endocrine irAEs. Activating autoantibodies against the calcium-sensing receptor disrupt the glands
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Endocrinology, Abdominal Centre, University of Helsinki and HUS, Helsinki, Finland
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Events version 5.0 ( 16 ). Before treatment initiation, a standard spectrum of laboratory tests was taken including whole blood cell count (WBC), sodium, potassium, calcium, creatinine, glomerular filtration rate, aspartate and alanine aminotransferases
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. Within Endo-ERN, eight different Main Thematic Groups (MTGs) are defined: MTG1 Adrenal; MTG2 Disorders of Calcium & Phosphate Homeostasis; MTG3 Genetic Disorders of Glucose & Insulin Homeostasis; MTG4 Genetic Endocrine Tumor Syndromes; MTG5 Growth