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Annalisa Blasetti
Annalisa Blasetti
Department of Paediatrics, University of Chieti, Chieti, Italy
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Valeria Castorani
Valeria Castorani
Department of Paediatrics, University of Chieti, Chieti, Italy
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Nella Polidori
Nella Polidori
Department of Paediatrics, University of Chieti, Chieti, Italy
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Ilaria Mascioli
Ilaria Mascioli
Department of Paediatrics, University of Chieti, Chieti, Italy
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Francesco Chiarelli
Francesco Chiarelli
Department of Paediatrics, University of Chieti, Chieti, Italy
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Cosimo Giannini
Cosimo Giannini
Department of Paediatrics, University of Chieti, Chieti, Italy
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, particularly intensified insulin regimens and novel technologies, can improve metabolic control in patients with T1D, therefore preventing abnormalities of the GH–IGF-I axis, thus potentially leading to normal growth and final height similar to unaffected peers
Xiaohui Qi
Xiaohui Qi
Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Ping He
Ping He
Shanghai Hospital Link Center, Shanghai Hospital Development Center, Shanghai, China
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Huayan Yao
Huayan Yao
Computer Net Center, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Huanhuan Sun
Huanhuan Sun
Wonders Information Co. Ltd, Shanghai, China
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Jiying Qi
Jiying Qi
Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Min Cao
Min Cao
Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Bin Cui
Bin Cui
Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Guang Ning
Guang Ning
Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Pezzino V Squatrito S Belfiore A Vigneri R . The role of insulin receptors and IGF-I receptors in cancer and other diseases . Archives of Physiology and Biochemistry 2008 114 23 – 37 . ( https://doi.org/10.1080/13813450801969715 ) 10 Calle EE
Peter Wolf
Peter Wolf
Université Paris-Saclay, Inserm, Physiologie et Physiopathologie Endocriniennes, Assistance Publique-Hôpitaux de Paris, Hôpital Bicêtre, Service d’Endocrinologie et des Maladies de la Reproduction, Centre de Référence des Maladies Rares de l’Hypophyse, Le Kremlin-Bicêtre, France
Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
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Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
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Alexandre Dormoy
Alexandre Dormoy
Université Paris-Saclay, Inserm, Physiologie et Physiopathologie Endocriniennes, Assistance Publique-Hôpitaux de Paris, Hôpital Bicêtre, Service d’Endocrinologie et des Maladies de la Reproduction, Centre de Référence des Maladies Rares de l’Hypophyse, Le Kremlin-Bicêtre, France
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Luigi Maione
Luigi Maione
Université Paris-Saclay, Inserm, Physiologie et Physiopathologie Endocriniennes, Assistance Publique-Hôpitaux de Paris, Hôpital Bicêtre, Service d’Endocrinologie et des Maladies de la Reproduction, Centre de Référence des Maladies Rares de l’Hypophyse, Le Kremlin-Bicêtre, France
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Sylvie Salenave
Sylvie Salenave
Université Paris-Saclay, Inserm, Physiologie et Physiopathologie Endocriniennes, Assistance Publique-Hôpitaux de Paris, Hôpital Bicêtre, Service d’Endocrinologie et des Maladies de la Reproduction, Centre de Référence des Maladies Rares de l’Hypophyse, Le Kremlin-Bicêtre, France
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Jacques Young
Jacques Young
Université Paris-Saclay, Inserm, Physiologie et Physiopathologie Endocriniennes, Assistance Publique-Hôpitaux de Paris, Hôpital Bicêtre, Service d’Endocrinologie et des Maladies de la Reproduction, Centre de Référence des Maladies Rares de l’Hypophyse, Le Kremlin-Bicêtre, France
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Peter Kamenický
Peter Kamenický
Université Paris-Saclay, Inserm, Physiologie et Physiopathologie Endocriniennes, Assistance Publique-Hôpitaux de Paris, Hôpital Bicêtre, Service d’Endocrinologie et des Maladies de la Reproduction, Centre de Référence des Maladies Rares de l’Hypophyse, Le Kremlin-Bicêtre, France
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Philippe Chanson
Philippe Chanson
Université Paris-Saclay, Inserm, Physiologie et Physiopathologie Endocriniennes, Assistance Publique-Hôpitaux de Paris, Hôpital Bicêtre, Service d’Endocrinologie et des Maladies de la Reproduction, Centre de Référence des Maladies Rares de l’Hypophyse, Le Kremlin-Bicêtre, France
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). Among the 25 patients resistant to first-generation SRLs, 16 (64%) normalized their IGF-I levels under pasireotide. Figure 1 (A) Longitudinal changes in IGF-1 (given as % of ULN) in all patients; patients who had normalized IGF-1 levels according
Wenjun Long
Wenjun Long
Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
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Tuo Zhou
Tuo Zhou
Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
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Xiuping Xuan
Xiuping Xuan
Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China
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Qiuli Cao
Qiuli Cao
Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China
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Zuojie Luo
Zuojie Luo
Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China
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Yingfen Qin
Yingfen Qin
Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China
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Qin Ning
Qin Ning
Department of Infectious Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
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Xiaoping Luo
Xiaoping Luo
Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
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Xuemei Xie
Xuemei Xie
Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China
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genetic as well as biochemical approaches have independently confirmed that mTOR/S6K plays a novel and essential role in the regulation of cell autonomous insulin/IGF-I sensitivity through affecting IRS-1 function ( 35 ), we also analyzed the expression of
Shaomin Shi
Shaomin Shi
Division of Nephrology, The First Affiliated Hospital of Yangtze University, Jingzhou, China
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Xinghua Chen
Xinghua Chen
Division of Nephrology, Renmin Hospital of Wuhan University, Wuhan, China
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Wen Yu
Wen Yu
Department of Immunology, School of Medicine, Yangtze University, Jingzhou, China
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Xiaolan Ke
Xiaolan Ke
Division of Nephrology, The First Affiliated Hospital of Yangtze University, Jingzhou, China
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Tean Ma
Tean Ma
Division of Nephrology, The First Affiliated Hospital of Yangtze University, Jingzhou, China
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mature IL-1β and IL-1 ( 41 , 42 , 43 ), and activates pro-caspase-1, which cleaves to activated caspase-1 ( 44 ) and cleaves GSDMD to GSDMD-C and GSDMD-N (i.e. cleaved-GSDMD in this paper) ( 45 , 46 ), further causing cellular scorching ( 47 ) and
Giovanni Fanni
Giovanni Fanni
Department of Medical Sciences, Clinical Diabetes and Metabolism, Uppsala University, Uppsala, Sweden
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Petros Katsogiannos
Petros Katsogiannos
Department of Medical Sciences, Clinical Diabetes and Metabolism, Uppsala University, Uppsala, Sweden
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Bipasha Nandi Jui
Bipasha Nandi Jui
Department of Medical Sciences, Clinical Diabetes and Metabolism, Uppsala University, Uppsala, Sweden
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Magnus Sundbom
Magnus Sundbom
Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
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Susanne Hetty
Susanne Hetty
Department of Medical Sciences, Clinical Diabetes and Metabolism, Uppsala University, Uppsala, Sweden
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Maria J Pereira
Maria J Pereira
Department of Medical Sciences, Clinical Diabetes and Metabolism, Uppsala University, Uppsala, Sweden
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Jan W Eriksson
Jan W Eriksson
Department of Medical Sciences, Clinical Diabetes and Metabolism, Uppsala University, Uppsala, Sweden
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GH/IGF-I axis in severe obesity – and a comparison with GH deficiency . European Journal of Endocrinology 2006 154 53 – 59 . ( https://doi.org/10.1530/eje.1.02069 ) 28 Devesa J The complex world of regulation of pituitary growth hormone secretion
Zhou Zheng
Zhou Zheng
Department of Medical Laboratory, The Affiliated Luohu Hospital of Shenzhen University, Shenzhen University, Shenzhen, Guangdong, China
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Xiuming Zhang
Xiuming Zhang
Department of Medical Laboratory, The Affiliated Luohu Hospital of Shenzhen University, Shenzhen University, Shenzhen, Guangdong, China
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Fanggui Wu
Fanggui Wu
Department of Reproductive Medicine, The Affiliated Luohu Hospital of Shenzhen University, Shenzhen University, Shenzhen, Guangdong, China
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Haizhen Liao
Haizhen Liao
Department of Reproductive Medicine, The Affiliated Luohu Hospital of Shenzhen University, Shenzhen University, Shenzhen, Guangdong, China
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Huan Zhao
Huan Zhao
Department of Reproductive Medicine, The Affiliated Luohu Hospital of Shenzhen University, Shenzhen University, Shenzhen, Guangdong, China
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Minqi Zhang
Minqi Zhang
Department of Reproductive Medicine, The Affiliated Luohu Hospital of Shenzhen University, Shenzhen University, Shenzhen, Guangdong, China
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Shangjie Liu
Shangjie Liu
Department of Reproductive Medicine, The Affiliated Luohu Hospital of Shenzhen University, Shenzhen University, Shenzhen, Guangdong, China
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BMI and are facing fertility challenges. Materials and methods Participants This retrospective study collected data from female patients who underwent assisted reproduction (i.e. IVF/ICSI treatment using fresh/frozen embryo transfer
Laura Hasse
Laura Hasse
Department of Pediatric Dermatology and Allergology, Children’s Hospital Auf der Bult, Hannover, Germany
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Dagmar Jamiolkowski
Dagmar Jamiolkowski
Department of Pediatric Dermatology and Allergology, Children’s Hospital Auf der Bult, Hannover, Germany
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Felix Reschke
Felix Reschke
Department of Pediatric Diabetology, Children’s Hospital Auf der Bult, Hannover, Germany
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Kerstin Kapitzke
Kerstin Kapitzke
Department of Pediatric Diabetology, Children’s Hospital Auf der Bult, Hannover, Germany
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Jantje Weiskorn
Jantje Weiskorn
Department of Pediatric Diabetology, Children’s Hospital Auf der Bult, Hannover, Germany
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Olga Kordonouri
Olga Kordonouri
Department of Pediatric Diabetology, Children’s Hospital Auf der Bult, Hannover, Germany
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Torben Biester
Torben Biester
Department of Pediatric Diabetology, Children’s Hospital Auf der Bult, Hannover, Germany
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Hagen Ott
Hagen Ott
Department of Pediatric Dermatology and Allergology, Children’s Hospital Auf der Bult, Hannover, Germany
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distensae were observed in 65 subjects (63%) and occurred primarily in the abdominal region, followed by the brachial and dorsal regions. A significant correlation was found between striae and the results of the BIA ( r = 0.354, P < 0.001), i.e. increased
Jonathan Hazlehurst
Jonathan Hazlehurst
Department of Diabetes and Endocrinology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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Bernard Khoo
Bernard Khoo
Endocrinology, Division of Medicine, University College London, London, UK
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Carolina Brito Lobato
Carolina Brito Lobato
Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Department of Medicine, Copenhagen University Hospital – Amager and Hvidovre, Hvidovre, Denmark
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Department of Medicine, Copenhagen University Hospital – Amager and Hvidovre, Hvidovre, Denmark
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Ibiyemi Ilesanmi
Ibiyemi Ilesanmi
Section of Endocrinology and Investigative Medicine, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK
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Sally Abbott
Sally Abbott
Department of Dietetics, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK
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Tin Chan
Tin Chan
Faculty of Medicine, Chinese University of Hong Kong, Hong Kong
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Sanesh Pillai
Sanesh Pillai
Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK
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Kate Maslin
Kate Maslin
School of Nursing and Midwifery, University of Plymouth, Plymouth, UK
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Sanjay Purkayastha
Sanjay Purkayastha
Brunel University, London, UK
Imperial College Healthcare NHS Trust, St Mary’s Hospital, London, UK
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Imperial College Healthcare NHS Trust, St Mary’s Hospital, London, UK
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Barbara McGowan
Barbara McGowan
Endocrinology, Guys’ and St Thomas’s NHS Foundation Trust, London, UK
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Rob Andrews
Rob Andrews
University of Exeter Medical School, Exeter, UK
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Eveleigh Nicholson
Eveleigh Nicholson
Portsmouth Hospitals University NHS Trust, Portsmouth, UK
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Katherine McCullough
Katherine McCullough
Royal Surrey County Hospital, Guildford, UK
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Lorraine Albon
Lorraine Albon
University Hospitals Sussex NHS Foundation Trust, Worthing, UK
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Rachel Batterham
Rachel Batterham
Endocrinology, Division of Medicine, University College London, London, UK
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Georgios K Dimitriadis
Georgios K Dimitriadis
King's College Hospital NHS Foundation Trust, London, UK
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Shareen Forbes
Shareen Forbes
BHF Centre for Cardiovascular Science, Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, UK
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Gavin Bewick
Gavin Bewick
School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK
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Tricia M-M Tan
Tricia M-M Tan
Section of Endocrinology and Investigative Medicine, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK
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, occurring typically 2–4 h after ingestion of food, and presenting with documented low glucose values and hypoglycaemic symptomatology, which subsides once euglycaemia is restored – i.e. Whipple’s triad. PBH is associated with a lower quality of life, which
Clemens Kamrath
Clemens Kamrath
Center of Child and Adolescent Medicine, Justus Liebig University, Giessen, Germany
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Alexander Eckert
Alexander Eckert
German Center for Diabetes Research (DZD), Munich-Neuherberg, Germany
Institute of Epidemiology and Medical Biometry, ZIBMT, Ulm University, Ulm, Germany
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Institute of Epidemiology and Medical Biometry, ZIBMT, Ulm University, Ulm, Germany
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Birgit Rami-Merhar
Birgit Rami-Merhar
Department of Pediatrics and Adolescent Medicine, Medical University Vienna, Vienna, Austria
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Sebastian Kummer
Sebastian Kummer
Department of General Pediatrics, Neonatology and Pediatric Cardiology, Heinrich Heine University, Medical Faculty, Duesseldorf, Germany
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Martin Wabitsch
Martin Wabitsch
Center for Rare Endocrine Diseases, Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics and Adolescent Medicine, Ulm University Medical Centre, Ulm, Germany
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Katharina Laubner
Katharina Laubner
Division of Endocrinology and Diabetology, Department of Medicine II, Medical Center – University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany
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Florian Kopp
Florian Kopp
Forth Clinical Department of Medicine, Academic Teaching Hospital Augsburg, Augsburg, Germany
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Silvia Müther
Silvia Müther
Center for Pediatric Diabetology, DRK-Kliniken-Berlin Westend, Berlin, Germany
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Steffen Mühldorfer
Steffen Mühldorfer
Department for Gastroenterology, Endocrinology and Metabolic Diseases, Bayreuth University Hospital, Friedrich-Alexander University Erlangen-Nuremberg, Bayreuth, Germany
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Reinhard W Holl
Reinhard W Holl
German Center for Diabetes Research (DZD), Munich-Neuherberg, Germany
Institute of Epidemiology and Medical Biometry, ZIBMT, Ulm University, Ulm, Germany
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Institute of Epidemiology and Medical Biometry, ZIBMT, Ulm University, Ulm, Germany
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. Treatment with recombinant human insulin-like growth factor (rhIGF)-I/rhIGF binding protein-3 complex improves metabolic control in subjects with severe insulin resistance . Journal of Clinical Endocrinology and Metabolism 2010 95 2113 – 2122 . ( https
