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). The present study investigates the effect of high TSH levels on insulin signal transduction in adipose tissue, and the role of ER stress in this process. We found that TSH can induce insulin resistance in adipose tissue, and the mechanism through which
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Talukdar S Heine M Fischer AW Krott LM Nilsson SK Brenner MB Heeren J Scheja L . FGF21 lowers plasma triglycerides by accelerating lipoprotein catabolism in white and brown adipose tissues . Cell Metabolism 2016 23 441 – 453 . ( https
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assess body weight excess and adipose tissue overload being linearly associated with a greater risk of thyroid cancer ( 54 ). The risk seems to be affected by gender, with women being exposed to a greater risk of differentiated thyroid cancer than men are
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was updated in 2017 ( 8 ). This later guidance noted that subjects’ ethnicity, location and adiposity, in particular, affected the upper limits of ‘normal’ thyroid function, as expressed by the reference range. As a result, the US guidelines advocate