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Xianghe Chen
Xianghe Chen
College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China
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Xinyu Zeng
Xinyu Zeng
College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China
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Xiao Qiu
Xiao Qiu
College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China
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Chi Liu
Chi Liu
College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China
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Pengcheng Lu
Pengcheng Lu
College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China
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Ziming Shen
Ziming Shen
College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China
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Xiangxiang Zhou
Xiangxiang Zhou
College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China
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Kang Yang
Kang Yang
Department of Rehabilitation Medicine, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou, Jiangsu, China
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renal anti-fibrosis and inflammatory response through the protein effect of nicotinamide adenine dinucleotide+ (NAD+) coenzyme ( 3 , 4 ). Some studies found that the downregulation of Sirt1 expression in T2DM kidney led to renal interstitial fibrosis
Xinge Tao
Xinge Tao
Department of Endocrinology and Diabetes, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China
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Yanbin Xue
Yanbin Xue
Computer Net Center, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Rui Niu
Rui Niu
Department of Endocrinology and Diabetes, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China
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Wenjing Lu
Wenjing Lu
Department of Endocrinology and Diabetes, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China
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Huayan Yao
Huayan Yao
Computer Net Center, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Chunmei He
Chunmei He
Department of Endocrinology and Diabetes, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China
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Bin Cui
Bin Cui
Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Changqin Liu
Changqin Liu
Department of Endocrinology and Diabetes, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China
Xiamen Key Laboratory for Clinical Efficacy and Evidence-Based Research of Traditional Chinese Medicine, the First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China
Fujian Province Key Laboratory of Diabetes Translational Medicine, The First Affiliated Hospital of Xiamen University, School of medicine, Xiamen University, Xiamen, China
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Xiamen Key Laboratory for Clinical Efficacy and Evidence-Based Research of Traditional Chinese Medicine, the First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China
Fujian Province Key Laboratory of Diabetes Translational Medicine, The First Affiliated Hospital of Xiamen University, School of medicine, Xiamen University, Xiamen, China
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substantial health burden, especially on developing countries. According to the diabetes atlas of the International Diabetes Federation in 2022, China had the largest number of patients with T2DM and spent the second highest amount on diabetes ( 1 ). The
Li Qian
Li Qian
Department of Endocrinology, Sir Run Run Hospital, Nanjing Medical University, Nanjing, Jiangsu, China
Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China
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Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China
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Yuxiao Zhu
Yuxiao Zhu
Department of Endocrinology, Sir Run Run Hospital, Nanjing Medical University, Nanjing, Jiangsu, China
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Yan Luo
Yan Luo
Department of Endocrinology, Sir Run Run Hospital, Nanjing Medical University, Nanjing, Jiangsu, China
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Mu Zhang
Mu Zhang
Department of Endocrinology, Sir Run Run Hospital, Nanjing Medical University, Nanjing, Jiangsu, China
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Liping Yu
Liping Yu
Barbara Davis Center for Childhood Diabetes, University of Colorado School of Medicine, Aurora, Colorado, USA
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Yu Liu
Yu Liu
Department of Endocrinology, Sir Run Run Hospital, Nanjing Medical University, Nanjing, Jiangsu, China
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Tao Yang
Tao Yang
Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China
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Introduction Type 1 diabetes mellitus (T1DM) is well-defined as one of the most common and lifelong autoimmune diseases characterized by pancreatic β-cell destruction ( 1 , 2 ). Several autoantibodies, such as glutamic acid decarboxylase
Sarantis Livadas
Sarantis Livadas
Endocrine Unit, Athens Medical Centre, Athens, Greece
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Christina Bothou
Christina Bothou
Department of Endocrinology, Diabetology and Clinical Nutrition, University Hospital of Zurich, Zurich, Switzerland
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Justyna Kuliczkowska-Płaksej
Justyna Kuliczkowska-Płaksej
Department of Endocrinology, Diabetology and Isotope Therapy, University of Medicine, Wrocław, Poland
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Ralitsa Robeva
Ralitsa Robeva
Ushate ‘acad. IV. Penchev’, Department of Endocrinology, Faculty of Medicine, Medical University-Sofia, Sofia, Bulgaria
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Andromahi Vryonidou
Andromahi Vryonidou
Department of Endocrinology and Diabetes, Hellenic Red Cross Hospital, Athens, Greece
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Jelica Bjekic Macut
Jelica Bjekic Macut
Department of Endocrinology, UMC Bežanijska Kosa, Faculty of Medicine, University of Belgrade, Belgrade, Serbia
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Ioannis Androulakis
Ioannis Androulakis
Endocrine Unit, Athens Medical Centre, Athens, Greece
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Milica Opalic
Milica Opalic
Clinic of Endocrinology, Diabetes and Metabolic Diseases, Faculty of Medicine, University of Belgrade, Belgrade, Serbia
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Zadalla Mouslech
Zadalla Mouslech
1st Medical Propedeutic, Department of Internal Medicine, AHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece
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Andrej Milewicz
Andrej Milewicz
Department of Endocrinology, Diabetology and Isotope Therapy, University of Medicine, Wrocław, Poland
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Alessandra Gambineri
Alessandra Gambineri
Department of Medical and Surgical Science-DIMEC Endocrinology Unit, University of Bologna – S. Orsola-Mapighi Hospital, Italy
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Dimitrios Panidis
Dimitrios Panidis
Gynaecological Endocrinology Infirmary of the Second Department of Obstetrics and Gynaecology, Aristotle University of Thessaloniki, Thessaloniki, Greece
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Djuro Macut
Djuro Macut
Clinic of Endocrinology, Diabetes and Metabolic Diseases, Faculty of Medicine, University of Belgrade, Belgrade, Serbia
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, accompanied by oligomenorrhea, dominate the clinical picture followed by metabolic disorders including dysglycemia and dyslipidemia later in life ( 1 ). Moreover, progression of normoglycemia to either intermediate hyperglycemia or diabetes mellitus (T2DM) has
Zhenyu Liu
Zhenyu Liu
Department of Clinical Medicine, Beijing Luhe Hospital, Capital Medical University, Tongzhou District, Beijing, China
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Huixi Kong
Huixi Kong
Department of Clinical Medicine, Beijing Shijitan Hospital, Capital Medical University, Haidian District, Beijing, China
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Baoyu Zhang
Baoyu Zhang
Center for Endocrine Metabolism and Immune Diseases, Beijing Luhe Hospital, Capital Medical University, Tongzhou District, Beijing, China
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Introduction According to recent statistics, 529 million people will have diabetes worldwide in 2021, and the global age-standardized total diabetes prevalence will be 6.1% ( 1 ). Type 2 diabetes mellitus (T2DM) is the most frequent form of
Zhiyan Yu
Zhiyan Yu
Department of Endocrinology, Shanghai Fifth People’s Hospital, Fudan University, Shanghai, China
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Yueyue Wu
Yueyue Wu
Department of Endocrinology, Shanghai Fifth People’s Hospital, Fudan University, Shanghai, China
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Rui Zhang
Rui Zhang
Department of Endocrinology, Shanghai Fifth People’s Hospital, Fudan University, Shanghai, China
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Yue Li
Yue Li
Department of Endocrinology, Shanghai Fifth People’s Hospital, Fudan University, Shanghai, China
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Shufei Zang
Shufei Zang
Department of Endocrinology, Shanghai Fifth People’s Hospital, Fudan University, Shanghai, China
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Jun Liu
Jun Liu
Department of Endocrinology, Shanghai Fifth People’s Hospital, Fudan University, Shanghai, China
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subjects with T2DM were included in this study of whom 654 were male (266 non-NAFLD, 388 NAFLD) and 589 were female (217 non-NAFLD and 372 NAFLD). The clinical and laboratory characteristics are shown in Table 1 . Compared with non-NAFLD patients, those
Giovanni Fanni
Giovanni Fanni
Department of Medical Sciences, Clinical Diabetes and Metabolism, Uppsala University, Uppsala, Sweden
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Petros Katsogiannos
Petros Katsogiannos
Department of Medical Sciences, Clinical Diabetes and Metabolism, Uppsala University, Uppsala, Sweden
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Bipasha Nandi Jui
Bipasha Nandi Jui
Department of Medical Sciences, Clinical Diabetes and Metabolism, Uppsala University, Uppsala, Sweden
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Magnus Sundbom
Magnus Sundbom
Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
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Susanne Hetty
Susanne Hetty
Department of Medical Sciences, Clinical Diabetes and Metabolism, Uppsala University, Uppsala, Sweden
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Maria J Pereira
Maria J Pereira
Department of Medical Sciences, Clinical Diabetes and Metabolism, Uppsala University, Uppsala, Sweden
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Jan W Eriksson
Jan W Eriksson
Department of Medical Sciences, Clinical Diabetes and Metabolism, Uppsala University, Uppsala, Sweden
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Introduction Besides inducing significant and durable weight loss, Roux-en-Y gastric bypass (RYGB) improves glycemic control in insulin-resistant patients and can prevent or reverse type 2 diabetes mellitus (T2DM) ( 1 , 2 , 3 ). This
Chan Yang
Chan Yang
School of Nursing, Ningxia Medical University, Yinchuan, Ningxia, China
School of Public Health, Ningxia Medical University, Yinchuan, Ningxia, China
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School of Public Health, Ningxia Medical University, Yinchuan, Ningxia, China
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Yadi Zhang
Yadi Zhang
School of Public Health, Ningxia Medical University, Yinchuan, Ningxia, China
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Juan Li
Juan Li
School of Public Health, Ningxia Medical University, Yinchuan, Ningxia, China
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Xiaowei Liu
Xiaowei Liu
School of Public Health, Ningxia Medical University, Yinchuan, Ningxia, China
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Jiangwei Qiu
Jiangwei Qiu
School of Public Health, Ningxia Medical University, Yinchuan, Ningxia, China
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Jiaxing Zhang
Jiaxing Zhang
School of Public Health, Ningxia Medical University, Yinchuan, Ningxia, China
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Xiuying Liu
Xiuying Liu
School of Public Health, Ningxia Medical University, Yinchuan, Ningxia, China
Key Laboratory of Environmental Factors and Chronic Disease Control, Ningxia Medical University, Yinchuan, Ningxia, China
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Key Laboratory of Environmental Factors and Chronic Disease Control, Ningxia Medical University, Yinchuan, Ningxia, China
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Yuhong Zhang
Yuhong Zhang
School of Public Health, Ningxia Medical University, Yinchuan, Ningxia, China
Key Laboratory of Environmental Factors and Chronic Disease Control, Ningxia Medical University, Yinchuan, Ningxia, China
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Key Laboratory of Environmental Factors and Chronic Disease Control, Ningxia Medical University, Yinchuan, Ningxia, China
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Yi Zhao
Yi Zhao
School of Public Health, Ningxia Medical University, Yinchuan, Ningxia, China
Key Laboratory of Environmental Factors and Chronic Disease Control, Ningxia Medical University, Yinchuan, Ningxia, China
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Key Laboratory of Environmental Factors and Chronic Disease Control, Ningxia Medical University, Yinchuan, Ningxia, China
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weight loss due to unknown causes), or a past medical history of T2DM. Prediabetes was defined as a fasting plasma glucose ≥6.1 mmol/L and <7.0 mmol/L. Normoglycemia was defined as a fasting plasma glucose level <6.1 mmol/L. Body mass index (BMI) was
Xi Cao
Xi Cao
Beijing Diabetes Institute, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Ming Lu
Ming Lu
Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Rong-Rong Xie
Rong-Rong Xie
Beijing Diabetes Institute, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Li-Ni Song
Li-Ni Song
Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Wei-Li Yang
Wei-Li Yang
Beijing Diabetes Institute, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Zhong Xin
Zhong Xin
Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Guang-Ran Yang
Guang-Ran Yang
Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Jin-Kui Yang
Jin-Kui Yang
Beijing Diabetes Institute, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Introduction The prevalence of type 2 diabetes mellitus (T2DM) is increasing globally, and diabetic complications affect millions of people worldwide ( 1 , 2 ). Diabetic eye diseases, such as diabetic retinopathy (DR) and diabetic macular
Shaomin Shi
Shaomin Shi
Division of Nephrology, The First Affiliated Hospital of Yangtze University, Jingzhou, China
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Xinghua Chen
Xinghua Chen
Division of Nephrology, Renmin Hospital of Wuhan University, Wuhan, China
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Wen Yu
Wen Yu
Department of Immunology, School of Medicine, Yangtze University, Jingzhou, China
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Xiaolan Ke
Xiaolan Ke
Division of Nephrology, The First Affiliated Hospital of Yangtze University, Jingzhou, China
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Tean Ma
Tean Ma
Division of Nephrology, The First Affiliated Hospital of Yangtze University, Jingzhou, China
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decreasing trend in renal GLP-1R protein expression compared with the NC group, which verified that there was a reduction in renal GLP-1R protein expression in the T2DM mouse model. The hypoglycemic effect of Degu insulin does not reverse this change. In this
