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The role of kisspeptin and MKRN3 in the diagnosis of central precocious puberty in girls

Mei Li

Mei Li Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China

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Yanfei Chen

Yanfei Chen Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China

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Binrong Liao

Binrong Liao Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China

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Jing Tang

Jing Tang Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China

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Jingzi Zhong

Jingzi Zhong Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China

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Dan Lan

Dan Lan Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China

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blood specimens without anticoagulant were centrifuged at 4244 g for 10 min, and the resultant serum specimens were aliquoted and stored at –20°C. The serum LH, FSH, and estradiol (E2) levels were measured by chemiluminescence immunoassays (Mindray, CL