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Yi Chen Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China

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Wen Zhang Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China

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Chi Chen Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China

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Yuying Wang Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China

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Ningjian Wang Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China

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Yingli Lu Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China

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Introduction Type 2 diabetes mellitus (T2DM) is associated with an increased fracture risk ( 1 , 2 , 3 ), which has aroused great concern. One of the most commonly used indicators to assess fracture risk is the bone mineral density (BMD

Article Type:
Research Article
Collections:
Metabolic Syndrome and Diabetes
DOI:
https://doi.org/10.1530/EC-21-0484
Volume/Issue:
Volume 11: Issue 3
Open access
Zhiyan Yu Department of Endocrinology, Shanghai Fifth People’s Hospital, Fudan University, Shanghai, China

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Yueyue Wu Department of Endocrinology, Shanghai Fifth People’s Hospital, Fudan University, Shanghai, China

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Rui Zhang Department of Endocrinology, Shanghai Fifth People’s Hospital, Fudan University, Shanghai, China

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Yue Li Department of Endocrinology, Shanghai Fifth People’s Hospital, Fudan University, Shanghai, China

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Shufei Zang Department of Endocrinology, Shanghai Fifth People’s Hospital, Fudan University, Shanghai, China

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Jun Liu Department of Endocrinology, Shanghai Fifth People’s Hospital, Fudan University, Shanghai, China

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Introduction Osteoporosis is a systemic bone disease characterized by decrease in bone mass and damage to the microstructure of bone tissue, resulting in increased bone fragility and susceptibility to fracture ( 1 ). Pain due to osteoporosis

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Metabolic Syndrome and Diabetes
DOI:
https://doi.org/10.1530/EC-22-0174
Volume/Issue:
Volume 11: Issue 11
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Nobuo Matsuura Department of Pediatrics, Kitasato University School of Medicine, Sagamihara, Japan

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Tadashi Kaname Department of Genome Medicine, National Research Institute for Child Health and Development, Tokyo, Japan

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Norio Niikawa Health Sciences University of Hokkaido, Sapporo, Japan

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Yoshihide Ooyama Department of Pediatrics, Kitasato University School of Medicine, Sagamihara, Japan

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Osamu Shinohara Shinohara Child Clinic, Machida, Japan

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Yukifumi Yokota Department of Pediatrics, Kitasato University School of Medicine, Sagamihara, Japan

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Shigeyuki Ohtsu Department of Pediatrics, Kitasato University School of Medicine, Sagamihara, Japan

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Noriyuki Takubo Department of Pediatrics, Kitasato University School of Medicine, Sagamihara, Japan

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Kazuteru Kitsuda Department of Pediatrics, Kitasato University School of Medicine, Sagamihara, Japan

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Keiko Shibayama Department of Pediatrics, Kitasato University School of Medicine, Sagamihara, Japan

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Fumio Takada Department of Medical Genetics, Kitasato University Graduate School of Medical Science, Sagamihara, Japan

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Akemi Koike Miyanosawa Child Clinic, Sapporo, Japan

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Hitomi Sano Department of Pediatric, Sapporo City General Hospital, Sapporo, Japan

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Yoshiya Ito Department of Clinical Medicine, Japanese Red Cross Hospital Collage of Nursing, Kitami, Japan

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Kenji Ishikura Department of Pediatrics, Kitasato University School of Medicine, Sagamihara, Japan

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metacarpals are common in patients with ACRO, Turner syndrome, PHP and other congenital skeletal abnormalities ( 11 ). In the pediatric endocrine clinic, we usually take hand X-rays for the evaluation of bone age in patients with congenital hypothyroidism

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Metabolic Syndrome and Diabetes
DOI:
https://doi.org/10.1530/EC-22-0151
Volume/Issue:
Volume 11: Issue 10
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Qian Deng Graduate College of Anhui University of Chinese Medicine, Hefei, China

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Yue Zhu Graduate College of Anhui University of Chinese Medicine, Hefei, China

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Mengmeng Zhang Graduate College of Anhui University of Chinese Medicine, Hefei, China

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Aihua Fei Department of Endocrinology, The Second Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, China

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Jiaqi Liang Graduate College of Anhui University of Chinese Medicine, Hefei, China

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Jinjin Zheng Graduate College of Anhui University of Chinese Medicine, Hefei, China

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Qingping Zhang College of Acupuncture-moxibustion and Tuina, Anhui University of Chinese Medicine, Hefei, China

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Tong Cheng Department of Geriatrics, Zhongshan Hospital, Fudan University, Shanghai, China

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Xia Ge Department of Endocrinology, The Second Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, China

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). Persistent hyperglycemia of diabetes is the basis of its chronic complications, multiple organs are involved in it, such as the kidneys, retina, bones and joints, nervous system (peripheral, central), cardiovascular system, etc. ( 3 ). Diabetes greatly

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Metabolic Syndrome and Diabetes
DOI:
https://doi.org/10.1530/EC-22-0419
Volume/Issue:
Volume 12: Issue 3
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Annalisa Blasetti Department of Paediatrics, University of Chieti, Chieti, Italy

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Valeria Castorani Department of Paediatrics, University of Chieti, Chieti, Italy

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Nella Polidori Department of Paediatrics, University of Chieti, Chieti, Italy

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Ilaria Mascioli Department of Paediatrics, University of Chieti, Chieti, Italy

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Francesco Chiarelli Department of Paediatrics, University of Chieti, Chieti, Italy

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Cosimo Giannini Department of Paediatrics, University of Chieti, Chieti, Italy

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extend these data to other ethnic groups; therefore, further studies in this sense will be necessary to confirm such results according to this relevant factor. Finally, the lack of data regarding parental height and especially bone age might not offer a

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Metabolic Syndrome and Diabetes
DOI:
https://doi.org/10.1530/EC-22-0370
Volume/Issue:
Volume 12: Issue 4
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Niels B Dalsgaard Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark

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Lærke S Gasbjerg Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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Laura S Hansen Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark

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Dennis S Nielsen Department of Food Science, Faculty of Science, University of Copenhagen, Copenhagen, Denmark

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Torben S Rasmussen Department of Food Science, Faculty of Science, University of Copenhagen, Copenhagen, Denmark

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Filip K Knop Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Steno Diabetes Center Copenhagen, Gentofte, Denmark

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Gasbjerg LS Helsted MM Hansen LS Hansen NL Skov-Jeppesen K Hartmann B Holst JJ Vilsbøll T & Knop FK . Acarbose diminishes postprandial suppression of bone resorption in patients with type 2 diabetes . Bone 2023 170 116687 . ( https

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Metabolic Syndrome and Diabetes
DOI:
https://doi.org/10.1530/EC-24-0052
Volume/Issue:
Volume 13: Issue 7
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Yuan Huang Department of Cardiology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China

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Yunyun Hu The First Affiliated Hospital, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China

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Bingshu Bao The Second People’s Hospital, Luqiao, Taizhou, Zhejiang, China

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use weight and height but do not take into account the differences in the proportions of muscle, bone, and fat. Notably, bone density is greater than muscle, and muscle density is greater than fat; hence, all three have the smallest bone volume and the

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Metabolic Syndrome and Diabetes
DOI:
https://doi.org/10.1530/EC-23-0291
Volume/Issue:
Volume 12: Issue 11
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Merlin C Thomas Department of Diabetes, Central Clinical School, Monash University, Melbourne, VIC, Australia

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Brendon L Neuen The George Institute for Global Health, Sydney, NSW, Australia

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Stephen M Twigg The University of Sydney School of Medicine, Sydney, NSW, Australia
Department of Endocrinology, Royal Prince Alfred Hospital, Sydney, NSW, Australia

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Mark E Cooper Department of Diabetes, Central Clinical School, Monash University, Melbourne, VIC, Australia

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Sunil V Badve The George Institute for Global Health, Sydney, NSW, Australia
Department of Renal Medicine, St George Hospital, Sydney, NSW, Australia
Faculty of Medicine and Health, University of New South Wales, Sydney, NSW, Australia

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in their CVOTs, HF or kidney RCTs, making it unlikely that there is any drug class risk. Bone fractures Bone fractures are a common and serious condition in older adults. Treatment of adults PPAR gamma agonists (e.g. pioglitazone) is

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Metabolic Syndrome and Diabetes
DOI:
https://doi.org/10.1530/EC-23-0005
Volume/Issue:
Volume 12: Issue 8
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Yee-Ming M Cheung Department of Medicine, The University of Melbourne, Austin Health, Melbourne, Australia
Department of Endocrinology, Austin Health, Melbourne, Australia
Division of Endocrinology, Diabetes and Metabolism, Northwell, Great Neck, New York, USA

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Rudolf Hoermann Department of Medicine, The University of Melbourne, Austin Health, Melbourne, Australia

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Karen Van Department of Endocrinology, Austin Health, Melbourne, Australia

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Damian Wu Department of Medicine, The University of Melbourne, Austin Health, Melbourne, Australia

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Jenny Healy Department of Medicine, The University of Melbourne, Austin Health, Melbourne, Australia

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Bella Halim Department of Endocrinology, Austin Health, Melbourne, Australia

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Manjri Raval Department of Endocrinology, Austin Health, Melbourne, Australia

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Maria McGill Department of Radiology, Austin Health, Melbourne, Australia

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Ali Al-Fiadh Department of Medicine, The University of Melbourne, Austin Health, Melbourne, Australia
Department of Cardiology, Austin Health, Melbourne Australia

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Michael Chao Olivia Newton-John Cancer Research and Wellness Centre, Austin Health, Melbourne, Australia

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Shane White Olivia Newton-John Cancer Research and Wellness Centre, Austin Health, Melbourne, Australia

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Belinda Yeo Olivia Newton-John Cancer Research and Wellness Centre, Austin Health, Melbourne, Australia
Olivia Newton-John Cancer Research Institute, Austin Health, Melbourne, Australia

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Jeffrey D Zajac Department of Medicine, The University of Melbourne, Austin Health, Melbourne, Australia
Department of Endocrinology, Austin Health, Melbourne, Australia

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Mathis Grossmann Department of Medicine, The University of Melbourne, Austin Health, Melbourne, Australia
Department of Endocrinology, Austin Health, Melbourne, Australia

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Metabolism 2018 103 1948 – 1957 . ( https://doi.org/10.1210/jc.2017-02449 ) 19 Shea KL Gavin KM Melanson EL Gibbons E Stavros A Wolfe P Kittelson JM Vondracek SF Schwartz RS Wierman ME , Body composition and bone mineral density after

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Metabolic Syndrome and Diabetes
DOI:
https://doi.org/10.1530/EC-23-0076
Volume/Issue:
Volume 12: Issue 10
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Xianghe Chen College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China

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Xinyu Zeng College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China

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Xiao Qiu College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China

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Chi Liu College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China

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Pengcheng Lu College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China

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Ziming Shen College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China

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Xiangxiang Zhou College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China

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Kang Yang Department of Rehabilitation Medicine, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou, Jiangsu, China

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K Fan Z Tang Z , et al. Bone autophagy: a potential way of exercise-mediated Meg3/P62/Runx2 pathway to regulate bone formation in T2DM mice . Diabetes, Metabolic Syndrome and Obesity 2021 14 2753 – 2764 . ( https://doi.org/10.2147/DMSO.S299744

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Metabolic Syndrome and Diabetes
DOI:
https://doi.org/10.1530/EC-23-0448
Volume/Issue:
Volume 13: Issue 3
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