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Department of Pediatrics, Navarra Hospital Complex, Pamplona, Spain
Navarra Institute for Health Research (IdisNA), Pamplona, Spain
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Navarra Institute for Health Research (IdisNA), Pamplona, Spain
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Navarra Institute for Health Research (IdisNA), Pamplona, Spain
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, IL, USA). Statistical significance was accepted when P -value was <0.05. Parents and/or legal guardians were appropriately informed and gave consent for the participation of the participants in this study in all cases. This study was approved by
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Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK
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( 31 , 32 , 33 , 34 , 35 , 36 , 37 ). Therefore, we classified participants as pre-pubertal (Tanner stage 1, hereafter referred to as stage A), early pubertal (Tanner stages 2 and 3, hereafter referred to as stage B), or late-pubertal (Tanner