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included TSS, bromocriptine, or cabergoline for GHPA, and ATD or 131I for GD. Table 2 Cases of GHPA combined with GD in the published literature. Author Year Country Age (years)/ gender Clinical manifestations GH (ng/mL) IGF-1
Department of Diabetes & Endocrinology, Skåne University Hospital, Malmö, Sweden
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Department of Diabetes & Endocrinology, Skåne University Hospital, Malmö, Sweden
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Department of Ophthalmology, Skåne University Hospital, Malmö, Sweden
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Department of Diabetes & Endocrinology, Skåne University Hospital, Malmö, Sweden
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TSHR induces cross-talk with insulin-like growth factor 1 receptor (IGF1R) ( 10 ), which results in elevated levels of hyaluronic acid, leading to the disruption of the extraocular muscles ( 11 ). T cells bind to CD40 on orbital fibroblasts and induce
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Clinical Research Centre, Medical University of Bialystok, Bialystok, Poland
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CXCL10 and that decrease was linked with a reduction of TRAb titers ( 13 , 15 ). Current management For a very long time, the mainstay of GO treatment has been the administration of i.v. glucocorticosteroids (ivGCS), which was frequently
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Department of Endocrinology and Metabolism, Drum Tower Clinical Medical College, Southeast University, Nanjing, China
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thyrotropin receptor, other autoantigens and antibodies are involved in the development of TED, among which, the insulin-like growth factor I receptor (IGF-I) receptor plays a central role ( 21 , 22 ). Future studies are needed to test the possible
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prostate gland, suggesting direct actions of THs on this target organ. This paper reviews: (i) elements related to TH transport, bioavailability, and thyroid signaling that have been identified in the prostate; (ii) the influence of the thyroid status on
The First Affiliated Hospital, Department of Otorhinolaryngology, Hengyang Medical School, University of South China, Hengyang, Hunan, China
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The First Affiliated Hospital, Department of Endocrinology and Metabolism, Hengyang Medical School, University of South China, Hengyang, Hunan, China
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that in tissues without cervical lymph node metastasis (LM(−)) ( n = 11 patients for LM(−) and 27 patients for LM(+), FC = 2.538, P = 0.0349) ( Fig. 4I ). Immunohistochemistry further revealed that HMGA1 was mainly expressed in the nucleus of TC