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Department of Endocrinology, Austin Health, Melbourne, Australia
Division of Endocrinology, Diabetes and Metabolism, Northwell, Great Neck, New York, USA
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Department of Cardiology, Austin Health, Melbourne Australia
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Olivia Newton-John Cancer Research Institute, Austin Health, Melbourne, Australia
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Department of Endocrinology, Austin Health, Melbourne, Australia
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Department of Endocrinology, Austin Health, Melbourne, Australia
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Introduction In postmenopausal women with early oestrogen receptor-positive (ER+) breast cancer, aromatase inhibitors (AIs) are the mainstay of adjuvant therapy ( 1 ). In this population, AI therapy is directed at the oestrogen axis and
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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, colorectum, and breast ( 11 , 12 , 13 ). However, in a large number of studies on insulin and cancer, only one study has examined the relationship between insulin and BTC. But because only two cases of BTC occurred in 2156 insulin users, the study by
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risk of breast cancer in postmenopausal women with normal body mass index: a secondary analysis of a randomized clinical trial and observational study . JAMA Oncology 2019 5 155 – 163 . ( https://doi.org/10.1001/jamaoncol.2018.5327 ) 21 Anjana M
School of Public Health, Ningxia Medical University, Yinchuan, Ningxia, China
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Key Laboratory of Environmental Factors and Chronic Disease Control, Ningxia Medical University, Yinchuan, Ningxia, China
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Key Laboratory of Environmental Factors and Chronic Disease Control, Ningxia Medical University, Yinchuan, Ningxia, China
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Key Laboratory of Environmental Factors and Chronic Disease Control, Ningxia Medical University, Yinchuan, Ningxia, China
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& Słomińska E . Serum fatty acid profiles in breast cancer patients following treatment . BMC Cancer 2023 23 433 . ( https://doi.org/10.1186/s12885-023-10914-2 ) 9 Ekström S Sdona E Klevebro S Hallberg J Georgelis A Kull I Melén E Risérus
Department of Anatomy, Shanxi Medical University, Taiyuan, China
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). Numerous studies have demonstrated that Txnip is downregulated in various cancers and human cancer cells, such as breast cancer, stomach cancer, lung cancer, colon cancer, cervical cancer, gastrointestinal cancer, prostate cancer, cutaneous T
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in inflammatory cells . Free Radical Research Communications 1991 14 195 – 208 . ( https://doi.org/10.3109/10715769109088949 ) 40 Maggiolini M Donze O Jeannin E Ando S Picard D . Adrenal androgens stimulate the proliferation of breast
Comprehensive Heart Failure Center, University & University Hospital Würzburg, Würzburg, Germany
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Department of Psychiatry, Psychosomatics and Psychotherapy, University Hospital, University of Würzburg, Würzburg, Germany
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Division of Cardiology, Department of Internal Medicine I, University Hospital, University of Würzburg, Würzburg, Germany
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Department of General, Visceral, Transplant, Vascular, and Pediatric Surgery, University Hospital, University of Würzburg, Würzburg, Germany
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Division of Cardiology, Department of Internal Medicine I, University Hospital, University of Würzburg, Würzburg, Germany
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Division of Cardiology, Department of Internal Medicine I, University Hospital, University of Würzburg, Würzburg, Germany
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Comprehensive Heart Failure Center, University & University Hospital Würzburg, Würzburg, Germany
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>40 kg/m 2 or • BMI >35 kg/m 2 with severe comorbidities • Indication for Roux-en-Y gastric bypass surgery • Ability to perform cardiopulmonary exercise testing • Written informed consent Exclusion criteria • Pregnancy or breast feeding