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. In MEN1, lesions of parathyroid glands have the highest penetrance; they manifest with primary hyperparathyroidism (PHPT). Conversely, PHPT is a powerful etiological factor that can lead to bone disorders including the significant decrease in bone
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prevalence due to the more favorable prognosis ( 3 ). In Europe, the number of patients affected by NET in 2016 was estimated to be 292,971 ( 4 ). The skeletal system is a common site of metastasis for many solid tumors, but bone involvement by NETs has
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Introduction Bone metastasis is the second most common type of distant metastasis in differentiated thyroid cancer (DTC) after lung metastasis, with an incidence of 2–13%, strongly suggesting a poor prognosis ( 1 , 2 , 3 , 4 , 5 , 6
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specialists. Topics will cover bone health, growth hormone deficiency, the impact of different radiotherapy techniques on the hypothalamic–pituitary axis, risk assessment for second cancers, as well as strategies for international collaboration and different
Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
Garvan Institute of Medical Research, New South Wales, Australia
School of Medical Sciences, University of New South Wales, New South Wales, Australia
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Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
Department of Diabetes and Endocrinology, Westmead Hospital, New South Wales, Australia
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Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
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Faculty of Medicine, Health and Human Sciences, Macquarie University, New South Wales, Australia
Crown Princess Mary Cancer Centre, Westmead Hospital, New South Wales, Australia
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Endocrine Research Unit, Department of Endocrinology, Odense University Hospital & Department of Clinical Research, Faculty of Health, University of Southern Denmark, Odense, Denmark
Steno Diabetes Center Odense, Odense University Hospital & Department of Clinical Research, Faculty of Health, University of Southern Denmark, Odense, Denmark
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Endocrine Research Unit, Department of Endocrinology, Odense University Hospital & Department of Clinical Research, Faculty of Health, University of Southern Denmark, Odense, Denmark
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. Inclusion criteria were men aged between 50 and 80 years with histologically confirmed prostate cancer of early (localised prostate cancer disease without metastases) or advanced-stage prostate cancer (metastatic prostate cancer with bone involvement only
Leeds Institute for Cardiovascular and Metabolic Medicine (LICAMM), University of Leeds, Leeds, UK
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Leeds Institute for Cardiovascular and Metabolic Medicine (LICAMM), University of Leeds, Leeds, UK
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Leeds Institute of Medical Research, University of Leeds, UK
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Leeds Institute for Cardiovascular and Metabolic Medicine (LICAMM), University of Leeds, Leeds, UK
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triglyceride levels of the CCS were however normal ( 15 ). In 23 recipients of childhood bone marrow transplant (BMT) for haematological malignancies ( n = 17) or aplastic anaemia/myelodysplasia, 9 had hypertriglyceridaemia and 5 had low HDL values. Only mean
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Department of Florey Institute, University of Melbourne, Parkville, Victoria, Australia
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adequate serum levels and physiologic response. The most compelling of these was bone remodeling markers showing a strong antiresorptive effect of E2 administration over 6 months ( 31 ). Additionally, E2 treatment reduced average daily hot flush frequency
Center for Neuroendocrine Tumors, ENETS Center of Excellence, Netherlands Cancer Institute, University Medical Center Utrecht, Utrecht, The Netherlands
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Department of Clinical Chemistry, The Netherlands Cancer Institute, Amsterdam, The Netherlands
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Department of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands
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Center for Neuroendocrine Tumors, ENETS Center of Excellence, Netherlands Cancer Institute, University Medical Center Utrecht, Utrecht, The Netherlands
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to better disease staging (e.g. primary tumor/bone metastasis) and subsequently change of management while somatostatin receptor expression can be used to select patients for peptide receptor radionuclide therapy (PRRT) ( 13 , 14 , 15 , 16
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Centre de Recherche en Cancérologie de Lyon, UMR Inserm 1052 CNRS 5286, Lyon Cedex 08, France
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University of Lyon, Université Lyon 1, France
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University of Lyon, Université Lyon 1, France
Hospices Civils de Lyon, Institut de Pathologie Est, Bron Cedex, France
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Hospices Civils de Lyon, Hôpital Edouard Herriot, Gastroentérologie, Lyon Cedex 03, France
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University of Lyon, Université Lyon 1, France
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University of Lyon, Université Lyon 1, France
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, n (%) Liver 199 (32.4) 84 (49.4) 115 (25.8) <0.001 Distant lymph nodes 73 (11.9) 33 (19.4) 40 (9.0) 0.002 Bone 65 (10.6) 28 (16.5) 37 (8.3) 0.08 Peritoneum 49 (8.0) 20 (11.8) 29 (6