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kynurenine metabolism arm, only 3-hydroxyanthranilate 3,4-dioxygenase (HAAO) could be detected. All the differentially expressed proteins showed significantly lower abundance in fibrotic mesenteric stroma compared to non-fibrotic mesenteric stroma
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mostly exists in the form of a JunD-menin complex ( 34 , 35 ). Two isoforms of JunD are currently known: the full-length JunD-FL and the truncated ΔJunD. Transcription of these isoforms begins at two different start codons of the same mRNA. Menin
European Institute for Molecular Imaging (EIMI), University of Münster, Münster, Germany
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the efficacy of BRAF-inhibition, including activation of ERBB3 , EGFR , PI3K , IL6 , HGF/MET and the reactivation of the MAPK pathway through an acquired KRAS G12D mutation. Inhibition of ERK, a strategy for overcoming BRAF and MEKinhibition