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( 19 , 20 ). In addition, high plasma aldosterone decreases the plasma level of potassium, which influences reabsorption of phosphate. Decreased serum phosphate leads to absorption of intestinal calcium, bone resorption, and calcitriol synthesis, which
IRCCS, Istituto Auxologico Italiano, Milan, Italy
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.5 Decreased libido 32.5 12.5 Bone problems 23.1 14.4 Infections 23.8 10.3 Glucose intolerance 17.2 8.4 Blood clot 5.3 Pain(s) 3.1 Vision problems 2.8 Headache 2.5 Cravings
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were determined by a review of medical records. Study design Patients who did not receive glucocorticoid replacement were excluded. Data regarding clinical features (e.g. hirsutism, menstrual abnormalities, bone mineral density and metabolic
Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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difference in parameters, including bone density, HbA1C, blood pressure, body mass index, and waist circumference, between prednisolone and hydrocortisone use ( 5 , 10 , 13 , 14 ). There remains a paucity of evidence on the optimum prednisolone dose to
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prevalence of osteoporosis appears consistent with the findings of previous studies, which demonstrated either mildly reduced ( 28 ) or unchanged ( 29 ) bone mineral density in patients with PAI compared to the general population. The association in our study
International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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Pediatric Endocrinology Clinic, Department of Pediatrics, Aretaeio Hospital, Nicosia, Cyprus
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Department of Clinical Medicine, University of Copenhagen, Denmark
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,797 European and US men . Fertility and Sterility 2010 94 2128 – 2134 . ( https://doi.org/10.1016/j.fertnstert.2009.12.051 ) 27 Falhammar H Filipsson Nyström H Wedell A Brismar K & Thorén M . Bone mineral density, bone markers, and fractures in
Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER, Unidad 747), ISCIII, Spain
Department of Endocrinology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
Department of Medicine, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain
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CAH diagnosed due to excessive growth, pubic hair, advanced bone age More attentive clinical staff/paediatrician to immediately recognise CAH, especially in salt-wasting cases. Being taken seriously, not as anxious patients Possibility of preventing
National Institute of Endocrinology CI Parhon, Bucharest, Romania
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scan (MIBG/PET-CT not available at the time of diagnosis). Metastatic disease was defined as the presence of PHEO in a nonchromaffin-containing tissue site, such as lymph nodes, bone, liver, and lung. Imaging techniques used for primary tumors and
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is important for clinicians to be aware of the heterogeneity in endogenous glucocorticoid secretion to prevent over-replacement with potential deleterious effect on bone density and metabolic profile. Case 2 in our series is the third documented case
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JL Duthie EH Wilson CR Sasse EA Rudman I Mattson D . Elevated salivary cortisol in the evening in healthy elderly men and women: correlation with bone mineral density . Journals of Gerontology: Series A, Biological Sciences and Medical