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.55–1.8 nmol/L, whereas s-androstenedione was 3.5 (IQR 1.0–6.6) and 3.2 (IQR 1.2–6.8), normal range of 2.4–8.9 nmol/L. Mean ICC varied from 0.82 to 0.99. Serum DHEAs had the highest ICC (0.99 (95% CI 0.98–0.99)) corresponding to excellent repeatability between
International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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Pediatric Endocrinology Clinic, Department of Pediatrics, Aretaeio Hospital, Nicosia, Cyprus
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Department of Clinical Medicine, University of Copenhagen, Denmark
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, 17-OHP, androstenedione, and DHEAS ( 15 , 16 ), and inhibin B and AMH ( 17 ). Due to missing reference data in specific age ranges, standardization of hormone concentrations was not possible in all patients < 18 years ( Table 1 ). Biochemical s
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Obesity, Type 2 Diabetes and Immunometabolism Research Group, School of Cardiovascular and Metabolic Medicine & Sciences, Faculty of Life Course Sciences, King’s College London, London, UK
Division of Reproductive Health, Warwick Medical School, University of Warwick, Coventry, UK
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), adrenocorticotrophic hormone (ACTH), cortisol-binding globulin (CBG), thyroxine-binding globulin (TBG), gonadotrophins, DHEAS, testosterone and plasma EDTA ACTH were collected using BD Vacutainer during the same venepuncture. Samples were stored at −80°C until analysis
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NIHR Health Protection Research Unit on Chemical Radiation Threats and Hazards, Imperial College London, London, UK
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testosterone, A4, 11KT, 17-OHP, 11OHA4 and DHEA. Saliva samples for females were analysed for OE2 and DHEA only. Sample assay methods were the same for samples collected from both SCAMP participants and healthy adult volunteers, as follows. Testosterone, A4, 17
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patients underwent at least one DST. At the discretion of the patient’s physician, the study was completed by measuring urinary cortisol levels, adrenocorticotropic hormone (ACTH), dehydroepiandrosterone sulfate (DHEA-S) and night-time salivary cortisol. In
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Introduction Primary adrenal insufficiency (PAI) is characterised by inadequate steroid hormone secretion caused by intrinsic adrenal cortex disease ( 1 ). The most common causes of PAI are Addison’s disease (AD), usually resulting from
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and Human Reproduction 2017 46 1 – 7 . ( https://doi.org/10.1016/j.jgyn.2016.01.002 ) 49 Schwarze JE Canales J Crosby J Ortega-Hrepich C Villa S & Pommer R . DHEA use to improve likelihood of IVF/ICSI success in patients with
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management of subclinical hypercortisolism . Endocrine 2017 56 308 – 316 . ( https://doi.org/10.1007/s12020-017-1268-7 ) 47 Liu MS Lou Y Chen H Wang YJ Zhang ZW Li P & Zhu DL . Performance of DHEAS as a screening test for autonomous
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. Assessment of DHEAS, cortisol, and DHEAS/cortisol ratio in patients with COVID-19: a pilot study. Hormones 2022 21 515 – 518 . ( https://doi.org/10.1007/s42000-022-00382-x ) 3 Yavropoulou MP Filippa MG Mantzou A Ntziora F Mylona M Tektonidou MG
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countries ( 1 ) and the lowest in Japan. Despite the advent of glucocorticoid replacement therapy in the early 1950s, life expectancy remains lower than in the general population ( 2 ), with increased morbidity and impaired quality of life ( 3 , 4