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Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
Danish Diabetes Academy, Odense University Hospital, Odense, Denmark
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Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
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Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
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Department of Biomedicine, Aarhus University, Aarhus, Denmark
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Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
Danish Diabetes Academy, Odense University Hospital, Odense, Denmark
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insulin-independent lowering of plasma glucose has several pleiotropic consequences that may contribute to overall cardioprotection ( 2 ). This includes a 2–2.5 kg weight loss and a significant impact on adipose tissue with an increase in lipid
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health, is increasing worldwide. Hence, exploring the mechanisms through which obesity occurs and finding effective prevention and treatment strategies are urgently required in the field of public health. Mammalian adipose tissue comprises white (WAT
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(adiponectin, IL-10) ( 4 ). Chronic inflammation in obese adipose tissues is characterized by a substantial infiltration of macrophages ( 5 ). In the context of prolonged positive energy homeostasis, adipose tissue undergoes expansion to accommodate increased
Department of Endocrinology, Austin Health, Melbourne, Australia
Division of Endocrinology, Diabetes and Metabolism, Northwell, Great Neck, New York, USA
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Department of Cardiology, Austin Health, Melbourne Australia
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Olivia Newton-John Cancer Research Institute, Austin Health, Melbourne, Australia
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Department of Endocrinology, Austin Health, Melbourne, Australia
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Department of Endocrinology, Austin Health, Melbourne, Australia
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oestrogen states ( 18 , 19 ) have been associated with increases in visceral adipose tissue (VAT), the changes which are often mitigated when oestradiol is added back ( 18 , 19 ). As a bidirectional relationship exists between excess VAT and the many
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is 34.3% and 16.4% respectively according to the China Chronic Disease and Nutrition Surveillance 2015–2019 survey ( 2 ). Although BMI has been adopted as a convenient tool to assess overall adiposity in epidemiological studies, it fails to evaluate
Postgraduate Program in Nutritional Sciences, Department of Nutrition, Center for Health Sciences, Federal University of Paraíba, João Pessoa, Paraíba, Brazil
University Centre of João Pessoa (UNIPE), João Pessoa, Paraíba, Brazil
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Postgraduate Program in Cognitive Neuroscience and Behavior, Center for Health Sciences, Federal University of Paraíba, João Pessoa, Paraíba, Brazil
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Department of Biorregulation, Health Sciences Institute, Federal University of Bahia, Bahia, Brazil
Postgraduate Program in Medicine and Health, Medical School of Medicine, Federal University of Bahia, Salvador, Bahia, Brazil
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(ACE2). ACE2 expression in the adipose tissue is greater than that in lung tissue, which means that adipose tissue may be vulnerable to coronavirus disease 2019 (COVID-19) infection ( 1 , 2 , 3 ). Obesity seems to predispose patients with SARS-CoV-2
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Global Health Research Institute, School of Human Development and Health, University of Southampton, Southampton, UK
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Introduction Adipose tissue is a functioning endocrine organ that produces a number of circulating hormones, including adiponectin. Unlike other adipokines, adiponectin levels fall with increasing total body fat mass ( 1 , 2 ). In addition
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Introduction Chemerin, an adipokine discovered in 2007, is mainly produced by adipose tissue and liver, which reaches different tissues and organs of the body through blood circulation ( 1 ). In recent years, many studies, including our
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adipose tissue distribution, rather than actual body fat, may play a more important role in all-cause mortality ( 20 , 21 ). While BMI is prevalently employed as a tool for the evaluation and classification of obesity, it harbors a significant limitation
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physiological processes and other factors ( 34 ). However, other studies have found that there was a more pronounced inverse association between abdominal adiposity and depressive symptoms in males compared to females. This counterintuitive link can be accounted