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Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands
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risk for failure to attain peak bone mass or for early loss of BD, due to estrogen deficiency at an early age ( 1 , 2 , 3 , 4 , 5 ). Consequently, women with POI are advised to use hormone replacement therapy (HRT) ( 6 ). In contrast to POI, the
TRIXY Center of Expertise, Leiden University Treatment and Expertise Centre (LUBEC), Sandifortdreef, Leiden, The Netherlands
Leiden Institute for Brain and Cognition, Leiden University, Wassenaarseweg, Leiden, The Netherlands
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TRIXY Center of Expertise, Leiden University Treatment and Expertise Centre (LUBEC), Sandifortdreef, Leiden, The Netherlands
Leiden Institute for Brain and Cognition, Leiden University, Wassenaarseweg, Leiden, The Netherlands
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TRIXY Center of Expertise, Leiden University Treatment and Expertise Centre (LUBEC), Sandifortdreef, Leiden, The Netherlands
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TRIXY Center of Expertise, Leiden University Treatment and Expertise Centre (LUBEC), Sandifortdreef, Leiden, The Netherlands
Department of Clinical, Neuro, and Developmental Psychology, Vrije Universiteit Amsterdam, Van der Boechorststraat, Amsterdam, The Netherlands
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TRIXY Center of Expertise, Leiden University Treatment and Expertise Centre (LUBEC), Sandifortdreef, Leiden, The Netherlands
Leiden Institute for Brain and Cognition, Leiden University, Wassenaarseweg, Leiden, The Netherlands
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. Neurocognitive impairments may serve as sensitive early predictors of behavioral problems in later life, may function as markers for children with an ‘at-risk’ development (e.g. identify those that do not meet age-specific norms for language, cognitive, and motor
Department of Growth and Reproduction, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
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diagnosed before puberty ( 1 ). Most patients are diagnosed during infertility workup in adulthood at an age where many years of potential preventive actions are lost. The hypothalamo–pituitary–gonadal (HPG) hormone axis shows varying activities during
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Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
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Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
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Division of Obstetrics and Fetal Medicine, Department of Obstetrics and Gynecology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
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be the best marker of ovarian reserve ( 1 , 4 ). It is widely used as a predictor of ovarian response in controlled ovarian stimulation and to predict age‐at‐menopause as well as primary ovarian insufficiency ( 5 , 6 , 7 ). Besides the role of AMH
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Hospices Civils de Lyon, Hôpital Femme-Mère-Enfant, Service de psychopathologie du développement, Bron, France
Hospices Civils de Lyon, Hôpital Femme-Mère-Enfant, Centre de biologie et pathologie Est, Service d’hormonologie, d’endocrinologie moléculaire et des maladies rares, Bron, France
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Centre National de Référence Maladies Rares du développement génital du fœtus à l’adulte DEV-GEN, Hospices Civils de Lyon, Bron, France
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Université Claude Bernard, Lyon, France
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Université Claude Bernard, Lyon, France
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Université Claude Bernard, Lyon, France
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and age at molecular diagnosis according to the year of birth. Due to an insufficient number of patients, no statistical trend analysis was performed. However, regarding the timing of molecular diagnosis, a statistical comparison was made between two
International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
Section of Biostatistics, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
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mineral content (BMC) in 62 patients with KS aged 5.9–20.6 years. Materials and methods Study population Patients with Klinefelter syndrome Patients eligible for this retrospective, observational tertiary center study at The Department of
Laboratory of Biotechnology, Environment, Food, and Health, Faculty of Sciences Dhar El Mahraz, Sidi Mohammed Ben Abdellah University, Fez, Morocco
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We conducted a retrospective analysis of all patients under the age of 18 years with suspected DSD. These patients were referred to the Pediatric Endocrinology Department and the Medical Genetics Laboratory at HASSAN II University Hospital of Fez
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age at presentation, patients with 46,XY were categorized as in minipubertal age (0 to ≤ 0.5 years), pre-pubertal age (> 0.5 to ≤ 9 years), pubertal age (> 9 years to ≤ 14 years) and post-pubertal age (> 14 years). A hCG-stimulated testosterone of <1
Leiden Institute for Brain and Cognition, Leiden, The Netherlands
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Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado
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regulation problems like emotional outbursts ( 4 ), anxiety symptoms ( 5 ), and depressive symptoms ( 6 ) are commonly present in SCT in the age range from school-aged children to adulthood. In addition, differences in physiological arousal (expressed in skin
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carried out in pregnant women ( 25 ) and women of reproductive age over the menstrual cycle ( 26 ), so it is unknown if this would be a sensitive method to detect changes in peripheral kisspeptin concentrations during pubertal development. In this