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The role of menin in bone pathology

Anna Gorbacheva

Anna Gorbacheva Endocrinology Research Center, Moscow, Russian Federation

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Anna Eremkina

Anna Eremkina Endocrinology Research Center, Moscow, Russian Federation

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Daria Goliusova

Daria Goliusova Endocrinology Research Center, Moscow, Russian Federation

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Julia Krupinova

Julia Krupinova Endocrinology Research Center, Moscow, Russian Federation

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, and

Natalia Mokrysheva

Natalia Mokrysheva Endocrinology Research Center, Moscow, Russian Federation

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been suggested that menin may specifically bind to some DNA regions via two leucine zipper motifs ( 12 ). The N-terminus of menin contains five motifs usually found in GTPases and GTP-binding proteins. At the same time, the affinity of menin for GTP